Autogenous Block Onlay Bone Graft versus Xenogenic Cortical Bone Lamina in Alveolar Ridge Augmentation : A Clinical , Radiographic and Histological Evaluation

2014 ◽  
Vol 17 (2) ◽  
pp. 71-78
Author(s):  
Ahmed Amr Thoria ◽  
Khaled Atef Abd El-Ghaffar ◽  
Hala Ahmed Abuel-Ela
Keyword(s):  
Bone Graft ◽  
Cortical Bone ◽  
Histological Evaluation ◽  
Alveolar Ridge ◽  
Alveolar Ridge Augmentation ◽  
Ridge Augmentation

scholarly journals Comparison of Calcium Sulfate and Bovine Collagen Barriers for Alveolar Ridge Augmentation

2014 ◽  
Vol 4 (3) ◽  
pp. 129-138
Author(s):  
Robert Spears ◽  
Ibtisam Al-Hashimi ◽  
Eric S Solomon ◽  
David G Kerns ◽  
William W Hallmon ◽  
...  
Keyword(s):  
Bone Graft ◽  
Calcium Sulfate ◽  
Autogenous Bone ◽  
Collagen Membrane ◽  
Alveolar Ridge ◽  
Bone Augmentation ◽  
Alveolar Ridge Augmentation ◽  
Ridge Augmentation ◽  
Bovine Collagen ◽  
Bone Gain

ABSTRACT Calcium sulfate is a biologically compatible osteoconductive graft material that binds underlying bone graft and provide space maintenance. The purpose of this study was to evaluate calcium sulfate as a barrier compared to a collagen membrane for augmentation of a standardized surgically created ridge defect. For this purpose, bilateral extraction of mandibular premolars was performed on six foxhounds (Canis familiaris). Eight weeks later, a standardized osseous ridge defects (24 total) were created using a 6 mm trephine. The study was approved by the Institutional Animal Care and Use Committee (IACUC) at Baylor College of Dentistry. The osseous defects were allocated into three groups (8 defects each): group 1 received autogenous bone graft covered with collagen membrane (CM); group 2 received autogenous bone graft covered with calcium sulfate barrier (CS), and group 3 was used as control and did not receive bone augmentation and was used as control. The animals were sacrificed after 12 weeks following bone augmentation and sites were evaluated histologically for total ridge width, percentage of bone gain and cortical bone thickness. Results All sites exhibited bony fill within the defect. Analysis of variance did not reveal statistically significant difference in the mean total bone gain among CM, CS, and control groups (12.2,11.6, and 11.9) mm2, respectively, p = 0.875. Conclusion Calcium sulfate does not appear to improve bone regeneration in an osseous defect. How to cite this article Heaton ML, Kerns DG, Hallmon WW, Kessler HP, Spears R, Solomon ES, Al-Hashimi I. Comparison of Calcium Sulfate and Bovine Collagen Barriers for Alveolar Ridge Augmentation. J Contemp Dent 2014;4(3):129-138.

scholarly journals Human Studies of Vertical and Horizontal Alveolar Ridge Augmentation Comparing Different Types of Bone Graft Materials: A Systematic Review

2018 ◽  
Vol 44 (1) ◽  
pp. 74-84 ◽  
Author(s):  
Suraj Chavda ◽  
Liran Levin
Keyword(s):  
Systematic Review ◽  
Bone Graft ◽  
Case Series ◽  
Human Studies ◽  
Autogenous Bone ◽  
Alveolar Ridge ◽  
Bone Augmentation ◽  
Alveolar Ridge Augmentation ◽  
Ridge Augmentation ◽  
Different Types

Alveolar ridge augmentation can be completed with various types of bone augmentation materials (autogenous, allograft, xenograft, and alloplast). Currently, autogenous bone is labeled as the “gold standard” because of faster healing times and integration between native and foreign bone. No systematic review has currently determined whether there is a difference in implant success between various bone augmentation materials. The purpose of this article was to systematically review comparative human studies of vertical and horizontal alveolar ridge augmentation comparing different types of bone graft materials (autogenous, allograft, xenograft, and alloplast). A MEDLINE search was conducted under the 3 search concepts of bone augmentation, dental implants, and alveolar ridge augmentation. Studies pertaining to socket grafts or sinus lifts were excluded. Case reports, small case series, and review papers were excluded. A bias assessment tool was applied to the final articles. Overall, 219 articles resulted from the initial search, and 9 articles were included for final analysis. There were no discernible differences in implant success between bone augmentation materials. Generally, patients preferred nonautogenous bone sources as there were fewer hospital days, less pain, and better recovery time. Two articles had industrial support; however, conclusions of whether that support influenced the outcomes could not be determined. Future comparative studies should compare nonautogenous bone sources and have longer follow-up times.

scholarly journals Advantage of Alveolar Ridge Augmentation with Bioactive/Bioresorbable Screws Made of Composites of Unsintered Hydroxyapatite and Poly-L-lactide

Materials ◽  
2019 ◽  
Vol 12 (22) ◽  
pp. 3681 ◽  
Author(s):  
Shintaro Sukegawa ◽  
Hotaka Kawai ◽  
Keisuke Nakano ◽  
Kiyofumi Takabatake ◽  
Takahiro Kanno ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Transcription Factor ◽  
Leptin Receptor ◽  
Histological Evaluation ◽  
Bone Block ◽  
Alveolar Ridge ◽  
Alveolar Ridge Augmentation ◽  
Ridge Augmentation

We studied human bone healing characteristics and the histological osteogenic environment by using devices made of a composite of uncalcined and unsintered hydroxyapatite (u-HA) and poly-L-lactide (PLLA). In eight cases of fixation, we used u-HA/PLLA screws for maxillary alveolar ridge augmentation, for which mandibular cortical bone block was used in preimplantation surgery. Five appropriate samples with screws were evaluated histologically and immunohistochemically for runt-related transcription factor 2 (RUNX2), transcription factor Sp7 (Osterix), and leptin receptor (LepR). In all cases, histological evaluation revealed that bone components had completely surrounded the u-HA/PLLA screws, and the bone was connected directly to the biomaterial. Inflammatory cells did not invade the space between the bone and the u-HA/PLLA screw. Immunohistochemical evaluation revealed that many cells were positive for RUNX2 or Osterix, which are markers for osteoblast and osteoprogenitor cells, in the tissues surrounding u-HA/PLLA. In addition, many bone marrow–derived mesenchymal stem cells were notably positive for both LepR and RUNX2. The u-HA/PLLA material showed excellent bioactive osteoconductivity and a highly biocompatibility with bone directly attached. In addition, our findings suggest that many bone marrow–derived mesenchymal stem cells and mature osteoblast are present in the osteogenic environment created with u-HA/PLLA screws and that this environment is suitable for osteogenesis.

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