Levels of arsenic in the United States food supply

Regulating oral rinses has been and still is a topic of debate and confusion. Oral rinses are products that are mainly used for cleaning, perfuming and changing the appearance of the teeth, which in turn improves the individual’s external appearance. Adding medicinal ingredients to these rinses, it can then be used for the elimination and/or prevention of some oral diseases, an example being gingivitis. The United States Food and Drug Administration placed guidelines which state that mouthwashes with possible therapeutic properties should be registered as drugs rather than cosmetics. Meanwhile, on a different continent, Germany along with the other members of the European Union decided not to categorize mouthwashes as drugs, but rather as cosmetics, using its sole purpose of cleaning and beautifying the teeth as the excuse. The following research will thoroughly differentiate between the diverse regulatory systems forced upon mouthwashes across the two countries—the United States and Germany.

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Analysis of Crowdsourced Metformin Tablets from Individuals Reveals Widespread Contamination with N-Nitrosodimethylamine (NDMA) in the United States

10.1101/2020.05.22.20110635 ◽

2020 ◽

Cited By ~ 1

Author(s):

Qian Wu ◽

Evgenia Kvitko ◽

Amber Jessop ◽

Shannon Williams ◽

Ryan C. Costantino ◽

...

Keyword(s):

United States ◽

High Resolution Mass Spectrometry ◽

Daily Intake ◽

The United States ◽

Product Recalls ◽

Acceptable Daily Intake ◽

Drug Products ◽

Post Market ◽

United States Food ◽

States Food

AbstractRecent reports of metformin drug products contaminated with unacceptable levels of the probable human carcinogen N-Nitrosodimethylamine (NDMA) prompted a national sampling of post-market metformin drug products. To most broadly sample the market and minimize supply chain bias, metformin medication samples were crowdsourced directly from individuals across many states in the United States. 128 samples were received, and liquid chromatography-high resolution mass spectrometry tests for a panel of nitrosamines revealed significant levels of NDMA that trend with labeling company. 42% of all medication samples contained detectable levels of NDMA and, when scaled to maximum daily tablet dose, 36% of all medication samples contained NDMA levels exceeding the FDA daily acceptable intake limit. The highest NDMA detection from the tested samples was 1565 ng per tablet, which, when commonly taken four times a day, is 65 times the United States Food and Drug Administration (FDA) acceptable daily intake limit. Results underscore the need for immediate product recalls of tainted medications and an overall investigation of metformin manufacturing practices.

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Program planning with Tobit analysis—the United States food stamp case

Socio-Economic Planning Sciences ◽

10.1016/0038-0121(80)90039-7 ◽

1980 ◽

Vol 14 (2) ◽

pp. 91-95

Author(s):

J.E. Epperson ◽

M.R. Holmes ◽

C.L. Huang ◽

W.K. Scearce

Keyword(s):

United States ◽

Program Planning ◽

The United States ◽

Food Stamp ◽

Tobit Analysis ◽

United States Food ◽

States Food

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