scholarly journals Effects of Maternal Exposure to Di-(2-ethylhexyl) Phthalate during Fetal and/or Neonatal Periods on Atopic Dermatitis in Male Offspring

2008 ◽  
Vol 116 (9) ◽  
pp. 1136-1141 ◽  
Author(s):  
Rie Yanagisawa ◽  
Hirohisa Takano ◽  
Ken-ichiro Inoue ◽  
Eiko Koike ◽  
Kaori Sadakane ◽  
...  
Chemosphere ◽  
2019 ◽  
Vol 225 ◽  
pp. 765-774 ◽  
Author(s):  
Jianfeng Feng ◽  
Shaomin Chen ◽  
Youjin Wang ◽  
Qunxing Liu ◽  
Mengqi Yang ◽  
...  

Toxicology ◽  
2006 ◽  
Vol 228 (1) ◽  
pp. 85-97 ◽  
Author(s):  
Anderson J.M. Andrade ◽  
Simone W. Grande ◽  
Chris E. Talsness ◽  
Christine Gericke ◽  
Konstanze Grote ◽  
...  

2021 ◽  
Vol 42 (4) ◽  
pp. e116-e125 ◽  
Author(s):  
Minyoung Jung ◽  
Min-Ji Kim ◽  
Seonwoo Kim ◽  
Yechan Kyung ◽  
Minji Kim ◽  
...  

Background: The association between prenatal exposure to phthalate and childhood atopic dermatitis (AD) has previously been investigated; however, the results are inconsistent. Objective: We aimed to perform a systematic review and meta-analysis of birth cohort studies to investigate whether prenatal exposure to phthalate increases the risk of developing AD in children. Methods: We performed an electronic search of medical literature data bases. Studies were critically appraised, and a meta-analysis was performed. Results: Among 129 articles identified, 11 studies met the eligibility criteria. Included studies originated from Europe (n = 5), the United States (n = 4), and Asia (n = 2). The study sample size ranged from 147 to 1024 mother-child pairs. Quality assessment by using the Newcastle‐Ottawa scale of all the studies had scores of ≥6. A meta-analysis of data from eight selected studies suggested that monobenzyl phthalate (MBzP) exposure was significantly associated with the risk of AD development (odds ratio 1.16 [95% confidence interval, 1.04−1.31]; I2 = 17.36%). However, AD development was not associated with other phthalate metabolites, such as mono-(2-ethylhexyl) phthalate, monoethyl phthalate, mono-isobutyl phthalate, mono-n-butyl phthalate, and the sum of di-[2-ethylhexyl] phthalate on the development of AD (all p values were > 0.05). Conclusion: Our meta-analysis suggested that prenatal exposure to phthalates may be associated with the development of childhood AD. However, further research is needed because only MBzP showed statistical significance and the number of articles in the literature is still insufficient.


2008 ◽  
Vol 179 (4S) ◽  
pp. 97-98
Author(s):  
John J DeCaro ◽  
Chanley M Small ◽  
Metrecia L Terrell ◽  
Celia E Dominguez ◽  
Lorraine L Cameron ◽  
...  

2020 ◽  
Vol 144 ◽  
pp. 111603 ◽  
Author(s):  
Efrosini S. Katsanou ◽  
Petros Batakis ◽  
Anastasia Spyropoulou ◽  
Elga Schreiber ◽  
Toine Bovee ◽  
...  

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