Scientific Basis of the Use of Medical Rehabilitation and Botulinum Therapy during Rehabilitation Post-Stroke Spasticity

10.12737/3305 ◽  
2014 ◽  
Vol 21 (1) ◽  
pp. 25-29
Author(s):  
Королев ◽  
A. Korolev

Among the factors contributing to disability after stroke is the most important movement disorder, major clinical manifestation of which is the central spastic paresis. Spasticity is revealed in the study of passive movements of the limbs as increased resistance to muscle in response to its rapid stretching. Once developed spastic paresis usually persists throughout the life of the patient. The treatment of spastic paresis is intractable problem. In recent years the treatment of post-stroke spasticity started using botulinum toxin type A. In comparison with the existing methods of treating muscle hyper local administration of botulinum toxin has a number of obvious advantages. According to the latest recommendations in all cases after botulinum therapy require active physical therapy and physical rehabilitation. Botulinum therapy is not a substitute for physical therapy and exercise therapy, which is the basis of the rehabilitation program and is an integrated part of a comprehensive treatment to improve motor functions. Using a special additional treatment measures such as physical therapy and exercise therapy is often part of the overall treatment but their formal evaluation was carried out in only a few studies. The article presents the author´s concept of rehabilitation post-stroke spastic muscle hypertonus in neuro-rehabilitation with the use of medical rehabilitation and botulinum therapy.

2018 ◽  
Vol 10 (2) ◽  
Author(s):  
Antonio Prazeres ◽  
Marília Lira ◽  
Paula Aguiar ◽  
Larissa Monteiro ◽  
Ítalo Vilasbôas ◽  
...  

The aim was to investigate if botulinum toxin type A (BTx-A) associated with physical therapy is superior to physical therapy alone in post stroke spasticity. A randomized, double-blinded controlled trial was performed in a rehabilitation unit on Northeastern, Brazil. Patients with post stroke spasticity were enrolled either to BTx-A injections and a pre-defined program of physical therapy or saline injections plus physical therapy. Primary endpoint was functional performance evaluated through time up and go test, six minutes walking test and Fugl-Meyer scale for upper limb. Secondary endpoint was spasticity improvement. Confidence interval was considered at 95%. Although there was a significant decrease in upper limbs flexor tonus (P<0.05) in the BTx-A group, there was no difference regarding functional performance after 9 months of treatment. When analyzing gait speed and performance, both groups showed a significant improvement in the third month of treatment, however it was not sustained over time. Although BTx-A shows superiority to improve muscle tone, physical therapy is the cornerstone to improve function in the upper limbs of post stroke patients.


2002 ◽  
Vol 3 (2) ◽  
pp. 93-99 ◽  
Author(s):  
Peter Schnider ◽  
Ecaterina Moraru ◽  
Marion Vigl ◽  
Christian Wöber ◽  
Daniela Földy ◽  
...  

Author(s):  
Kevin E. Liang ◽  
Pham Vivian Ngo ◽  
Paul Winston

ABSTRACT:Successful management of focal spasticity requires access to botulinum toxin type A (BoNT-A) injections, physiotherapy, occupational therapy, and orthoses/bracing. To assess the quality of focal spasticity care across Canada, we sent a survey consisting of 22 questions to physiatrists involved in the management of outpatient spasticity. Thirty-four physiatrists from all 10 provinces responded to the survey. Wait time for BoNT-A treatment averaged 12.7 weeks from time of referral across Canada. More than 75% of patients faced barriers to obtaining physical therapy and orthoses. Access to best quality care for spasticity patients across Canada varies widely.


Toxicon ◽  
2013 ◽  
Vol 68 ◽  
pp. 112
Author(s):  
L. Gonçalves ◽  
L. Jacinto ◽  
S. Paradinha ◽  
J. Morais

2017 ◽  
Vol 8 (1) ◽  
pp. 106-111
Author(s):  
Larisa A Danilenko ◽  
Margarita B Belogurova ◽  
Alexander A Gayduk

The article describes the experience of medical rehabilitation of patients after a complex treatment of cerebellar medulloblastoma with metastases in the spinal cord membranes and substance. Substantiates the role of medical rehabilitation funds in correcting the effects of the disease, and cancer treatment, the essence of which is determined by the damage to the structure and function of various organs and systems. The most common effects of the three-treating medulloblastoma are postoperative deficits: ataxia and paresis; radiation myelopathy, polyneuropathy chemotherapy-induced, deformations of the skeletal system, reduced functional performance and adaptation. Actualized value of interdisciplinary interaction: oncologists, pediatricians, neurologists, orthopedists, medical rehabilitation specialists; phasing and integrated use of all available methods of rehabilitation. Presented personalized rehabilitation program to study techniques of individual lessons therapeutic exercises, therapeutic swimming, gidrokinezioterapii, procedures, motor praxis, training paretic muscles of the selected feedback, massage. It is shown that multimodal rehabilitation treatment of patients at high risk of being in remission, is effective in its action in assessing both subjective: improvement of health, emotional tone, sleep, increased appetite, and objective data: normalization of body weight, improving coordination and increasing the range of motion, increase muscle strength, strength endurance muscle corset. Currently, medical rehabilitation is an essential component of cancer patients routing.


2021 ◽  
Vol 11 (1) ◽  
pp. 122-133
Author(s):  
T. I. Grushina ◽  
S. O. Podvyaznikov ◽  
G. A. Tkachenko ◽  
A. M. Mudunov ◽  
S. B. Shakhsuvaryan ◽  
...  

Four stages of medical rehabilitation of patients with differentiated thyroid cancer in Russia are described. Specific rehabilitation programs and methods are described for every stage. The pre-rehabilitation program includes psychological and nutritional support, exercise therapy, consultations by the surgeon and anesthesiologist, correction of concomitant disorders, prevention of thromboembolic complications and local hemodynamic abnormalities. At the rehabilitation stage in the ICU antibacterial therapy, patient positioning, percussion massage of the chest, passive mobilization, massage of the extremities are performed. The rehabilitation program at the specialized surgical department includes psychological rehabilitation, adequate pain management, exercise therapy, massage, nutritional support, prevention of thromboembolic complications, treatment of early postoperative complications. The in-hospital rehabilitation at medical facilities additionally includes treatment of delayed and late surgical complications, correction of radioiodine therapy consequences. The outpatient rehabilitation program also involves correction of hypothyroidism and minimization of adverse effects of suppressive hormone therapy, health resort treatment.


Toxins ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 770
Author(s):  
Patricia Khan ◽  
Marcelo Riberto ◽  
João Amaury Frances ◽  
Regina Chueire ◽  
Ana Cristina Ferreira Garcia Amorim ◽  
...  

Botulinum toxin type A (BoNT-A) is an effective treatment for post-stroke spasticity; however, some patients cannot access treatment until ≥1 year post-stroke. This Brazilian post-marketing study (NCT02390206) assessed the achievement of person-centered goals in patients with chronic post-stroke spasticity after a BoNT-A injection. Patients had a last documented stroke ≥1 year before study entry and post-stroke upper limb (UL) spasticity, with or without lower limb (LL) spasticity. Patients received BoNT-A injections at baseline (visit 1) and visit 2 (3–6 months). Primary endpoint was responder rate (achievement of primary goal from Goal Attainment Scaling (GAS)) at visit 2. Overall, 204 patients underwent GAS evaluation at visit 2, mean (SD) age was 56.4 (13.2) years and 90.7% had LL spasticity. Median (range) time between first stroke and onset of spasticity was 3.6 (0−349) months, onset of spasticity and first injection was 22.7 (0−350) months and waiting time for a rehabilitation appointment was 9.0 (1−96) months. At visit 2, 61.3% (95% CI: 54.4, 67.7) of patients were responders, which was similar for UL and LL primary goals (57.8% [95% CI: 49.9, 65.3] vs. 64.1% [95% CI: 48.4, 77.3]). This study provides evidence to support the effectiveness of BoNT-A treatment for chronic post-stroke spasticity.


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