scholarly journals Pediatric-Onset Refractory Lupus Erythematosus Panniculitis Treated With Rituximab

2021 ◽  
Vol 108 (2) ◽  
Author(s):  
Divya Angra
Keyword(s):  
Lupus Erythematosus ◽  
Lupus Erythematosus Panniculitis ◽  
Pediatric Onset

Excellent Response to Hydroxychloroquine in a Young Man with Lupus Erythematosus Panniculitis

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Parigini Aníbal María ◽  
Diego María Clara de ◽  
Beguerie Julieta Ruiz ◽  
Paredes Victoria Duran ◽  
Anaya Javier
Keyword(s):  
Lupus Erythematosus ◽  
Excellent Response ◽  
Lupus Erythematosus Panniculitis

scholarly journals Autologous fat grafting for treating lipoatrophy secondary to lupus erythematosus panniculitis

2016 ◽  
Vol 49 (1) ◽  
pp. 27-30
Author(s):  
Hsiao-Peng Huang ◽  
Yung-Chia Huang ◽  
Yuan-Sheng Tzeng ◽  
Chih-Hsin Wang ◽  
Tim-Mo Chen ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Fat Grafting ◽  
Autologous Fat Grafting ◽  
Autologous Fat ◽  
Lupus Erythematosus Panniculitis

scholarly journals Complement deficiency in pediatric-onset systemic lupus erythematosus

2018 ◽  
Vol 10 (02) ◽  
pp. 232-236 ◽  
Author(s):  
Parisa Afzali ◽  
Anna Isaeian ◽  
Peyman Sadeghi ◽  
Bobak Moazzami ◽  
Nima Parvaneh ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Musculoskeletal Symptoms ◽  
Complement C3 ◽  
Complement Deficiency ◽  
Control Group ◽  
Systemic Lupus ◽  
Cutaneous Manifestations ◽  
Pediatric Onset ◽  
Onset Systemic Lupus Erythematosus

Abstract BACKGROUND: Pediatric-onset systemic lupus erythematosus (pSLE) accounts for about 10%-20% of all patients with SLE. Deficiencies in early complement components of the classical pathway are the strong genetic risk factor for the development of SLE. In this study, clinical and laboratory manifestations of both complement-deficient and normal complement pSLE patients were compared. MATERIALS AND METHODS: To investigate clinical and immunological manifestations of pSLE in Iran, 36 consecutive pSLE patients (onset before 18 years) who were followed up over a period of 2 years, were studied. Complement C1q and C2 levels were measured using radial immunodifusion assay and complement C3 and C4 levels were measured using nephelometry. Medical records were retrospectively evaluated from patient database of Children Medical Center Hospital. Data were assessed through descriptive analysis (confidence interval = 95%), paired t-test, and Pearson correlation test. RESULTS: Twenty-one patients (58%) had at least one component of complement deficiency. Ten patients (27%) had low C1q level, 11 patients (30.5%) had low C2, nine patients (25%) had low C3, and four patients (11%) had low C4 level. Serum level of complement in pSLE was significantly lower than the control group, except C4 (P = 0.005). The low C1q patients had an earlier age of onset of disease (P < 0.0001). The cutaneous manifestations were more frequent and much more severe in pSLE with low complement (100% vs. 73%). The frequency of renal and musculoskeletal symptoms was equal, but renal morbidity was more common in pSLE with low complement. Positivity for anti-ds-DNA was less common in pSLE with low complement (71% vs. 86%). CONCLUSION: In pSLE patients with early disease onset and more aggressive SLE manifestations and negative anti-ds-DNA test, complement deficiency should be considered.

scholarly journals Treatment of Childhood-Onset Lupus Erythematosus Panniculitis With Rituximab

2020 ◽  
Vol 156 (5) ◽  
pp. 566
Author(s):  
Colleen K. Correll ◽  
Daniel D. Miller ◽  
Sheilagh M. Maguiness
Keyword(s):  
Lupus Erythematosus ◽  
Childhood Onset ◽  
Lupus Erythematosus Panniculitis

Anti-tumour necrosis factor α-induced lupus erythematosus panniculitis

2017 ◽  
Vol 31 (7) ◽  
pp. e318-e319 ◽  
Author(s):  
A.-L. Durand ◽  
J.-F. Goussot ◽  
D. Thiolat ◽  
A. Taieb ◽  
J. Marie ◽  
...  
Keyword(s):  
Tumour Necrosis Factor ◽  
Lupus Erythematosus ◽  
Tumour Necrosis ◽  
Tumour Necrosis Factor Α ◽  
Factor Α ◽  
Necrosis Factor ◽  
Lupus Erythematosus Panniculitis
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