scholarly journals Bone as a Possible Target of Chemical Toxicity of Natural Uranium in Drinking Water

2005 ◽  
Vol 113 (1) ◽  
pp. 68-72 ◽  
Author(s):  
Päivi Kurttio ◽  
Hannu Komulainen ◽  
Aila Leino ◽  
Laina Salonen ◽  
Anssi Auvinen ◽  
...  
Keyword(s):  
Drinking Water ◽  
Natural Uranium ◽  
Chemical Toxicity

Exposure assessment of natural uranium from drinking water

2016 ◽  
Vol 18 (12) ◽  
pp. 1540-1549 ◽  
Author(s):  
Rajan Jakhu ◽  
Rohit Mehra ◽  
H. M. Mittal
Keyword(s):  
Drinking Water ◽  
Exposure Assessment ◽  
Uranium Concentration ◽  
Natural Uranium

The uranium concentration in the drinking water of the residents of the Jaipur and Ajmer districts of Rajasthan has been measured for exposure assessment.

INTERNAL DOSE ASSESSMENT OF NATURAL URANIUM FROM DRINKING WATER BASED ON BIOKINETIC MODELING AND INDIVIDUAL BIOASSAY MONITORING: A STUDY OF A FINNISH FAMILY

2006 ◽  
Vol 90 (6) ◽  
pp. 533-543 ◽  
Author(s):  
Wei Bo Li ◽  
Laina Salonen ◽  
Maarit Muikku ◽  
Wolfgang Wahl ◽  
Vera H??llriegl ◽  
...  
Keyword(s):  
Drinking Water ◽  
Natural Uranium ◽  
Dose Assessment ◽  
Internal Dose ◽  
Water Based ◽  
Biokinetic Modeling

scholarly journals Assessment of the Central Effects of Natural UraniumviaBehavioural Performances and the Cerebrospinal Fluid Metabolome

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
P. Lestaevel ◽  
S. Grison ◽  
G. Favé ◽  
C. Elie ◽  
B. Dhieux ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Drinking Water ◽  
Locomotor Activity ◽  
Brain Function ◽  
Spatial Working Memory ◽  
Natural Uranium ◽  
Female Rats ◽  
Male Rats ◽  
The Central Nervous System ◽  
And Control

Natural uranium (NU), a component of the earth’s crust, is not only a heavy metal but also an alpha particle emitter, with chemical and radiological toxicity. Populations may therefore be chronically exposed to NU through drinking water and food. Since the central nervous system is known to be sensitive to pollutants during its development, we assessed the effects on the behaviour and the cerebrospinal fluid (CSF) metabolome of rats exposed for 9 months from birth to NUvialactation and drinking water (1.5, 10, or 40 mg·L−1for male rats and 40 mg·L−1for female rats). Medium-term memory decreased in comparison to controls in male rats exposed to 1.5, 10, or 40 mg·L−1NU. In male rats, spatial working memory and anxiety- and depressive-like behaviour were only altered by exposure to 40 mg·L−1NU and any significant effect was observed on locomotor activity. In female rats exposed to NU, only locomotor activity was significantly increased in comparison with controls. LC-MS metabolomics of CSF discriminated the fingerprints of the male and/or female NU-exposed and control groups. This study suggests that exposure to environmental doses of NU from development to adulthood can have an impact on rat brain function.

Investigation of 238U, 234U And 210Po Content in Selected Bulgarian Drinking Water

2021 ◽  
Vol 30 (2) ◽  
pp. 119-133
Author(s):  
Bozhidar Slavchev ◽  
◽  
Elena Geleva ◽  
Blagorodka Veleva ◽  
Hristo Protohristov ◽  
...  
Keyword(s):  
Drinking Water ◽  
Dose Calculation ◽  
Natural Uranium ◽  
World Health ◽  
Reference Level ◽  
Human Consumption ◽  
Drinking Waters ◽  
Activity Measurements ◽  
Effective Doses ◽  
Health Organization

The radioactivity of selected sources of drinking water in Southern Bulgaria was investigated using 238U, 234U and 210Po activity measurements and dose calculation, respectively. The activities of 238U, 234U and 210Po varied from 226 to 826 mBq/L, 274 to 1623 mBq/L and < 0.6 to 25.5 mBq/L, respectively, being lower then derived concentrations for radioactivity in water intended for human consumption of the considered radionuclides, given in EC Directive 2013/51/EURATOM. In some drinking waters the mass concentration of natural uranium exceeded the set maximum chemical concentration level of 0.030 mg/L. A radioactive disequilibrium between 234U and 238U in water was detected. Based on the radionuclide activity concentrations total annual effective ingestion doses for adults, as well as contribution of each particular radionuclide to the total doses, were assessed and discussed. Тhe lowest contribution to the annual effective doses was found for 210Po and the highest for 234U. The results show that the annual effective doses of residents are below the reference level of 100 μSv/y according to the recommendations of the World Health Organization. The obtained new results are used to assess the radiation status of the investigated water.

scholarly journals Radiological and chemical toxicity due to ingestion of uranium through drinking water in the environment of Bangalore, India

2015 ◽  
Vol 35 (2) ◽  
pp. 447-455 ◽  
Author(s):  
Gladys Mathews ◽  
N Nagaiah ◽  
M B Karthik Kumar ◽  
M R Ambika
Keyword(s):  
Drinking Water ◽  
Chemical Toxicity

Chronic exposure to natural uranium via drinking water affects bone in growing rats

2012 ◽  
Vol 1820 (7) ◽  
pp. 1121-1127 ◽  
Author(s):  
Ndéye Marième Wade-Gueye ◽  
Olivia Delissen ◽  
Patrick Gourmelon ◽  
Jocelyne Aigueperse ◽  
Isabelle Dublineau ◽  
...  
Keyword(s):  
Drinking Water ◽  
Chronic Exposure ◽  
Natural Uranium ◽  
Growing Rats

scholarly journals Solid-liquid exchange between uranium and a synthetic apatite: towards uranium decorporation from bone matrix

2019 ◽  
Vol 14 ◽  
pp. 06004
Author(s):  
Jingxian Wang ◽  
Damien Bourgeois ◽  
Daniel Meyer
Keyword(s):  
Type I Collagen ◽  
Bone Matrix ◽  
Natural Uranium ◽  
Type I ◽  
Chemical Toxicity ◽  
Acute Effects ◽  
Liquid Equilibrium ◽  
Solid Liquid ◽  
Bone Apatite

Natural uranium exhibits chemical toxicity, especially known with its acute effects on kidney. Simultaneously, it has been proved that uranium accumulates in bones during long-term exposure[1] but its chronical effects on bones are not clear. Particularly the mechanisms associated to accumulation into and release from bones are unknown, which is key to design and test decorporation reagents in future. Bone is a complicated organ, composed of mineralized apatite and organic compounds (mostly type I collagen). Our work is dedicated to the understanding of how uranium is accumulated in the inorganic bone matrix through chemical pathways, and what factors influence the solid/liquid equilibrium between uranium and the bone. To fulfil this goal, apatite materials which mimic bone apatite have been synthesized, with and without uranium. Such apatite materials have been pre-equilibrated with a fluid mimicking blood plasma at physiological pH=7.4.

scholarly journals Issues of establishing the permissible discharge levels of 238U to surface waters taking into account its radiation and toxic effects

2020 ◽  
Vol 13 (2) ◽  
pp. 41-46
Author(s):  
A. I. Kryshev ◽  
T. G. Sazykina ◽  
N. N. Pavlova
Keyword(s):  
Drinking Water ◽  
Water Supply ◽  
Surface Waters ◽  
Maximum Permissible Concentration ◽  
Drinking Water Supply ◽  
Toxic Effects ◽  
Chemical Toxicity ◽  
Annual Dose ◽  
Water Object ◽  
Radioactive Substances

At present, discharges of 238U to surface waters by nuclear industry enterprises are limited by radiation factor. Registration and control of 238U discharges to water bodies is performed in units of radioactivity (Bq/year) according to the current permit for the water discharge of radioactive substances. At the same time, uranium belongs to the 1st hazard class by its chemical toxicity (extremely dangerous chemicals), it has hygienic standard for content in surface waters. A comparison was made for the limitation of 238U intake to surface waters, taking into account radiation exposure and chemical toxicity. Activity concentration of 238U in water was calculated, at which the annual dose for a critical population group from water use would be 0,1 mSv/year (scenario 1 – the water object is used for drinking water supply) or 1 mSv/year (scenario 2 – the water object is not used for drinking water supply). The calculated activity concentrations were expressed in units of mass concentrations and compared with the maximum permissible concentration of uranium in water, established in Russia, 15 mkg/L. It is shown that compliance with the radiation safety norms does not automatically guarantee compliance with the current hygienic standards for limiting the toxic effects of uranium on population and the environment. The concentration of 238U in water producing the annual dose to population 0,1 mSv taking into account all exposure pathways, exceeds the maximum permissible concentration of uranium in water by 15 times. If water body is not used for drinking water supply, the calculated concentration of 238U in water producing the annual dose to population 1 mSv, is higher than the maximum permissible concentration of uranium in water by 1500 times. The restrictions imposed by the current hygienic standards for the chemical toxicity of uranium could reduce the permissible discharge levels of 238U to surface waters. It is necessary to develop environmental quality standards for 238U, taking into account its chemical toxicity, and include them to the system of establishment of permissible discharge limits of radioactive substances.

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