The Effect of Transcranial Direct Current Stimulation on Cortical Excitability and Motor Function in a Stroke Patient -A case report-

2011 ◽  
Vol 4 (1) ◽  
pp. 57
Author(s):  
Lee-suk Kim ◽  
Dae-Yul Kim
Keyword(s):  
Case Report ◽  
Motor Function ◽  
Stroke Patient ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Cortical Excitability ◽  
Direct Current Stimulation

scholarly journals Interhemispheric Modulation Induced by Cortical Stimulation and Motor Training

2010 ◽  
Vol 90 (3) ◽  
pp. 398-410 ◽  
Author(s):  
Julie A. Williams ◽  
Alvaro Pascual-Leone ◽  
Felipe Fregni
Keyword(s):  
Motor Function ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Motor Performance ◽  
Cortical Excitability ◽  
Motor Training ◽  
Interhemispheric Inhibition ◽  
Direct Current Stimulation ◽  
Nondominant Hand ◽  
Contralateral Hand

Background Interhemispheric inhibition might be a beneficial cortico-cortical interaction, but also might be maladaptive in people with neurological disorders. One recently revisited technique that has been shown to be effective in improving motor function in people with stroke using interhemispheric modulation is transcranial direct current stimulation (tDCS). Objective The aim of this study was to investigate the effects of tDCS combined with unilateral motor training with contralateral hand restraint on interhemispheric inhibition between the dominant and nondominant hemispheres of the brain and on motor performance in participants who were healthy. Design This was a double-blind, prospective, single-center study with participants who were healthy. Methods Twenty participants who were healthy were randomly assigned to receive either active or sham tDCS of the primary motor cortex (M1) bilaterally combined with unilateral motor training and contralateral hand restraint. A blinded rater assessed motor function and cortical excitability, including assessment of transcallosal inhibition (TCI). Results There was a larger increase in motor performance in the nondominant hand for the active tDCS group compared with the sham tDCS group. In addition, a decrease in cortical excitability in the dominant hemisphere and a decrease in TCI from the dominant to nondominant hemisphere were observed for the active tDCS group only. The TCI decrease in the active tDCS group was correlated with motor performance improvement for the nondominant hand. Limitations Limitations of this study included missing the effect of intracortical inhibition due to a floor effect, not using the optimal tDCS montage, and not being able to assess the effects of other variables such as gender due to the small sample size. Conclusions The results indicate that tDCS enhances the effects of unilateral motor training and contralateral hand restraint on motor function, and this benefit is associated with a different mechanism of action characterized by bihemispheric modulation in which TCI from the dominant to the nondominant hemisphere is decreased. Transcranial direct current stimulation might be a useful tool to enhance the motor effects of constraint-induced movement therapy.

scholarly journals Effect of Short Period Simultaneous Stimulation of Transcranial Direct Current Stimulation (tDCS) on Occupational Therapy to Motor Function of Upper Extremity in Stroke Subject

2020 ◽  
Vol 2 (2) ◽  
pp. 66
Author(s):  
Adrian Utomo ◽  
I Lukitra Wardhani ◽  
I Putu Alit Pawana
Keyword(s):  
Occupational Therapy ◽  
Ischaemic Stroke ◽  
Upper Extremity ◽  
Motor Function ◽  
Stroke Patient ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Intervention Group ◽  
Control Group ◽  
Direct Current Stimulation

ABSTRACTObjective: Stroke could cause upper extremity motor function disturbances that may affect to quality of life. The affected brain has an ability to get recovery by neuroplasticity process. Transcranial direct current stimulation (tDCS) is a non-invasive modality that could induce brain neuroplasticity Goal: To determine the effect of tDCS stimulation on recovery of upper extremity motor function in subacute ischaemic stroke patient. Methods: 22 stroke patients included in inclusion criteria, divided into 2 groups, control group and intervention group. Control group had occupational therapy for 5 days consecutively and intervention group had occupational therapy and tDCS stimulation simultaneously for 5 days consecutively. Upper extremity motor function was evaluated with Fugl-Meyer Assessment (FMA) before and after the treatment. Results: Significant improvement of FMA score on control group (p=0,018) and intervention group (p=0,000). Comparison of the result after the treatment revealed that the intervention group showed more significant improvement in FMA score than the control group (p=0,000). Conclusion: Application of tDCS stimulation on occupational therapy simultaneously showed improvement of upper extremity motor function in subacute ischaemic stroke patient better than only occupational therapy. Key Words: Transcranial direct current stimulation, occupational therapy, Fugl-Meyer Assessment, upper extremity motor function, subacute ischemic stroke.

scholarly journals The effects of transcranial direct current stimulation on gait in patients with Parkinson’s disease: a systematic review

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Fateme Pol ◽  
Mohammad Ali Salehinejad ◽  
Hamzeh Baharlouei ◽  
Michael A. Nitsche
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Randomized Clinical Trials ◽  
Cortical Excitability ◽  
Experimental Studies ◽  
Gait Rehabilitation ◽  
Direct Current Stimulation

Abstract Background Gait problems are an important symptom in Parkinson’s disease (PD), a progressive neurodegenerative disease. Transcranial direct current stimulation (tDCS) is a neuromodulatory intervention that can modulate cortical excitability of the gait-related regions. Despite an increasing number of gait-related tDCS studies in PD, the efficacy of this technique for improving gait has not been systematically investigated yet. Here, we aimed to systematically explore the effects of tDCS on gait in PD, based on available experimental studies. Methods Using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) approach, PubMed, Web of Science, Scopus, and PEDro databases were searched for randomized clinical trials assessing the effect of tDCS on gait in patients with PD. Results Eighteen studies were included in this systematic review. Overall, tDCS targeting the motor cortex and supplementary motor area bilaterally seems to be promising for gait rehabilitation in PD. Studies of tDCS targeting the dorosolateral prefrontal cortex or cerebellum showed more heterogeneous results. More studies are needed to systematically compare the efficacy of different tDCS protocols, including protocols applying tDCS alone and/or in combination with conventional gait rehabilitation treatment in PD. Conclusions tDCS is a promising intervention approach to improving gait in PD. Anodal tDCS over the motor areas has shown a positive effect on gait, but stimulation of other areas is less promising. However, the heterogeneities of methods and results have made it difficult to draw firm conclusions. Therefore, systematic explorations of tDCS protocols are required to optimize the efficacy.

scholarly journals Gender-specific modulation of short-term neuroplasticity in the visual cortex induced by transcranial direct current stimulation

2008 ◽  
Vol 25 (1) ◽  
pp. 77-81 ◽  
Author(s):  
LEILA CHAIEB ◽  
ANDREA ANTAL ◽  
WALTER PAULUS
Keyword(s):  
Sex Differences ◽  
Visual Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Cortical Excitability ◽  
Gonadal Hormones ◽  
Study Data ◽  
Short Term ◽  
Direct Current Stimulation ◽  
Significant Difference

Transcranial direct current stimulation (tDCS) is a non-invasive method of modulating levels of cortical excitability. In this study, data gathered over a number of previously conducted experiments before and after tDCS, has been re-analyzed to investigate correlations between sex differences with respect to neuroplastic effects. Visual evoked potentials (VEPs), phosphene thresholds (PTs), and contrast sensitivity measurements (CSs) are used as indicators of the excitability of the primary visual cortex. The data revealed that cathodally induced excitability effects 10 min post stimulation with tDCS, showed no significant difference between genders. However, stimulation in the anodal direction revealed sex-specific effects: in women, anodal stimulation heightened cortical excitability significantly when compared to the age-matched male subject group. There was no significant difference between male and female subjects immediately after stimulation. These results indicate that sex differences exist within the visual cortex of humans, and may be subject to the influences of modulatory neurotransmitters or gonadal hormones which mirror short-term neuroplastic effects.

Transcranial direct current stimulation combined with integrative speech therapy in a child with cerebral palsy: A case report

2016 ◽  
Vol 20 (2) ◽  
pp. 252-257 ◽  
Author(s):  
Vania L.C. Carvalho Lima ◽  
Luanda A. Collange Grecco ◽  
Valéria C. Marques ◽  
Felipe Fregni ◽  
Clara R. Brandão de Ávila
Keyword(s):  
Cerebral Palsy ◽  
Case Report ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Speech Therapy ◽  
Direct Current Stimulation

scholarly journals Gambling disorder and bilateral transcranial direct current stimulation: A case report

2018 ◽  
Vol 7 (3) ◽  
pp. 834-837 ◽  
Author(s):  
Giovanni Martinotti ◽  
Eleonora Chillemi ◽  
Matteo Lupi ◽  
Luisa De Risio ◽  
Mauro Pettorruso ◽  
...  
Keyword(s):  
Case Report ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Gambling Disorder ◽  
Direct Current Stimulation
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