Impact of trimodality treatment on patient quality of life and arm function for superior sulcus tumors

2016 ◽  
Vol 14 (3) ◽  
pp. 107-111
Author(s):  
Cornelis Vos ◽  
Ramon Gorter ◽  
Koen Hartemink ◽  
J Wolter Oosterhuis
Keyword(s):  
Quality Of Life ◽  
Superior Sulcus Tumors ◽  
Arm Function ◽  
Superior Sulcus ◽  
Trimodality Treatment

scholarly journals Evaluation of arm function and quality of life after trimodality treatment for superior sulcus tumours

2012 ◽  
Vol 16 (1) ◽  
pp. 44-48 ◽  
Author(s):  
R. R. Gorter ◽  
C. G. Vos ◽  
J. Halmans ◽  
K. J. Hartemink ◽  
M. A. Paul ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Arm Function ◽  
Superior Sulcus ◽  
Trimodality Treatment

scholarly journals THORACIC SURGERY Early results of a trimodality treatment for superior sulcus tumors

2014 ◽  
Vol 3 ◽  
pp. 268-272
Author(s):  
Mariusz Łapiński ◽  
Rafał Dziadziuszko ◽  
Wioletta Sawicka ◽  
Witold Rzyman
Keyword(s):  
Thoracic Surgery ◽  
Early Results ◽  
Superior Sulcus Tumors ◽  
Superior Sulcus ◽  
Trimodality Treatment

Trimodality treatment in patients with superior sulcus tumors: Hopes and realities

2011 ◽  
Vol 97 (4) ◽  
pp. 459-465
Author(s):  
Zafer Kocak ◽  
Mert Saynak ◽  
Kazim Uygun ◽  
Yener Yoruk ◽  
Alaattin Ozen ◽  
...  
Keyword(s):  
Superior Sulcus Tumors ◽  
Superior Sulcus ◽  
Trimodality Treatment

Sustained-released fampridine in multiple sclerosis: effects on gait parameters, arm function, fatigue, and quality of life

2015 ◽  
Vol 262 (8) ◽  
pp. 1936-1945 ◽  
Author(s):  
Etienne Allart ◽  
Anne Benoit ◽  
Anne Blanchard-Dauphin ◽  
Vincent Tiffreau ◽  
André Thevenon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Gait Parameters ◽  
Arm Function

scholarly journals Impact of Physiotherapy on Quality of Life and Arm Function after Breast Cancer Surgery in Women of Different Age

2020 ◽  
Vol 2 (9) ◽  
Author(s):  
Aušra Tvarijonavičienė
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Range Of Motion ◽  
General Health ◽  
Cancer Surgery ◽  
Breast Cancer Surgery ◽  
Shoulder Range Of Motion ◽  
Arm Function ◽  
Shoulder Range

Breast cancer is the most common oncological disease among women. After breast cancer surgery women face various physical and psychosocial problems. They often suffer from arm lymphedema, poor posture, and pain. Side effects of breast cancer surgery can greatly affect general physical health and quality of life. To manage the problems it is necessary to apply rehabilitation. The most important part of rehabilitation is physiotherapy with the main aim of helping patients to recover and to achieve their maximum functional level (Hsieh et al., 2008). The aim of this study was to determine the impact of physiotherapy on differently aged women’s arm function after breast cancer surgery. The sample size of the survey was 40 women who were referred for post operative outpatient rehabilitation. The participants were divided into two age groups: I group – women aged 35–49 years (n = 20, average age 42 ± 4.30 yrs.); II group – women aged 50–64 years (n = 20, average age 56 ± 5.39 yrs.). Shoulder range of motion, arm circumference and pain were measured before and after 14 physiotherapy procedures, their general health state and quality of life were assessed as well. Shoulder range of motion increased, arm swelling and pain on the operated side decreased significantly in women of different age. General health status and quality of life after physiotherapy improved significantly both in younger and older women, but there were no significant differences between groups. After breast cancer surgery more than half of the women had psychological problems and were worried about their health in future, and less than half experienced body image problems and faced various social problems. Physical therapy was equally effective for both younger and older women.Keywords: physiotherapy, breast cancer, lymphedema, quality of life.

scholarly journals Standardized algorithm for muscle selection and dosing of botulinum toxin for Parkinson tremor using kinematic analysis

2020 ◽  
Vol 13 ◽  
pp. 175628642095408
Author(s):  
Olivia Samotus ◽  
Jack Lee ◽  
Mandar Jog
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Botulinum Toxin ◽  
Grip Strength ◽  
Treatment Algorithm ◽  
Standardized Treatment ◽  
Arm Function ◽  
Tremor Analysis

Background: Inadequate efficacy and significant side effect profile makes pharmacological treatment of Parkinson’s disease (PD) tremor challenging. Personalized dosing of botulinum toxin type A (BoNT-A) using tremor analysis has shown efficacy and safety for treating upper limb tremor. This study incorporated a novel, standardized treatment algorithm for determining injection pattern and BoNT-A dosing, customizable by the physician, in PD patients with disabling tremor in one or both arms. Methods: This open-label study included 47 PD participants (25 “De-novo” and 22 “L-dopa”) who received 4 serial BoNT-A treatments with follow-ups at 6 weeks post-treatment over 42 weeks. The treatment algorithm utilized kinematic tremor analysis of each participant’s whole arm tremor and determined the physician’s injection pattern of BoNT-A. Endpoints included changes in angular tremor amplitude, Fahn-Tolosa-Marin (FTM C) tremor scale, Movement Disorder Society-Unified Parkinson’s disease rating scale (MDS-UPDRS) tremor-related score, tremor-related quality of life questionnaire, Likert ratings of perceived weakness, and maximal grip strength. Results: BoNT-A significantly ( p < 0.05) improved tremor amplitude (41.6%), quality of life (23.0%), UPDRS tremor score (29.6%), and arm function (FTM C; 24.6%) for both treatment cohorts from weeks 6 to 42. Maximum grip strength was reduced between 7.4% and 23.0% at follow-up visits and did not impact activities of daily living. Efficacy was obtained with first injection and remained without adjustment over two serial injection in 45% of participants. Conclusions: This is the first study to use a fully standardized treatment algorithm for personalization of BoNT-A injection patterns for disabling PD tremor over serial treatments. A sustained alleviation of tremor severity and improved arm function and quality of life fulfills an important unmet need for the treatment of PD tremor. This study demonstrated that BoNT-A can be administered as a monotherapy in tremor-dominant PD or as an add-on therapy for refractory PD tremor.

scholarly journals Az osztott dózisú trimodális kezelés első hazai alkalmazása nagy kockázatú húgyhólyagdaganat esetében

2021 ◽  
Vol 162 (50) ◽  
pp. 2017-2022
Keyword(s):  
Quality Of Life ◽  
Radical Cystectomy ◽  
Histopathological Examination ◽  
Tumor Resection ◽  
High Grade ◽  
Trimodality Therapy ◽  
Bladder Biopsy ◽  
Viable Tumor ◽  
Trimodality Treatment

Összefoglaló. Az izominvazív vagy nagyon nagy kockázatú, felületes hólyagdaganatok kezelésének arany standardja a radikális húgyhólyag-eltávolítás (cystectomia). Válogatott betegek esetében hasonló hatékonyságú kezelés lehet az osztott dózisú (split-course) trimodális terápia, az endoszkópos tumorreszekció és a kemoirradiáció megszakított ciklusokkal történő alkalmazása. A split-course trimodális terápia a radikális cystectomiához hasonló eredményességű, a későbbi életminőség szempontjából pedig ígéretes kezelési lehetőség lehet megfelelően kiválasztott betegek esetében. Hazánkban első alkalommal végzett kezelést ismertetünk a téma szakirodalmi áttekintése mellett. A húgyhólyagtumor transurethralis reszekciója, maximális eradikációja után kemoirradiáció kezdődik, melyet 45 Gy sugárdózis elérésekor ismételt szövettani mintavétel szakít meg. Negatív szövettani eredmény esetén a megkezdett terápia a teljes dózis eléréséig folytatandó. Amennyiben a reszekció során élő tumor észlelhető, a radikális műtét elvégzése javasolt. A korábban transurethralis daganatreszekción négyszer átesett 54 éves beteg lokális immunterápia utáni recidívájának szövettana pT1, ’high grade’ urothelialis carcinoma volt. A jól informált, kiváló fizikális statusú beteg kérését figyelembe véve split-course trimodális kezelést végeztünk. Negatív ’staging’ vizsgálatok után maximális endoszkópos reszekció, majd kemoirradiáció következett. A 45 Gy besugárzás elérésekor elvégzett ismételt mintavétel azonnal feldolgozott szövettana negatív eredményt mutatott, így késedelem nélkül folytatódott a kemoirradiációs kezelés. Az eddigi kontrollvizsgálatok alapján a beteg komplett remisszióban van. A split-course trimodális terápia a radikális hólyageltávolítás megfelelő alternatívája jól informált, gondosan megválogatott betegek esetében. A szervmegtartó eljárás jobb életminőséget eredményezhet, ugyanakkor a beteget feltétlenül tájékoztatni kell, hogy sikertelenség esetén a radikális műtét is szükségessé válhat. A kezelés sikeres menedzselése csak a társszakmák szoros, jól tervezett együttműködésével lehetséges. Orv Hetil. 2021; 162(50): 2017–2022. Summary. While radical cystectomy remains the gold standard to treat muscle-invasive or very high risk superficial bladder cancer, well selected patients can be offered split-course multimodal treatment as a similarly effective alternative, combining endoscopic tumor resection and split-course chemoradiotherapy. In highly selected patients, split-course trimodality therapy can lead to survival rates comparable to radical cystectomy with better quality of life outcomes. We present our experience with split-course trimodality treatment used for the very first time in Hungary. Maximal transurethral resection of bladder neoplasm is followed by chemoradiotherapy with repeated bladder biopsy after 45 Gy of irradiation. With negative biopsy results, chemoirradiation should be continued until full dose given. Salvage cystectomy is recommended if viable tumor is detected. Our patient (54), who previously underwent four transurethral bladder tumor resections and local immunotherapy, presented with pT1, high grade urothelial carcinoma recurrence. The well-informed, high performance status patient opted for split-course trimodality treatment. After negative staging scan results, the patient underwent complete endoscopic tumor eradication, followed by chemoradiotherapy. After 45 Gy of irradiation, repeated bladder biopsy was performed. The immediate histopathological examination found no viable tumor, therefore chemoradiotherapy was completed. Follow-up examinations suggest our patient in complete remission. Split-course trimodality treatment can be offered to well-informed and selected patients as a reasonable alternative to radical cystectomy. Though the bladder-sparing approach results in better quality of life, patients must know that in the case of treatment failure, radical cystectomy will likely be offered. Excellent multidisciplinary cooperation is a key to conduct this treatment alternative successfully. Orv Hetil. 2021; 162(50): 2017–2022.

Pain in Head and Neck Cancer Survivors: Prevalence, Predictors, and Quality-of-Life Impact

2018 ◽  
Vol 159 (5) ◽  
pp. 853-858 ◽  
Author(s):  
John D. Cramer ◽  
Jonas T. Johnson ◽  
Marci L. Nilsen
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Multivariable Analysis ◽  
Comprehensive Management ◽  
Patients With Cancer ◽  
Life Impact ◽  
Trimodality Treatment

Objectives Pain is common among patients with cancer, stemming from both malignancy and side effects of treatment. The extent to which pain persists after treatment has received little attention. We examined the prevalence, predictors, and impact on quality of life (QOL) caused by pain among survivors of head and neck cancer. Study Design Cohort study. Setting Tertiary head and neck cancer survivorship clinic. Subjects and Methods We identified survivors of head and neck cancer ≥1 year after diagnosis and examined the prevalence and risk factors for development of pain. Pain and QOL were assessed with multiple QOL instruments. Ordinal regression modeling examined predictors of pain in survivors. Results We identified 175 patients at a median of 6.6 years after diagnosis. Among survivors, 45.1% reported pain, and 11.5% reported severe pain. Among patients with current pain, 46% reported low overall QOL versus only 12% of those without pain ( P < .001). On multivariable analysis after adjustment for age, sex, and stage of disease, pain was associated with trimodality treatment (odds ratio [OR], 3.55; 95% CI, 1.06-12.77). Multivariable analysis of QOL issues revealed that pain was associated with major depression (OR, 3.91; 95% CI, 1.68-9.11), anxiety (OR, 4.22; 95% CI, 2.28-7.81), poor recreation (OR, 3.31; 95% CI, 1.70-6.48), and low overall QOL (OR, 2.20; 95% CI, 1.12-4.34). Conclusions Years after head and neck cancer treatment, pain remains a significant problem and is associated with worse QOL. Future efforts should focus on preventing pain from treatment and comprehensive management.

Sign in / Sign up

Export Citation Format

Share Document