scholarly journals The Association of Prenatal Exposure to Perfluorinated Chemicals with Maternal Essential and Long-Chain Polyunsaturated Fatty Acids during Pregnancy and the Birth Weight of Their Offspring: The Hokkaido Study

2015 ◽  
Vol 123 (10) ◽  
pp. 1038-1045 ◽  
Author(s):  
Reiko Kishi ◽  
Tamie Nakajima ◽  
Houman Goudarzi ◽  
Sachiko Kobayashi ◽  
Seiko Sasaki ◽  
...  
2001 ◽  
Vol 73 (3) ◽  
pp. 489-500 ◽  
Author(s):  
J.A. Rooke ◽  
A.G. Sinclair ◽  
S.A. Edwards ◽  
R. Cordoba ◽  
S. Pkiyach ◽  
...  

AbstractSalmon oil (16·5 kg /t), a source of long-chain polyunsaturated n-3 fatty acids, was included in diets offered to multiparous sows during pregnancy and lactation to measure responses in pre-weaning mortality and performance of piglets in two studies. The first study, carried out under commercial conditions, included 196 sows which were offered salmon oil and control diets from immediately post service until weaning. The same diets were also offered to 10 sows per treatment from day 58 of pregnancy in a controlled nutritional study which measured the effects of salmon oil on piglet tissue fatty acid composition. Offering salmon oil to the sow significantly increased gestation length and decreased individual piglet birth weight but had no effect on litter size at birth. Overall, salmon oil reduced pre-weaning mortality from 11·7% to 10·2% mainly by reducing the incidence of deaths from crushing by the sow. More detailed analysis of mortality using a general linear mixed model and 2294 piglet records, demonstrated that the incidence of pre-weaning mortality was significantly decreased with increasing individual piglet birth weight and by inclusion of salmon oil in the diet; the incidence of mortality increased with average piglet birth weight in a litter. Salmon oil inclusion had no effect on weight of litter weaned, sow lactation food intake or subsequent reproductive performance. In both studies, dietary salmon oil increased the proportions of long-chain n-3 polyunsaturated fatty acids in colostrum to a similar extent. In the nutritional study, inclusion of salmon oil reduced the proportions of 20: 4 n-6 in piglet liver and brain at birth and increased the proportions of long-chain n-3 polyunsaturated fatty acids. Therefore, despite reducing piglet birth weight, offering sows salmon oil reduced pre-weaning mortality of piglets. The nutritional study showed that the amount and type of marine oil used may not have been optimal.


2015 ◽  
Vol 2015 (1) ◽  
pp. 961
Author(s):  
Houman Goudarzi ◽  
Reiko Kishi ◽  
Tamie Nakajima ◽  
Sachiko Kobayashi ◽  
Chihiro Miyashita ◽  
...  

2011 ◽  
Vol 217 (1) ◽  
pp. 286-291 ◽  
Author(s):  
Idoia Labayen ◽  
Luis A. Moreno ◽  
Jonatan R. Ruiz ◽  
Francisco B. Ortega ◽  
Michael Sjostrom ◽  
...  

2020 ◽  
Author(s):  
A Lehner ◽  
K Staub ◽  
L Aldakak ◽  
P Eppenberger ◽  
F Rühli ◽  
...  

Abstract Introduction The omega-3 long-chain polyunsaturated fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are important for brain development and cognitive performance. Because they are semi-essential fatty acids, they must be obtained from food. However, the dietary reference intakes of DHA and EPA have not yet been established. In women, a low DHA and/or EPA serum level during pregnancy or breastfeeding might negatively affect their children. For this study, we conducted a systematic review and meta-analysis of randomized control trials on the association between the consumption of fish oil supplements in pregnant and/or breastfeeding women and the cognitive performance of their children. Methods The PubMed, Embase, and Central literature databases were systematically searched. We included and extracted relevant studies in duplicate and assessed study quality. Cognitive outcomes were grouped according to published criteria and according to time elapsed after the intervention. We performed fixed-effects meta-analyses for each cognitive outcome and for birth weight. We assessed potential confounding with meta-regressions and sensitivity analyses. Results A total of 11 trials were included. No significant association was found between DHA/EPA supplementation and any of the assessed cognitive parameters or birth weight. Discussion Our results confirm previous reviews on the studied topic. Reasons for inconclusive results may be small sample sizes for each assessed category, questionable quality of included studies, and the difficulty of reliably measuring cognitive performance in small children. Blood levels of omega-3 long-chain polyunsaturated fatty acids were mostly not comparable. Furthermore, the influence of genetic and environmental factors could not be assessed. Studies in this field should address such shortcomings.


Lipids ◽  
1992 ◽  
Vol 27 (11) ◽  
pp. 896-900 ◽  
Author(s):  
M. T. Clandinin ◽  
M. L. Garg ◽  
A. Parrott ◽  
J. Van Aerde ◽  
A. Hervada ◽  
...  

2006 ◽  
Vol 60 (4) ◽  
pp. 485-489 ◽  
Author(s):  
Silvia Scaglioni ◽  
Elvira Verduci ◽  
Michela Salvioni ◽  
Maria Luisa Biondi ◽  
Giovanni Radaelli ◽  
...  

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