Correlation between the Level of Vitamin D and Bone Mass Index in Primary Osteoporotic Patients in Taif - KSA

2014 ◽  
Vol 57 ◽  
pp. 547-553
Author(s):  
Nagy A. Seleem ◽  
Azza A. Taha ◽  
Amal A. Soliman ◽  
Nehal M. Salama
Keyword(s):  
Vitamin D ◽  
Bone Mass ◽  
Bone Mass Index

Vitamin D receptor polymorphisms and bone mass indices in post menarcheal indian adolescent girls

2013 ◽  
Author(s):  
Sunil Kumar Kota ◽  
Lalit Kumar Meher ◽  
Sruti Jammula ◽  
Kirtikumar D Modi
Keyword(s):  
Vitamin D ◽  
Bone Mass ◽  
Adolescent Girls ◽  
Vitamin D Receptor

Diabetes and osteoporosis

2011 ◽  
Vol 152 (29) ◽  
pp. 1161-1166 ◽  
Author(s):  
Zsuzsanna Valkusz
Keyword(s):  
Vitamin D ◽  
Type 1 Diabetes ◽  
Bone Mass ◽  
Fragility Fractures ◽  
Vitamin D Supplementation ◽  
Bone Collagen ◽  
Skeletal Changes ◽  
Glucagon Like Peptide 1 ◽  
Bone Quantity

Over the last decades a considerable amount of data has accumulated to indicate that metabolic and endocrine alterations of diabetes affect bone quantity and quality. These skeletal changes may increase the risk of bone fracture. There is strong evidence that in type 1 diabetes the decreased bone mass, lack of insulin and insulin-like growth factor-1, dysregulation of adipokines, and increased levels of proinflammatory cytokines are in the background of fragility fractures. In type 2 diabetes hyperinsulinemia, insulin resistance and increased body weight may result in an increase of bone mass; however, accumulation of advanced glycation end products within the bone collagen driven by glucotoxicity may increase the cortical porosity. There is a higher incidence of falls resulting from diabetes-related co-morbidities such as diabetic retinopathy, peripheral neuropathy, hypoglycemic episodes and sometimes from the medications. Vitamin D deficiency has special impact on glucose metabolism and the prevalence of diabetes. Vitamin D supplementation in childhood can decrease incidence of type 1 diabetes by 80%. The effect of thiazolidinediones, glucagon-like peptide-1 agonists and metformin, agents for treatment of diabetes open a new connection between bone, carbohydrate and fat metabolism. Orv. Hetil., 2011, 152, 1161–1166.

Associations of Dietary Calcium, Vitamin D, Milk Intakes, and 25-Hydroxyvitamin D With Bone Mass in Spanish Adolescents: The HELENA Study

2013 ◽  
Vol 16 (1) ◽  
pp. 110-117 ◽  
Author(s):  
Theodora Mouratidou ◽  
German Vicente-Rodriguez ◽  
Luis Gracia-Marco ◽  
Inge Huybrechts ◽  
Isabelle Sioen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Mass ◽  
Dietary Calcium ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Helena Study

Is BsmI vitamin-D receptor gene polymorphism associated with combined bone mass in spine and proximal femur in icelandic women?

1996 ◽  
Vol 6 (S1) ◽  
pp. 157-157
Author(s):  
G. Sigurdsson ◽  
D. N. Magnúsdóttir ◽  
J. O. Kristinsson ◽  
K. Kristjánsson ◽  
I. Olaisson
Keyword(s):  
Vitamin D ◽  
Gene Polymorphism ◽  
Bone Mass ◽  
Vitamin D Receptor ◽  
Proximal Femur ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Receptor Gene Polymorphism

scholarly journals Evaluation of bone mineral density (BMD) and indicators of bone turnover in patients with hemophilia

2018 ◽  
Vol 18 (2) ◽  
pp. 206-210 ◽  
Author(s):  
Mehmet Dagli ◽  
Ali Kutlucan ◽  
Sedat Abusoglu ◽  
Abdulkadir Basturk ◽  
Mehmet Sozen ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Formation ◽  
Bone Mass ◽  
Bone Mineral ◽  
Type I ◽  
Healthy Controls ◽  
Mineral Density ◽  
Lymphocyte Ratio ◽  
Significant Difference

A decrease in bone mass is observed in hemophilic patients. The aim of this study was to evaluate bone mineral density (BMD), parathyroid hormone (PTH), 25-hydroxy vitamin D (vitamin D), and a bone formation and resorption marker, procollagen type I N-terminal propeptide (PINP) and urinary N-terminal telopeptide (uNTX) respectively, in hemophilic patients and healthy controls. Laboratory parameters related to the pathogenesis of bone loss such as neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) were also evaluated. Thirty-five men over 18 years of age, with severe hemophilia (A and B) and receiving secondary prophylaxis, were included in the study. The same number of age-, sex-, and ethnicity-matched healthy controls were evaluated. Anthropometric, biochemical, and hormonal parameters were determined in both groups. No significant difference in anthropometric parameters was found between the two groups. The BMD was low in 34% of hemophilic patients. Vitamin D, calcium, and free testosterone levels were significantly lower (p < 0.001, p = 0.011, p < 0.001, respectively), while PTH, PINP, and activated partial thromboplastin time (aPTT) levels were significantly higher (p < 0.014, p = 0.043, p < 0.001, respectively), in hemophilic patients compared to controls. There was no significant difference between the two groups in NLR, PLR, phosphorus, thyroid-stimulating hormone, and uNTX level. The reduction of bone mass in hemophilic patients may be evaluated using the markers of bone formation and resorption, enabling early detection and timely treatment.

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