Demographic Criteria , Clinical Profile and Outcome in Picu of El-Hussein University Hospital

2014 ◽  
Vol 17 (1) ◽  
pp. 93-109
Author(s):  
Ali Mohammed Ali Zaakouk ◽  
Mohamed Abdel Malik Hassan ◽  
Mohammed fathy Hassan
Keyword(s):  
Clinical Profile ◽  
University Hospital

P062 Vasculitis in children: epidemiological, clinical and Para clinical profile in the oriental region of Morocco—about 33 cases

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_5) ◽  
Author(s):  
A Hamami ◽  
A Babakhouya ◽  
A El Ouali ◽  
A Ghannam ◽  
M Rkain ◽  
...  
Keyword(s):  
Pericardial Effusion ◽  
Kawasaki Disease ◽  
Early Diagnosis ◽  
Renal Insufficiency ◽  
Clinical Profile ◽  
Lower Limbs ◽  
University Hospital ◽  
Age Group ◽  
Abdominal Symptoms ◽  
Appropriate Treatment

Abstract Background Vasculitis in children constitute a heterogeneous group of pathologies considered as a rarity in our context and therefore deserves to be better known. Despite their individualization for more than forty years throughout the world, they continue to be a challenging condition both in terms of diagnosis and treatment. The objective of our study is to report the epidemiological profiles of vasculitis and to assess the clinical and Para clinical profile of our patients, in order to contribute to a better knowledge of these conditions in our context, whose early diagnosis allows the starting of an appropriate treatment and the improvement of the prognosis. Material and methods This is a retrospective study, in which we collected data of all children in whom the diagnosis of vasculitis was confirmed, and who were hospitalized in the pediatric department of the University Hospital Center (CHU) Mohamed VI of Oujda over a period of 3 years from July 2014 to July 2017. Results Thirty-three patients were selected; 25 boys (76%) and 8 girls (24%), including 16 patients with Kawasaki disease; 14 patients with Henoch-Schonlein purpura (HSP); 2 patients with Polyarteritis nodosa (PAN); and 1 patient with Takayasu. A male predominance was noted with a sex ratio of 3.16. HSP represented 42.42% of the cases, the most affected age group was between 5 and 9 years in 45% of cases. Purpura was the most frequent symptom (100%) with petechial appearance in 77% of cases and localized in the lower limbs in all cases (100%). Joints were affected in 13 cases (93%), abdominal symptoms were found in 81.82% of cases, with one case of melena and 3 cases of rectal bleeding. The renal symptoms were mainly biological and were dominated by urinary proteinuria (45%), microscopic hematuria in one case, macroscopic hematuria in 3 cases, hypertension in one case and nephrotic syndrome in one case. Five patients developed renal insufficiency, two children had moderate renal insufficiency and three had severe renal insufficiency. Kawasaki disease represented the majority of cases: 16 cases (48.48%), affecting children between 4 and 41 months of age with an average age of 22 months, with most affected age group was between 12 and 24 months in 55%. The appeal signs were multiple dominated by fever which represents 100% of cases, skin rash in 82%, ocular redness in 45%, enanthema in 45%, oedema of the extremities in 45%, and adenopathy in 6% (one case). The inflammatory syndrome was present in all patients. Cardiac Doppler ultrasound was performed in 14 patients. It was abnormal in 22% of cases. 11 patients received a course of IGIV (54.54%), at a dose of 2 g/Kg in a single 12-h infusion. Aspirin was administered in all patients. The evolution was favorable in 15 patients, only one case was complicated by giant aneurysms of both coronaries, which evolved to a slight decrease in size and disappearance of the pericardial effusion. Valvular abnormality was noted in one case and minimal pericardial effusion in one case. Conclusion This study confirmed that incidence of vasculitis in children in our context is average, this can be seen on the non-negligible number of cases (33 cases) collected over a period of 3 years. Early diagnosis of this condition key to allow an initiation of an appropriate treatment and improvement of the prognosis.

scholarly journals Profile and Outcome of Triple Negative Breast Cancer at a Tertiary Care University Hospital in Nepal

2020 ◽  
Vol 5 (2) ◽  
pp. 101-105
Author(s):  
Suman Khanal ◽  
Yogendra P. Singh ◽  
Gita Sayami ◽  
Akihiko Ozaki
Keyword(s):  
Breast Cancer ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Ductal Carcinoma ◽  
Tertiary Care ◽  
Tumor Biology ◽  
Clinical Profile ◽  
University Teaching ◽  
University Hospital ◽  
P Value

Background: TNBC (Triple negative breast cancer) subtype (ER-/PR-/HER2-) of breast cancers are known for aggressive tumor biology and poor survival prospects, with high early relapse rate. However, little is known about the prevalence and characteristics of TNBC breast cancer in Nepal. Objectives: To clarify the geographical distribution, clinical profile and outcome of TNBC patients when compared with non-TNBC patients managed in tertiary care university hospital in Nepal. Materials and Methods: This is a study on prospective observational analyses of TNBC and non-TNBC patients managed at Tribhuvan University Teaching Hospital, Kathmandu from October 2015-March 2018. We collected and analyzed data on clinical profile, pathological tumor features and outcome of the two patient groups. Results: A total of 108 breast cancer patients were included in our study, 38 (35.2%) of which were TNBCs. Mean age at diagnosis was 49±12 years. Majority of TNBCs (29%) were concentrated in Terai districts compared to non-TNBCs (18.6%). Among TNBCs, 15.2% had tumor size 5 cm or more while only 11.9% had such finding in non-TNBCs. Majority of TNBCs and non-TNBCs were of invasive ductal carcinoma of NST histology (76.3 vs 90%). TNBC tumors were significantly of grade 3 (P value=0.003). Perineural invasion was seen more (15.8%) in TNBCs compared to 8.96% in non-TNBCs. On average, 23.6% of total nodes retrieved from axilla were positive for tumor in TNBCs compared to 21% in non-TNBCs. Three patients developed metastases in TNBCs of which two were to brain while 5 had metastases in non-TNBC with none to brain. Higher percentage of patients died in TNBC group (13.2 vs 7.1%). Conclusions: TNBCs are quite common, higher grade tumors with brain metastasis without particular geographic distribution.

scholarly journals 774 Young adults with acute coronary syndrome: still a long road ahead

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Jessica Ielapi ◽  
Salvatore De Rosa ◽  
Giuseppe Deietti ◽  
Claudia Critelli ◽  
Giuseppe Panuccio ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Young Adults ◽  
Myocardial Revascularization ◽  
Young Patients ◽  
Clinical Profile ◽  
University Hospital ◽  
Complete Revascularization ◽  
Percutaneous Coronary Angioplasty ◽  
Coronary Syndrome ◽  
Magna Graecia

Abstract Aims Acute coronary syndrome (ACS) are a leading cause for mortality and morbility worldwide. Despite ACS usually affects the older population, it also occurs in younger individuals. Young ACS patients (YACS) have a significantly worse prognosis compared to their age-mates in the general population. Despite YACS are characterized by a different risk profiles compared to their older mates, many aspects still remain elusive. Aim of this study was to describe the clinical profile of young adults with Acute Coronary Syndrome. Methods and results Young patients (≤50 years) with the first diagnose of Acute Coronary Syndrome admitted to the Magna Graecia University Hospital were enrolled in the ongoing GENEPAMY registry. Over 7 years, a total of 675 eligible patients with Acute Coronary Syndrome aged 44 ± 8 years were included. Men accounted for 84.9% of all patients. Overall, 11.9% of patients had diabetes, 69.1% hypertension, 17.6% obesity, 93.6% dyslipidemia, while 75.5% were smokers. In the overall cohort, 44.1% were first diagnosed with STEMI, 45.9% with NSTEMI, while the remaining had been admitted for Unstable Angina. Cardiogenic shock was present at admission in 2.7% of cases. Multivessel disease was present in 39% of cases and was significantly less frequent in women (P < 0.001). Thrombolysis was administered as the initial treatment in 15.1% of cases but was ineffective in 66.7% of patients. Percutaneous coronary angioplasty was performed in 79.1% of patients, while 1.9% of patients underwent surgical myocardial revascularization. Spontaneous coronary dissection was present in 0.7% of men and 17.2% of women (P < 0.001). At admission, 98.9% of patients had been treated with ASA, 17.9% with clopidogrel, 49.1% with ticagrelor and 28.4% with prasugrel. A complete revascularization was achieved in 81.6% during the index hospitalization but was significantly more frequent in women compared to men (86.3% vs. 80.8; P < 0.001). Conclusions Our data highlight that YACS present a peculiar clinical profile. In particular, the high cardiovascular risk profile demands attention. Finally, despite most patients were men, young women with ACS present several relevant differences compared to men, needing a more careful clinical management.

Clinical Profile of Patients with Acromegaly at Santo Tomas University Hospital

2009 ◽  
Vol 46 (6) ◽  
Author(s):  
Rosario R Bongco ◽  
Honolina S Gomez ◽  
Leilani B Mercado-Asis
Keyword(s):  
Clinical Profile ◽  
University Hospital

Clinical profile of patients hospitalized for delirium

2017 ◽  
Vol 41 (S1) ◽  
pp. S704-S704
Author(s):  
F. Smaoui ◽  
M. Frikha ◽  
I. Bouchhima ◽  
O. Hdiji ◽  
N. Farhat ◽  
...  
Keyword(s):  
Sex Ratio ◽  
Descriptive Study ◽  
Clinical Syndrome ◽  
Clinical Profile ◽  
University Hospital ◽  
First Episode ◽  
Memory Disorder ◽  
The Mean ◽  
Competing Interest ◽  
Medical Histories

IntroductionDelirium is a common clinical syndrome characterized by acute disruption of all cognitive and behavioural functions.Objectives– Draw up an epidemiological and clinical profile of patients hospitalised for delirium;– Assess different pathologies involved.MethodsWe conducted a retrospective and descriptive study, in the neurology department at Habib Bourguiba university hospital, Sfax, Tunisia, at the period from 2009 to 2013. We included 52 patients hospitalised for delirium. Socio-demographic and clinical data were collected from patient files.ResultsThe mean age was 66.5 years. The majority (73.1%) were elderly patients (> = 60 years). Sex-ratio (M/F) was 1.73. It was the first episode in 96.2%.Medical histories were cardiovascular in 55.8%, endocrinal in 25%, neurological in 11.5% and psychiatric in 13.5%. The beginning of the signs was brutal in 55.8% of cases. The reported symptoms were: disorientation in time and space (76.9%) and behaviour disturbance (63.5%), memory disorder (23.1%), headaches (26.9%) and hallucinations (17.3%). Organic etiologies were noted in 75% of cases: vascular 42.30%, metabolic 11.50%, infectious 11.5%, tumoral 3.9% and iatrogenic 3.8%. Delirium grafted on dementia was retained in 5.8% of cases.ConclusionDelirium is associated with increased mortality. Its prevention is essential and requires recognition of risk situations.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Clinical profile of dengue fever infection in King Abdul Aziz University Hospital Saudi Arabia

2010 ◽  
Vol 4 (08) ◽  
pp. 503-510 ◽  
Author(s):  
Maimoona M Ahmed
Keyword(s):  
Dengue Virus ◽  
Dengue Fever ◽  
Clinical Symptoms ◽  
Degradation Products ◽  
Disease Incidence ◽  
Inverse Correlation ◽  
Immunoglobulin M ◽  
Clinical Profile ◽  
Direct Bilirubin ◽  
University Hospital

Background: The study aimed to compare the clinical profile of all patients diagnosed with dengue viral infection at King Abdul Aziz University Hospital (KAAUH), during 2005-2008. Methodology: This retrospective study included 147 patients infected with dengue virus, age ≤ 16 years. Laboratory and haematological data were included. Results: Two peaks of infection occurred during 2006 and another two in 2008. Common clinical symptoms were fever, vomiting, and abdominal pain. Common haematological abnormalities were thrombocytopenia and leucopoenia. Differences existed between the years in the percentage of patients with fever, elevated alanine aminotransferase (ALT), direct bilirubin, lactate dehydrogenase (LDH), fibrin degradation products (FDPs), and haemoglobin (Hb) levels. Differences were found in nationalities between the years, but patient nationality had no effect on disease incidence. Differences were noted in the percentages of patients' immunoglobulin M (IgM) and polymerase chain reaction (PCR) positive. There was a slight inverse correlation of IgM positive with patient age. PCR, fever, ALT, direct bilirubin, LDH, FDPs, Hb, blood transfusion, and platelet transfusion showed no correlation with age or nationality. In 2005, all the patients survived, but there were 4.55%, 25%, and 2.7% deaths during 2006-2008. Conclusions: Significant differences in the clinical presentation of dengue virus (DENV) infection, indicative of a variation in disease severity from dengue fever (DF) to dengue hemhorrhagic fever (DHF)/dengue shock syndrome (DSS), were noted over the years. Possible reasons are infection with different serotypes, concurrent/sequential infection of more than one serotype, and differences in host immune responses associated with host genetic variations.

scholarly journals Epidemio-Clinical Profile of Skin Conditions in Pediatric Dermatology Consultation of the University Hospital of Treichville

2018 ◽  
Vol 08 (04) ◽  
pp. 272-277
Author(s):  
Kouadio Célestin Ahogo ◽  
Kouamé Kanga ◽  
Kouassi Kouamé Alexandre ◽  
Allou Ange Sylvain ◽  
Enoh Jacob ◽  
...  
Keyword(s):  
Clinical Profile ◽  
University Hospital ◽  
Pediatric Dermatology ◽  
Skin Conditions ◽  
The University

scholarly journals Outcomes Bronchoscopic Evaluation in A University Hospital

2016 ◽  
Vol 55 (204) ◽  
pp. 51-54 ◽  
Author(s):  
Ram Hari Ghimire ◽  
Narendra Bhatta ◽  
Puru Koirala ◽  
Bides Bista ◽  
Deebya Raj Misra ◽  
...  
Keyword(s):  
Bronchoalveolar Lavage ◽  
Patient Care ◽  
Clinical Decision Making ◽  
Diagnostic Yield ◽  
Fiberoptic Bronchoscopy ◽  
Clinical Decision ◽  
Cross Sectional Study ◽  
Clinical Profile ◽  
University Hospital ◽  
Cross Sectional

Introduction: Study of clinical profile of the patients and diagnostic yield of the selected bronchoscopic procedures gives us important information in clinical decision making and better patient care. There are hardly very few studies regarding these entities. Therefore, we decided to study clinical characteristics and outcomes of the patients who underwent bronchoscopic evaluation in our setting. Methods: This was a cross-sectional study the consecutive patients who underwent bronchoscopy from 1st May 2013- 30th April 2015 in division of pulmonary, critical care and sleep medicine. The main procedure performed was bronchoalveolar lavage. Results: The mean age was 54.71 years with 76 (76%) males. Recurrent hemoptysis in 58 (58%) patients were the commonest indication. Total 95 (95%) patients have chest X-ray abnormalities. The commonest bronchoscopic finding was bronchiectasis 23 (23%) of patients followed by chronic bronchitis in 18 (18%) and endobronchial tuberculosis in 16 (16%). Total 10 (71%) of the 14 bronchoscopically suspected lung cancer patients have intraluminal lesions. Bronchoalveolar lavage culture for tuberculosis showed growth in 46 (46%), positive for malignancy in 7 (7%) positive Ziehl Neelson stain for tuberculosis in 6 (6%).Conclusions: Bronchoscopic evaluation of patients with pulmonary diseases gives us a lot of information that may help us in better patient care and bronchoalveolar lavage has high diagnostic yield in diagnosing pulmonary tuberculosis.Keywords: bronchoalveolar lavage;clinical profile;fiberoptic bronchoscopy. | PubMed

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