scholarly journals Editorial: The 13th Rothkopf Rankings: All-Time Interfaces/INFORMS Journal on Applied Analytics 50-Year Anniversary Special Edition

2020 ◽  
Vol 50 (6) ◽  
pp. 387-395
Author(s):  
Michael F. Gorman

In 1996, Michael Rothkopf created an index of institutional contributions to the practice of operations research (OR) and management science (MS). Since then, Ron Fricker and I have continued to calculate, evolve, and extend this ranking. In this Interfaces (INT) and INFORMS Journal on Applied Analytics (IJAA) anniversary ranking, I analyze organizational contributions to the practice of OR/MS in INT since the inception of the journal in 1971. I calculate all three prior ranking measures—visibility, yield, and academic yield—and a blend of the rankings. This analysis considers only articles in INT/IJAA, which is a departure from prior rankings, which included applied work in some other journals. However, for the first time, we have a single database of every article ever published in INT/IJAA, allowing analysis of trends over time. I am also able to compute the all-time contributions of nonacademic institutions as done by Fricker in 2012.

Cliometrica ◽  
2021 ◽  
Author(s):  
Facundo Alvaredo ◽  
A. B. Atkinson

AbstractThere have been important studies of recent income inequality and of poverty in South Africa, but very little is known about the long-run trends over time. There is speculation about the extent of inequality when the Union of South Africa was formed in 1910, but no hard evidence. In this paper, we provide evidence that is partial—being confined to top incomes—but which for the first time shows how the income distribution changed on a (near) annual basis from 1913 onwards. We present estimates of the shares in total income of groups such as the top 1% and the top 0.1%, covering the period from colonial times to the twenty-first century. For a number of years during the apartheid period, we have data classified by race. The estimates for recent years bear out the picture of South Africa as a highly unequal country, but allow this to be placed in historical and international context. The time series presented here will, we hope, provide the basis for detailed investigation of the impact of South African institutions and policies, past and present. But the similarity of the changes over time in top incomes across the four ex-dominions suggests that national developments have to be seen in the light of common global forces.


Author(s):  
Manuel Fröhlich ◽  
Abiodun Williams

The Conclusion returns to the guiding questions introduced in the Introduction, looking at the way in which the book’s chapters answered them. As such, it identifies recurring themes, experiences, structures, motives, and trends over time. By summarizing the result of the chapters’ research into the interaction between the Secretaries-General and the Security Council, some lessons are identified on the changing calculus of appointments, the conditions and relevance of the international context, the impact of different personalities in that interaction, the changes in agenda and composition of the Council as well as different formats of interaction and different challenges to be met in the realm of peace and security, administration, and reform, as well as concepts and norms. Taken together, they also illustrate the potential and limitations of UN executive action.


2020 ◽  
Vol 13 ◽  
pp. 175628482093518 ◽  
Author(s):  
Angélique Saint ◽  
Maxime Benchetrit ◽  
Sébastien Novellas ◽  
Denis Ouzan ◽  
Alexander Tuan Falk ◽  
...  

Introduction: Hepatocholangiocarcinoma (HCC-ICC) is a rare tumor presenting the histologic characteristics of both hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). As there is no consensus on it management, the therapeutic strategy rests on the specific treatments for HCC or ICC. Programmed cell death 1 (PD-1) inhibitors showed encouraging results in the second line treatment of HCC after sorafenib but it efficacy in HCC-ICC has never been reported. Methods and results: We present the case of a 72-year-old male patient treated for metastatic HCC-ICC due to a viral hepatitis C cirrhosis in progression after two lines of treatment. Tumor was characterized by a PDL-1 status of 85%. Patient received pembrolizumab at doses of 200 mg every 21 days by intravenous infusion. After one injection he was presented an immediate clinical benefit, a partial response was observed after two months of treatment and a complete response two months later. This response was maintained over time along with toxicity-free tumor control after 18 months treatment. Conclusion: To our knowledge, we reported for the first time the efficacy of a PD1 inhibitor treatment in a patient presenting metastatic HCC-ICC due to viral cirrhosis and overexpressing PDL-1 after failure of two lines of treatment.


2015 ◽  
Vol 138 (3) ◽  
pp. 536-541 ◽  
Author(s):  
Jamie Kroft ◽  
Qing Li ◽  
Refik Saskin ◽  
Laurie Elit ◽  
Marcus Q. Bernardini ◽  
...  

2017 ◽  
Vol 7 ◽  
pp. 46-49 ◽  
Author(s):  
Michael F. Pesko ◽  
Johanna Catherine Maclean ◽  
Cameron M. Kaplan ◽  
Steven C. Hill

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