Studying Depression Status and Possible Association with Vitamin D Deficiency and the Level of Thyroid Stimulating Hormone among Jordanian Patients with Addiction

2019 ◽  
Vol 26 (1) ◽  
pp. 31-36
Author(s):  
Maher , Alasasleh ◽  
Bashir , Nabil A. ◽  
Alkhatib , Ahed J. ◽  
Alomary , Mohammadnoor ◽  
Aburumman , Raafat
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Thyroid Stimulating Hormone ◽  
Depression Status ◽  
Stimulating Hormone

scholarly journals “Vitamin D Deficiency Is More Common in Women with Autoimmune Thyroiditis: A Retrospective Study”

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Nino Turashvili ◽  
Lali Javashvili ◽  
Elene Giorgadze
Keyword(s):  
Vitamin D ◽  
Retrospective Study ◽  
Vitamin D Deficiency ◽  
Autoimmune Thyroiditis ◽  
Thyroid Stimulating Hormone ◽  
Primary Hypothyroidism ◽  
Thyroid Autoantibody ◽  
Chronic Autoimmune Thyroiditis ◽  
Antithyroglobulin Antibodies ◽  
Stimulating Hormone

Background. Vitamin D is a hormone that is mainly produced in the skin upon ultraviolet B radiation exposure and has important influence on various organs. In recent years, data have been collected that vitamin D deficiency plays an important role in the development of various nonskeletal diseases, including autoimmune diseases. Chronic autoimmune thyroiditis (Hashimoto’s thyroiditis) is one of the most common organ-specific autoimmune endocrine diseases. It is characterized by increased level of antithyroid peroxidase and/or antithyroglobulin antibodies in blood, which often leads to thyroid dysfunction and structural changes of the gland. There is an opinion that vitamin D deficiency may be considered as an important risk factor for development of chronic autoimmune thyroiditis, but data of various small studies are controversial. Despite the fact that Georgia is a sunny country, vitamin D deficiency is a widespread problem here. Thyroid diseases, including the chronic autoimmune thyroiditis, are also very common in Georgia. The aim of our research was to compare the level of vitamin D between the patients with chronic autoimmune thyroiditis and the healthy subjects. Methods. This retrospective study enrolled subjects, who were 18–70 years old and visited the clinics “Cortex” and “National Institute of Endocrinology” in 2018 or in 2019 from mid-spring to mid-summer. Data of thyroid-stimulating hormone, free thyroxine, antithyroid peroxidase antibodies, antithyroglobulin antibodies, thyroid ultrasonography, and 25(OH) vitamin D were retrospectively analysed based on medical history. In total, data of 1295 patients were collected. The statistical processing of data was performed through the SPSS 20 program. Results. The negative association between thyroid-stimulating hormone, antithyroid peroxidase antibodies, antithyroglobulin antibodies, heterogeneous parenchyma of thyroid gland, and vitamin D was found in women. Statistically significant association was not detected in men. Conclusions. Serum vitamin D is lower in women with autoimmune thyroiditis and primary hypothyroidism. Further studies are needed to evaluate the influence of vitamin D supplementation on thyroid autoantibody positivity or primary hypothyroidism.

Evaluation of Vitamin D Deficiency and Its Relationship with Body Mass Index in Children 1 To 16 Years

2021 ◽  
Author(s):  
Elham Nozari Mirarkolaei ◽  
Mahdi Gholami ◽  
Elham Rostami ◽  
Azita Aliakbarniya ◽  
Massoumeh Hotelchi ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Vitamin D ◽  
Children And Adolescents ◽  
Vitamin D Deficiency ◽  
Body Mass ◽  
Body Weight Gain ◽  
Thyroid Stimulating Hormone ◽  
Overweight And Obesity ◽  
Mazandaran Province ◽  
Significant Difference

Introduction: Body weight gain in children and teenagers is one of the major challenges that cause undesirable health outcomes. Simultaneously with the prevalence of overweight and obesity, children and adolescents are diagnosed with 25-hydroxyvitamin D (25(OH)D) deficiency in different sides of the world. The present study aimed to assess 25(OH)D status among Iranian volunteers aged 1-16 years and find the correlation between 25(OH)D status and body mass index (BMI) subjects.    Material and Methods: The total volunteers included 807 Iranian children aged 1 to 16 referred to the general and endocrinology clinics in Babol city, Mazandaran Province. A trained physician determined anthropometric characteristics. Serum levels of calcium (Ca), phosphate (P), creatinine (Cr), urea, thyroxine (T4), thyroid-stimulating hormone (TSH), and 25(OH)D were assessed in all children.      Results: 25.27% of the children were 25(OH)D deficient, and 59.1% were insufficient. There was no significant difference in serum 25(OH)D level between girls and boys (P=0.13). A significant negative correlation was found in serum 25(OH)D level with weight (P=0.000, r=-0.12), BMI (P=0.000, r=-0.13), and age (P=0.000, r=-0.13). Conclusion: These data displayed that 25(OH)D insufficiency is highly prevalent among children in the north of Iran. Serum 25(OH)D levels are affected by age and BMI value. Improving vitamin D deficiency helps to maintain the health of children and adolescents during this critical period.

scholarly journals The Effect of Vitamin D Replacement on Patient with Subclinical Hypothyroidism: A Pilot Randomized Clinical Trial

2020 ◽  
Vol 9 ◽  
pp. 1592
Author(s):  
Babak Pezeshki ◽  
Ali Ahmadi ◽  
Aliasghar Karimi
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Subclinical Hypothyroidism ◽  
Serum Levels ◽  
Thyroid Stimulating Hormone ◽  
T Test ◽  
Overt Hypothyroidism ◽  
Paired Samples ◽  
The Difference ◽  
Vitamin D Supplements

Background: Subclinical hypothyroidism (SCH) is characterized by an elevated Thyroid Stimulating Hormone (TSH) with a normal T4. The prevalence of Vitamin D deficiency in patients SCH is high. Some studies suggested that Vitamin D supplements could be reduced serum concentration of TSH so improve SCH and prevent overt hypothyroidism. This study aims to explore the effect of vitamin D replacement on subclinical hypothyroidism. Materials and Methods: Fifty-nine patients, diagnosed with both subclinical hypothyroidism and Vitamin D deficiency by the Endocrinology outpatient clinics between January 2018 and March 2019, were included in this trial. The patients with overt hypothyroidism, cardiovascular risk factors, or positive TPO antibody, abnormal T4, and pregnant women were excluded from this study. The 40 subjects were investigated who received vitamin D supplements for two months.  Analyses were conducted through paired-samples t-test and independent-samples t-test using SPSS 24 (Armonk, NY: IBM Corp). Results: The mean serum levels of TSH was decreased from 6.89 mIU/l in the pre-test to 3.34 mIU/l in the post-test, and the difference was found to be statistically significant at P<0.001. Conclusion: We found that the TSH mean level significantly dropped through the use of vitamin D supplements. Thus, it is recommended that all the patients with subclinical hypothyroidism be screened and treated with vitamin D supplements. [GMJ.2020;9:e1592]

scholarly journals Efficacy of Vitamin-D Supplement on Thyroid Profile in Children with Graves’ Disease

2020 ◽  
Vol 8 (B) ◽  
pp. 798-801
Author(s):  
Winra Pratita ◽  
Karina Sugih Arto ◽  
Nindia Sugih Arto
Keyword(s):  
Vitamin D ◽  
Thyroid Hormone ◽  
Vitamin D Deficiency ◽  
Thyroid Disease ◽  
Vitamin D Supplementation ◽  
Thyroid Stimulating Hormone ◽  
Graves Disease ◽  
Vitamin D Levels ◽  
Thyroid Profile ◽  
Vitamin D Supplement

BACKGROUND: Many studies have shown low Vitamin-D level as a risk factor for autoimmune diseases, especially multiple sclerosis and thyroid disease. Graves’ disease (GD) is an autoimmune disease caused by autoantibodies that stimulate thyroid-stimulating hormone (TSH) receptors by increasing thyroid hormone synthesis and secretion. Several studies report that many patients with autoimmune thyroid disease including GD have low Vitamin-D status. AIM: The objective of the study was to evaluate the effect of Vitamin-D supplement on GD patients on improvement in thyroid hormone levels. METHODS: Open random clinical trial was conducted in GD patients to determine changes in thyroid hormone to achieving normal levels between those receiving methimazole plus Vitamin-D supplementation compared with those who only received methimazole. Patients were checked for TSH receptor antibody, thyroid profile and Vitamin-D level before treatment and rechecked for thyroid profile and Vitamin-D level 3 months after treatment. t-test used to compare the drug efficacy (p < 0.05) in two groups. RESULTS: From 25 children with GD accompanied by Vitamin-D deficiency with an average value of Vitamin-D was 16 ng/mL. GD children who receive methimazole with Vitamin-D supplement had elevated TSH levels in the 3rd month of therapy that was significantly different compared to GD children who received methimazole only (p = 0.00), and the increase of TSH was also followed by an increase in Vitamin-D levels. CONCLUSION: All children with GD had Vitamin D deficiency, and the addition of Vitamin-D supplement to GD therapy would improve TSH faster than children who did not receive Vitamin-D supplement.

scholarly journals The Effectiveness of Pilates Training and Vitamin D Intake on the hs-CRP and TSH in Overweight Men

2021 ◽  
Vol 25 (1) ◽  
pp. 31-38
Author(s):  
Fatemeh Ebrahemi Rokni ◽  
◽  
Masoumeh Habibian ◽  
Saqqa Farajtabar Behrestaq ◽  
◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Thyroid Function ◽  
Systemic Inflammation ◽  
High Sensitivity ◽  
Thyroid Stimulating Hormone ◽  
Vitamin D Intake ◽  
Hs Crp ◽  
Combined Intervention ◽  
Tsh Levels

Background: Vitamin D deficiency is known as a risk factor for various diseases and plays an important role in regulating systemic inflammation and thyroid function. Objective: The study was done to survey the effectiveness of Pilates training and vitamin D intake on serum high-sensitivity C-reactive protein (hs-CRP) and Thyroid-Stimulating Hormone (TSH) levels in overweight men. Methods: This clinical trial was conducted on 50 overweight men aged 45-55 years. Subjects were selected through available sampling and randomly assigned to the Pilates training, Pilates training with vitamin D, vitamin D, and control groups. The Pilates training was performed for eight weeks with the intensity of 50%-75% of reserve heart rate in 3 sessions/week. The supplement groups received 50000IU vitamin D weekly. The levels of hs-CRP and TSH were measured at first and eighth weeks after interventions. The data were analyzed by paired t-test and one-way ANOVA (p˂0.05). Findings: The results showed that 60% and 40% of the subjects had a vitamin D deficiency and insufficiency, respectively. Also, eight weeks of Pilates training, vitamin D intake, and the combined intervention resulted in a significant decrease in hs-CRP and TSH levels (p<0.05). Also, the combined intervention was associated with a stronger effect on the reduction of these factors compared with two other interventions (p˂0.05). Conclusion: It seems that abnormal levels of vitamin D are common in overweight men and vitamin D intake, Pilates training, and the combination can improve thyroid function and systemic inflammation in overweight men with abnormal vitamin D status. However, the combined intervention is associated with stronger effects.

VITAMIN D AND THYROID HORMONES IN PATIENTS WITH BREAST BENIGN TUMOR

2021 ◽  
Author(s):  
SALOME GLONTI ◽  
RUSUDAN VADACHKORIA ◽  
JUMBER UNGIADZE
Keyword(s):  
Vitamin D ◽  
Thyroid Hormones ◽  
Health Problem ◽  
Breast Tumor ◽  
Benign Tumor ◽  
Thyroid Stimulating Hormone ◽  
Control Group ◽  
Breast Health ◽  
Free Triiodothyronine ◽  
Stimulating Hormone

The Breast Benign tumor (BBT) is currently considered a significant breast health problem within women of all ages. In the present study, we aimed to investigate the Tumor markers CA125 and CA153, thyroid hormones free triiodothyronine (FT3), free thyroxine (FT4), thyroid-stimulating hormone (TSH), and vitamin D within benign breast tumor (BBT) during the reproduction ages. Twenty patients (ten patients in the control group and ten patients in cases (Breast Benign Tumor); Notably, the studies confirm the decrease in FT4 and FT3 and increase of the thyroid-stimulating hormone (TSH). In addition, the decreased level of Vitamin D is also revealed in BBT.

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