scholarly journals Clinical Progress Note: High Flow Nasal Cannula Therapy for Bronchiolitis Outside the ICU in Infants

2019 ◽  
Vol 15 (01) ◽  
pp. 49-50 ◽  
Author(s):  
Laura Piper ◽  
Erika L Stalets ◽  
Angela M Statile
Keyword(s):  
The United States ◽  
Supplemental Oxygen ◽  
High Flow ◽  
Nasal Cannula ◽  
High Flow Nasal Cannula ◽  
Flow Rates ◽  
Common Indication ◽  
Heated Air ◽  
Inpatient Settings ◽  
Infant Hospitalization

Viral bronchiolitis is the most common indication for infant hospitalization in the United States.1 The treatment mainstay remains supportive care, including supplemental oxygen when indicated.1 High flow nasal cannula (HFNC) therapy delivers humidified, heated air blended with oxygen, allowing much higher flow rates than standard nasal cannula therapy and is being used more frequently in inpatient settings.

scholarly journals Diaphragm electromyography results at different high flow nasal cannula flow rates

2019 ◽  
Vol 178 (8) ◽  
pp. 1237-1242 ◽  
Author(s):  
Eleanor Jeffreys ◽  
Katie A Hunt ◽  
Theodore Dassios ◽  
Anne Greenough
Keyword(s):  
High Flow ◽  
Nasal Cannula ◽  
High Flow Nasal Cannula ◽  
Flow Rates

scholarly journals EFFICACY OF EARLY PRONE POSITIONING IN PATIENTS WITH COVID-19 PNEUMONIA REQUIRING SUPPLEMENTAL OXYGEN, HIGH FLOW NASAL CANNULA, OR NONINVASIVE VENTILATION

CHEST Journal ◽  
2020 ◽  
Vol 158 (4) ◽  
pp. A2281-A2282
Author(s):  
Jacob Bell ◽  
Patricia Dharapak ◽  
Paru Patrawalla ◽  
Dewan Giri ◽  
Justin Gasper ◽  
...  
Keyword(s):  
Noninvasive Ventilation ◽  
Supplemental Oxygen ◽  
High Flow ◽  
Nasal Cannula ◽  
Prone Positioning ◽  
High Flow Nasal Cannula

scholarly journals High-flow nasal cannula versus standard oxygen therapy assisting sedation during endoscopic retrograde cholangiopancreatography in high risk cases (OTHER): study protocol of a randomised multicentric trial

2020 ◽  
Author(s):  
Venkatesan Thiruvenkatarajan ◽  
Ashok Dharmalingam ◽  
Gilberto Arenas ◽  
Medhat Wahba ◽  
Reinhard Steiner ◽  
...  
Keyword(s):  
High Risk ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Perioperative Complications ◽  
Supplemental Oxygen ◽  
High Flow ◽  
Nasal Cannula ◽  
Low Flow ◽  
High Flow Nasal Cannula ◽  
Endoscopic Retrograde ◽  
Study Results

Abstract Background Endoscopic retrograde cholangiopancreatography (ERCP) is an increasingly common intervention in the treatment of pancreatico-biliary disorders. Patients are often elderly with complex co-morbidities. While monitored anaesthesia care with sedation is commonly used for most cases, few would require general anaesthesia with an endotracheal tube. Both low flow and high flow nasal cannulas (HFNC) are established ways of delivering supplemental oxygen, but it is unclear whether one technique is better than the other. HFNC seems a promising tool for advanced procedures but evidence to support its application in high-risk ERCP cases is limited. The rate of oxygen desaturation during endoscopy has been reported to be as high as 11-50%, and the method of oxygen delivery for ERCP merits further study. Methods/design This is a prospective, randomised, multi-centre trial comparing the efficacy of oxygen supplementation through high flow nasal cannula versus low flow nasal cannula during ERCP, in a cohort of patients at risk of adverse respiratory events. A total of 132 patients will be recruited across three sites and randomly assigned to either the low flow or the HFNC group. The primary outcome is the proportion of patients experiencing hypoxia, defined by any event of SpO2 <90%. The secondary outcomes include parameters centred on oxygenation, requirement of airway manoeuvres, successful completion of procedure, perioperative complications, patient satisfaction, and cost analysis of the consumables. An intention-to-treat principle will be applied while analysing. Discussion The demand for ERCPs is likely to increase in the future with the aging population. Our study results may lead to improved outcomes and reduce airway related complications in patients undergoing ERCPs. The results will be presented at national and international meetings and published in per-reviewed journals.

scholarly journals High-flow nasal cannula versus standard oxygen therapy assisting sedation during endoscopic retrograde cholangiopancreatography in high risk cases (OTHER): study protocol of a randomised multicentric trial

2020 ◽  
Author(s):  
Venkatesan Thiruvenkatarajan ◽  
Ashok Dharmalingam ◽  
Gilberto Arenas ◽  
Medhat Wahba ◽  
Reinhard Steiner ◽  
...  
Keyword(s):  
High Risk ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Perioperative Complications ◽  
Supplemental Oxygen ◽  
High Flow ◽  
Nasal Cannula ◽  
Low Flow ◽  
High Flow Nasal Cannula ◽  
Endoscopic Retrograde ◽  
Study Results

Abstract Background Endoscopic retrograde cholangiopancreatography (ERCP) is an increasingly common intervention in the treatment of pancreatico-biliary disorders. Patients are often elderly with complex co-morbidities. While monitored anaesthesia care with sedation is commonly used for most cases, few would require general anaesthesia with an endotracheal tube. Both low flow and high flow nasal cannulas (HFNC) are established ways of delivering supplemental oxygen, but it is unclear whether one technique is better than the other. HFNC seems a promising tool for advanced procedures but evidence to support its application in high-risk ERCP cases is limited. The rate of oxygen desaturation during endoscopy has been reported to be as high as 11-50%, and the method of oxygen delivery for ERCP merits further study.Methods/design This is a prospective, randomised, multi-centre trial comparing the efficacy of oxygen supplementation through high flow nasal cannula versus low flow nasal cannula during ERCP, in a cohort of patients at risk of adverse respiratory events. A total of 132 patients will be recruited across three sites and randomly assigned to either the low flow or the HFNC group. The primary outcome is the proportion of patients experiencing hypoxia, defined by any event of SpO2 <90%. The secondary outcomes include parameters centred on oxygenation, requirement of airway manoeuvres, successful completion of procedure, perioperative complications, patient satisfaction, and cost analysis of the consumables. An intention-to-treat principle will be applied while analysing.Discussion The demand for ERCPs is likely to increase in the future with the aging population. Our study results may lead to improved outcomes and reduce airway related complications in patients undergoing ERCPs. The results will be presented at national and international meetings and published in per-reviewed journals.Trial registration: www.ANZCTR.org.au CTRN12619000397112, Registered on on March 12, 2019.

scholarly journals The application of an oxygen mask, without supplemental oxygen, improved oxygenation in patients with severe COVID-19 already treated with high-flow nasal cannula

Critical Care ◽  
2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Besarta Dogani ◽  
Fredrik Månsson ◽  
Fredrik Resman ◽  
Hannes Hartman ◽  
Johan Tham ◽  
...  
Keyword(s):  
Supplemental Oxygen ◽  
High Flow ◽  
Nasal Cannula ◽  
High Flow Nasal Cannula ◽  
Oxygen Mask

scholarly journals Pneumomediastinum in a patient with COVID-19 due to diffuse alveolar damage

2021 ◽  
Vol 14 (5) ◽  
pp. e242527
Author(s):  
Frank Heijboer ◽  
Laurien Oswald ◽  
Sander Cretier ◽  
Gert-Jan Braunstahl
Keyword(s):  
Diffuse Alveolar Damage ◽  
Supplemental Oxygen ◽  
High Flow ◽  
Nasal Cannula ◽  
Positive End Expiratory Pressure ◽  
High Flow Nasal Cannula ◽  
Progressive Dyspnoea

A 74-year-old man with COVID-19 was admitted and experienced progressive dyspnoea while receiving supplemental oxygen via high-flow nasal cannula (HFNC). A CT of the thorax showed a pneumomediastinum. The HFNC was temporally interrupted, since it was uncertain whether the positive end-expiratory pressure of the HFNC could be the cause of the pneumomediastinum. After restart of the HFNC, there was no increase of symptoms. We suggest that the pneumomediastinum was the result of COVID-19-related alveolar damage, and not due to the use of HFNC. This observation is relevant since HFNC is often used in the treatment of severe COVID-19 pneumonia.

Optimum support by high-flow nasal cannula in acute hypoxemic respiratory failure: effects of increasing flow rates

2017 ◽  
Vol 43 (10) ◽  
pp. 1453-1463 ◽  
Author(s):  
Tommaso Mauri ◽  
Laura Alban ◽  
Cecilia Turrini ◽  
Barbara Cambiaghi ◽  
Eleonora Carlesso ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
High Flow ◽  
Nasal Cannula ◽  
High Flow Nasal Cannula ◽  
Hypoxemic Respiratory Failure ◽  
Acute Hypoxemic Respiratory Failure ◽  
Flow Rates

Nasal Cannula, CPAP, and High-Flow Nasal Cannula: Effect of Flow on Temperature, Humidity, Pressure, and Resistance

2011 ◽  
Vol 45 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Gordon Y. Chang ◽  
Cynthia A. Cox ◽  
Thomas H. Shaffer
Keyword(s):  
Positive Airway Pressure ◽  
Work Of Breathing ◽  
Supplemental Oxygen ◽  
High Flow ◽  
Nasal Cannula ◽  
In Vivo Studies ◽  
High Flow Nasal Cannula ◽  
Potential Benefits ◽  
Flow Pressure

Abstract Background: Delivery of warm, humidified, supplemental oxygen via high-flow nasal cannula has several potential benefits; however, the high-flow range may not maintain humidification and temperature and in some cases may cause excessive expiratory pressure loading. Objective: To compare the effect of flow on temperature, humidity, pressure, and resistance in nasal cannula (NC), continuous positive airway pressure (CPAP), and high-flow nasal cannula (HFNC) in a clinical setting. Methods: The three delivery systems were tested in the nursery using each instrument's recommended specifications and flow ranges (0–3 L/min and 0–8 L/min). Flow, pressure, temperature, and humidity were measured, and resistance was calculated. Results: For all devices at 0–3 L/min, there was a difference (p&lt;0.01) in temperature (NC 35.9°C &gt; CPAP 34.5°C &gt; HFNC 34.0°C), humidity (HFNC 82% &gt; CPAP 77% &gt; NC 57%), pressure (HFNC 22 cmH2O &gt; NC 4 cmH2O &gt; CPAP 3 cmH2O), and resistance (HFNC 636 cmH2O/L/sec &gt; NC 270 cmH2O/L/sec &gt; CPAP 93 cmH2O/L/sec) as a function of flow. For HFNC and CPAP at 0–8 L/min, there was a difference (p&lt;0.01) in temperature (CPAP 34.5°C &gt; HFNC 34.0°C) in humidity (HFNC 83 % &gt; CPAP 76 %), pressure (HFNC 56 cmH2O &gt; CPAP 14 cmH2O) and resistance (HFNC 783 cmH2O/L/sec &gt; CPAP 280 cmH2O/L/sec) as a function of flow. Conclusions: Gas delivered by HFNC was more humid than NC and CPAP. However, the higher pressure and resistance delivered by the HFNC system may have clinical relevance, such as increased work of breathing, and warrants further in vivo studies.

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