Psycho-Vegetative Status and Plasma Catecholamines in the Men with Acute Coronary Syndrome

10.12737/5922 ◽  
2014 ◽  
Vol 21 (3) ◽  
pp. 146-149
Author(s):  
Алексеев ◽  
D. Alekseev ◽  
Лиман ◽  
T. Liman ◽  
Виноградов ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Acute Coronary Syndrome ◽  
High Frequency ◽  
Depressive Disorders ◽  
Frequency Component ◽  
High Frequency Component ◽  
Coronary Syndrome ◽  
Fatal Myocardial Infarction

The authors analyzed the manifestations of anxiety and depressive disorders, disturbance of autonomic regulation and changes in the level of catecholamines in the blood of patients with acute coronary syndrome from the perspective of outcomes of the disease. 102 men with a diagnosis of acute coronary syndrome were examined. Blood samples for the determination of catecholamines (epinephrine, norepinephrine, dopamine) was performed at admission, psychological examination and scrutiny of heart rate variability was performed on the third-fourth day of the hospitalization. All patients were divided into three groups. The first group was executed on 14 (13,7%) patients who had fatal myocardial infarction developed during hospitalization. In the second group there were 40 (47,1%) patients with non-fatal myocardial infarction. The third group included 48 (47,1%) patients with unstable angina. It was shown, that levels of anxiety and depression were inverse correlated with the concentration of dopamine in the plasma, and adrenaline levels are positively correlated with indicators of overall heart rate variability and its high frequency component. Thus, in patients with acute coronary syndrome, who developed myocardial infarction the incidence and severity of anxiety and depressive disorders is substantially lower than in patients with unstable angina. Increase in high frequency component of heart rate variability was more typical for patients with acute coronary syndrome who developed fatal myocardial infarction during hospitalization. High levels of dopamine in the blood plasma are typical for patients with nonfatal myocardial infarction.

scholarly journals THE EFFECTS OF AGOMELATINE ON HEART RATE VARIABILITY IN PATIENTS WITH ANXIETY-DEPRESSIVE DISORDERS WHO SUFFERED ACUTE CORONARY SYNDROME

2018 ◽  
Vol 33 (3) ◽  
pp. 36-45 ◽  
Author(s):  
T. M. Poponina ◽  
K. I. Gunderina ◽  
Yu. S. Poponina ◽  
M. V. Soldatenko
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Acute Coronary Syndrome ◽  
Sleep Quality ◽  
Mental Status ◽  
Depressive Disorders ◽  
Holter Monitoring ◽  
Coronary Syndrome ◽  
Group 2

Aim: to study the changes in heart rate variability (HRV) in patients with anxiety and depressive disorders who suffered acute coronary syndrome (ACS) and to determine the effects of antidepressant agomelatine on HRV and sleep quality during six-month follow up.Material and Methods. The study included 54 people with ACS, anxiety, and depressive disorders. Patients were randomly assigned to two groups. Antidepressant agomelatine 25 mg/day was administered to patients of group 1 in addition to standard therapy for ACS; group 2 received placebo. Twenty four-hour Holter ECG monitoring, HRV study, mental status monitoring, and sleep quality assessment were performed during hospitalization and at six-month follow up.Results. Patients of both groups had clinically significant anxiety, subclinical depression, and insomnia of varying severity. According to Holter monitoring data, all patients had decline in HRV parameters. After six months, anxiety and depression significantly improved in patients administered with agomelatine; these patients had sleep normalization and improved HRV. The comparison group did not have similar changes.Conclusion. Additional administration of agomelatine 25 mg/day to patients with anxiety and depressive disorders after ACS resulted in improvement of mental status, heart rate variability, and sleep quality. Due to the absence of pro-arrhythmogenic effects, administration of agomelatine allows to correct anxiety-depressive disorders in patients with ACS.

scholarly journals Heart Rate Variability Using The Analgesia Nociception Index as A Predictor of Illness Severity and Mortality in Critically Ill Patients with COVID-19.

2020 ◽  
Author(s):  
Cristian Aragón-Benedí ◽  
Pablo Oliver-Forniés ◽  
Felice Galluccio ◽  
Ece Yamak Altinpulluk ◽  
Tolga Ergonenc ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
High Frequency ◽  
Frequency Component ◽  
High Frequency Component ◽  
Autonomic Nervous

Abstract Introduction A balance between the autonomic nervous system and the immune system against SARS-COV-2 is critical in the resolution of its severe macrophage proinflammatory activation. To demonstrate that most severely ill COVID-19 patients will show a depletion of the sympathetic nervous system and a predominance of parasympathetic tone. We hypothesized that a low energy of an autonomic nervous system and a high level of the high frequency component of heart rate variability may be related to the number of proinflammatory cytokines and could have a predictive value in terms of severity and mortality in critically ill patients suffering from COVID-19; Materials and Methods Single-centre, prospective, observational pilot study which included COVID-19 patients admitted to the Surgical Intensive Care Unit. High frequency (HF) component of heart rate variability (HRV) and energy of the autonomic nervous system were recorded using analgesia nociception index monitor (ANI). To estimate the severity and mortality we used the SOFA score and the date of discharge or date of death.Results A total of fourteen patients were finally included in the study. High-frequency component of heart rate variability (ANIm) were higher in the non-survivor group (p = 0.003) and were correlated with higher IL-6 levels (p = 0.002) Energy was inversely correlated with SOFA (p = 0.029). Limit value at 80 of ANIm, predicted mortalities with the sensitivity of 100% and specificity of 85.7%. In the case of energy, a limit value of 0.41 predicted mortality with all predictive values of 71.4%.Conclusion The different components of the spectral analysis of HRV allow us to infer the association between the autonomic nervous system and critically ill patients’ immune system. A low autonomic nervous system activity and a predominance of the parasympathetic system due to sympathetic depletion in patients are associated with a worse prognosis and higher mortality.

Relation between Major and Minor Depression and Heart Rate, Heart-Rate Variability, and Clinical Characteristics of Patients with Acute Coronary Syndrome

2007 ◽  
Vol 100 (3_suppl) ◽  
pp. 1245-1254 ◽  
Author(s):  
Katija Čatipović-Veselica ◽  
Andrea Galić ◽  
Krešimir Jelić ◽  
Vedrana Baraban-Glavaš ◽  
Sandra Šarić ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Acute Coronary Syndrome ◽  
Clinical Characteristics ◽  
Minor Depression ◽  
St Segment Elevation ◽  
Coronary Syndrome ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment

This study examined the prevalence of major and minor depression in patients with acute coronary syndrome and their relation with heart rate and heart-rate variability, and clinical characteristics. The study group included 297 patients, 200 men and 97 women, between ages of 21 and 70 years ( M age = 57.5 ± 9.6), who were admitted to a coronary care unit with acute coronary syndrome and survived to discharge from the hospital. Major and minor depression were diagnosed using DSM-IV. There were 44.1% patients with acute coronary syndrome without depression, 29.3% with minor depression, and 26.6% with major depression. The prevalence of minor and major depression was more elevated in patients with non-ST-segment elevation myocardial infarction and unstable angina than in patients with ST-segment elevation myocardial infarction. Ventricular fibrillation and atrial fibrillation were more common in patients with major and minor depression than in patients without depression. The 24-hr. duration of heart-beat intervals and heart-rate variability were significantly lower in patients with major and minor depression than in patients without depression. This study implies that clinical depression was significantly comorbid with the acute coronary syndrome and was related to hypertension, diabetes mellitus, age, sex, type of acute coronary syndrome, left ventricular failure, higher heart rate, and lower heart-rate variability.

scholarly journals DYNAMICS OF HEART RATE VARIABILITY UNDER THE INFLUENCE OF COURSE YOGA BREATHING EXERCISES ON HEALTHY YOUNG PEOPLE

2019 ◽  
Vol 72 (4) ◽  
pp. 613-616 ◽  
Author(s):  
Nataliia I. Sheiko ◽  
Volodymyr P. Feketa
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Cardiac Rhythm ◽  
Low Frequency ◽  
Frequency Component ◽  
High Frequency Component ◽  
Regulatory Activity ◽  
Biological Feedback ◽  
Very Low Frequency

Introduction: Heart rate variability is a highly informative non-invasive method of research not only for the functional state of the cardiovascular system and also for the integrative regulatory activity of the autonomic nervous system. The positive effect of diaphragmatic breathing is positive in the mode of biological feedback using portable devices, but there is little evidence of the use of yoga breathing gymnastics in order to influence the heart rate variability. The aim: To compare the possibilities of using courses of breathing gymnastics of yogis and diaphragmatic breathing sessions in the mode of biological feedback using a portable device. Materials and methods: The study involved 70 practically healthy foreigners, who were divided into 2 groups of 35 people. Participants of the 1st group daily engage in respiratory exercises pranayama for 15 minutes in 1 month. Participants in the 2nd group used the MyCalmBeat portable device. Heart rate variability was registered by using the computer diagnostic complex “CardioLab” (“KhAI-Medika”, Ukraine). Results: In both groups there was similar dynamics of heart rate variability indices, but its severity was different. The common integral effect was a significant growth of heart rate variability both according to statistical and spectral indicators – total power increased, as well as high-frequency component. The power of the very-low frequency waves has probably decreased only in the group with the device. In the percentage structure of the cardiac rhythm spectrum, the specific weight of very-low frequency component and the percentage of high-frequency component increased. Conclusions: Respiratory gymnastics yoga for 15 minutes daily contributes to the growth of heart rate variability through the suppression of the central link (very-low frequency component) of regulation of cardiac rhythm and increased activity of parasympathetic influences (high-frequency component), as well as the redistribution of regulatory activity of the central nervous system between the central and peripheral links of regulation of the cardiac rhythm in favor of the latter.

Sign in / Sign up

Export Citation Format

Share Document