Prevalence of Vitamin D Deficiency among Saudi Depressed Patients : A Hospital Record - Based Study

2020 ◽  
Vol 7 (3) ◽  
pp. 13-20
Author(s):  
Rashwan , Eman K. ◽  
Ghazy , Amany A. ◽  
Al Huwaydi , Ahmed M. ◽  
Alsabilah , Raghad Faris ◽  
Alshammari , Reem Obaid ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Hospital Record ◽  
Depressed Patients

The Effect of 2 Different Single Injections of High Dose of Vitamin D on Improving the Depression in Depressed Patients With Vitamin D Deficiency

2013 ◽  
Vol 33 (3) ◽  
pp. 378-385 ◽  
Author(s):  
Hassan Mozaffari-Khosravi ◽  
Lale Nabizade ◽  
Seyed Mojtaba Yassini-Ardakani ◽  
Hossein Hadinedoushan ◽  
Kazem Barzegar
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
High Dose ◽  
Depressed Patients

scholarly journals DEPRESSIVE SYMPTOMS

2015 ◽  
Vol 22 (10) ◽  
pp. 1327-1335
Author(s):  
Saba Irfan ◽  
M. H Qazi
Keyword(s):  
Vitamin D ◽  
Depressive Symptoms ◽  
Depressive Disorder ◽  
Vitamin D Deficiency ◽  
Severe Depression ◽  
Depression Symptoms ◽  
Severity Of Disease ◽  
Depressed Patients ◽  
Increased Risk ◽  
Vitamin D Levels

Introduction: Depression is a leading source of disability world-wide withprevalence ranging from 8.8% to 18.3% in people aged 60 years or older. Depression is a not asimple term but has been used to describe a variety of infirmities, ranging from minor to debilitating.It is a multi-symptom disease and can even lead to suicidal attempt. Major depressive disorder(MDD), although one of the most common psychiatric illnesses, has an unknown etiology.Decreased serum levels of vitamin D have been implicated in the pathogenesis of MDD. Casecontrol studies have supported a relationship between low vitamin D as possible predictorsof depression. We designed a study to determine relationship, if any, between low vitaminD deficiency with depression and with severity of disease in our local population. Objective:The aim of this study to see any association of vitamin D deficiency in depressed Pakistanipatients. Study Design: Cross-sectional study. Setting: Fatima Memorial Hospital, Shadman,Lahore. Period: 2013-2015. Methods: Total of 150 diagnosed patients of 18-75 years of agewas enrolled for this study, after a written consent. Depressed patients were further categorizedinto three groups depending on severity of disease i.e.; mild, moderate and severely depressedpatients. Blood measures included serum vitamin D levels and data was recorded on structureddata collection form. Results: In this study, we investigated the association between vitamin Dstatus and depression in our local Pakistani population. Out of 150 depressed patients, 84.7%were vitamin D deficient. In our study, Out of 44 male depressed patients 9 (20.5%) had milddepression, 8 (18.2%) had moderate depression and 27 (61.4%) had severe depression. Outof 106 depressed female patients 42 (39.6%) had mild depression, 26 (24.5%) had moderatedepression and 38 (35.8%) had severe depression symptoms. A negative correlation of vitaminD with severity of disease was also found in female depressed patients in our study.A significantnegative correlation of vitamin D in all 44 male subjects with severity of disease was observedin our study. Higher prevalence of vitamin D deficiency was found in both males and females inour study. Conclusions: Vitamin D deficiency is associated with an increased risk of developingdepression, but more prospective observational studies may be needed. Efficacy of vitamin Dsupplementation for preventing onset of depressive disorder is unknown. Efficacy of vitamin Dsupplementation for reducing depressive symptoms is largely unstudied. The study suggestsdietary intervention with vitamin D would boost brain serotonin concentrations and help preventand possibly relieve some of the symptoms associated with depression without side effects.

Vitamin D Deficiency

2011 ◽  
Vol 44 (14) ◽  
pp. 22
Author(s):  
WILLIAM E. GOLDEN ◽  
ROBERT H. HOPKINS
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency

Abstract #1236: The Blood Turnover Markers and Parathormon Levels in Menopausal Women with Vitamin D Deficiency

2015 ◽  
Vol 21 ◽  
pp. 293-294
Author(s):  
Mara Carsote ◽  
Cristina Capatina ◽  
Alexandra Mihai ◽  
Andreea Geleriu ◽  
Rodica Petris ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Menopausal Women ◽  
Turnover Markers

Vitamin D3 supplementation improves glycemic control in type 2 diabetic patients: Results from an Italian clinical trial

2020 ◽  
pp. 1-10
Author(s):  
Giuseppe Derosa ◽  
Angela D’Angelo ◽  
Chiara Martinotti ◽  
Maria Chiara Valentino ◽  
Sergio Di Matteo ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Metabolic Control ◽  
Vitamin D3 ◽  
Therapy Group ◽  
Hypoglycemic Agents ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Abstract. Background: to evaluate the effects of Vitamin D3 on glyco-metabolic control in type 2 diabetic patients with Vitamin D deficiency. Methods: one hundred and seventeen patients were randomized to placebo and 122 patients to Vitamin D3. We evaluated anthropometric parameters, glyco-metabolic control, and parathormone (PTH) value at baseline, after 3, and 6 months. Results: a significant reduction of fasting, and post-prandial glucose was recorded in Vitamin D3 group after 6 months. A significant HbA1c decrease was observed in Vitamin D3 (from 7.6% or 60 mmol/mol to 7.1% or 54 mmol) at 6 months compared to baseline, and to placebo (p < 0.05 for both). At the end of the study period, we noticed a change in the amount in doses of oral or subcutaneous hypoglycemic agents and insulin, respectively. The use of metformin, acarbose, and pioglitazone was significantly lower (p = 0.037, p = 0.048, and p = 0.042, respectively) than at the beginning of the study in the Vitamin D3 therapy group. The units of Lispro, Aspart, and Glargine insulin were lower in the Vitamin D3 group at the end of the study (p = 0.031, p = 0.037, and p = 0.035, respectively) than in the placebo group. Conclusions: in type 2 diabetic patients with Vitamin D deficiency, the restoration of value in the Vitamin D standard has led not only to an improvement in the glyco-metabolic compensation, but also to a reduced posology of some oral hypoglycemic agents and some types of insulin used.

Clinical factors correlated with vitamin D deficiency in patients with obesity scheduled for bariatric surgery: A single center experience

2020 ◽  
Vol 90 (3-4) ◽  
pp. 346-352
Author(s):  
Vincenzo Pilone ◽  
Salvatore Tramontano ◽  
Carmen Cutolo ◽  
Federica Marchese ◽  
Antonio Maria Pagano ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Inverse Correlation ◽  
Model Assessment ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Female Sex ◽  
Vitamin D Levels

Abstract. We aim to assess the prevalence of vitamin D deficiency (VDD) in patients scheduled for bariatric surgery (BS), and to identify factors that might be associated with VDD. We conducted a cross-sectional observational study involving all consecutive patients scheduled for BS from 2017 to 2019. The exclusion criteria were missing data for vitamin D levels, intake of vitamin D supplements in the 3 months prior to serum vitamin D determination, and renal insufficiency. A total of 206 patients (mean age and body mass index [BMI] of 34.9 ± 10.7 years, and 44.3 ± 6.99 kg/m2, respectively) met the inclusion criteria and were enrolled for data analysis. VDD (<19.9 ng/mL), severe VDD (<10 ng/mL), and vitamin D insufficiency (20–29.9 ng/mL) were present in 68.8 %, 12.5 %, and 31.2 % of patients, respectively. A significant inverse correlation was found between vitamin D levels and initial BMI, parathyroid hormone, and homeostatic model assessment of insulin resistance (r = −0.280, p < 0.05; r = −0.407, p = 0.038; r = −0.445, p = 0.005), respectively. VDD was significantly more prevalent in patients with higher BMI [−0.413 ± 0.12, CI95 % (−0.659; −0.167), p = 0.006], whereas no significant association between hypertension [−1.005 ± 1.65, CI95 % (−4.338; 2.326), p = 0.001], and diabetes type 2 (T2D) [−0.44 ± 2.20, CI95 % (−4.876; 3.986), p = 0.841] was found. We observed significant association between female sex and levels of vitamin D [6.69 ± 2.31, CI95 % (2.06; 11.33), p = 0.006]. The present study shows that in patients scheduled for BS, VDD deficiency is common and was associated with higher BMI, and female sex.

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