Efficacy of Sublingual Immunotherapy versus Subcutaneous Immunotherapy in Treatment of Children with Grass Pollen Induced Vernal Keratoconjunctivitis by Eosinophilic Cationic Protien

2017 ◽  
Vol 26 (3) ◽  
pp. 119-130
Author(s):  
Randa S. Abdel-Latif ◽  
Basem M. Ibrahim
Keyword(s):  
Grass Pollen ◽  
Sublingual Immunotherapy ◽  
Vernal Keratoconjunctivitis ◽  
Subcutaneous Immunotherapy

Efficacy of sublingual immunotherapy tablets in dust mite and pollen allergy

2021 ◽  
Vol 42 (1) ◽  
pp. 36-42 ◽  
Author(s):  
Yuriy Bisyuk ◽  
Ilona DuBuske ◽  
Lawrence M. DuBuske
Keyword(s):  
T Cells ◽  
Comparative Analysis ◽  
Grass Pollen ◽  
Sublingual Immunotherapy ◽  
Pollen Allergy ◽  
Subcutaneous Immunotherapy ◽  
Efficacy And Safety ◽  
Dust Mite ◽  
Timothy Grass Pollen ◽  
New Biomarkers

The latest evidence on the mechanisms, efficacy, and safety of sublingual immunotherapy (SLIT) was reviewed. Interleukin (IL) 35 and IL-35‐producing regulatory T cells were assessed as new biomarkers for SLIT responsiveness. A detailed analysis of clinical studies, including timothy grass pollen, 5-grass pollen, ragweed, and house-dust mite SLIT tablets, was provided, including a comparative analysis of efficacy and safety of SLIT versus subcutaneous immunotherapy.

Safety of sublingual grass pollen immunotherapy after anaphylaxis

2008 ◽  
Vol 123 (6) ◽  
pp. 683-684 ◽  
Author(s):  
J R Nichani ◽  
J de Carpentier
Keyword(s):  
Case Report ◽  
Adverse Events ◽  
Grass Pollen ◽  
Side Effect ◽  
Sublingual Immunotherapy ◽  
Subcutaneous Immunotherapy ◽  
Side Effect Profile ◽  
Fatal Complication ◽  
Discontinuation Of Treatment ◽  
Safe Treatment Option

AbstractAim:To demonstrate that sublingual immunotherapy is a safe treatment option in patients who have previously suffered anaphylaxis when undergoing subcutaneous grass pollen immunotherapy.Case report:We report two patients who developed a systemic anaphylactic reaction following subcutaneous grass pollen immunotherapy, resulting in discontinuation of treatment. Following treatment of the acute anaphylactic episode, both patients were subsequently safely commenced on sublingual grass pollen immunotherapy.Conclusion:Injection immunotherapy has a relatively low risk of severe adverse events, although anaphylaxis is a potentially fatal complication and usually results in termination of the immunotherapy programme. Sublingual immunotherapy has a safer side effect profile than subcutaneous immunotherapy, with no reported cases of anaphylaxis.

scholarly journals Plant Food Allergy Improvement after Grass Pollen Sublingual Immunotherapy: A Case Series

Pathogens ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1412
Author(s):  
Fabiana Furci ◽  
Luisa Ricciardi
Keyword(s):  
Food Allergy ◽  
Grass Pollen ◽  
Sublingual Immunotherapy ◽  
Case Series ◽  
Food Allergies ◽  
Subcutaneous Immunotherapy ◽  
Pollen Extract ◽  
Plant Food ◽  
Good Tolerance ◽  
Sublingual Tablet

Background: Cross-reactivity between pollens and plant food has been widely described. Pollen extract subcutaneous immunotherapy in patients with pollens and plant food allergy has been shown to improve tolerance not only to inhalant allergens but also to reduce symptoms in patients with various food allergies. Methods: We retrospectively report our experience with 15 female patients with a positive history for moderate, persistent allergic rhinitis due to grass pollen and oropharyngeal symptoms after ingestion of different plant food. These patients followed a five-grass pollen sublingual tablet immunotherapy for three years in a discontinuous pre-co-seasonal scheme. Results: All 15 patients treated with the 5-grass pollen sublingual tablet immunotherapy, taken once daily for 3 years on a 7-month course, showed improved ocular/nasal symptoms, with a reduction in the use of symptomatic drugs (e.g., nasal corticosteroids and H1 antihistamines). After the first seven-month course of immunotherapy, all patients declared a good tolerance to the intake of fruits and vegetables, and in particular, good tolerance to the offending foods. Conclusions: In conclusion, we have observed improvement of both respiratory and plant food allergies after sublingual immunotherapy (SLIT) with a five-grass pollen tablet.

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