scholarly journals PREVALENCE OF SMOKING IN ADULT POPULATION OF IRKUTSK

2016 ◽  
Vol 1 (6) ◽  
pp. 153-156
Author(s):  
Максикова ◽  
Tatyana Maksikova ◽  
Бабанская ◽  
Evgeniya Babanskaya ◽  
Меньшикова ◽  
...  
Keyword(s):  
Risk Factor ◽  
Adult Population ◽  
Age Groups ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Noncommunicable Diseases ◽  
Age Difference ◽  
Age Group ◽  
Considerable Problem ◽  
The One

Smoking is a significant risk factor of chronic noncommunicable diseases. Smoking prevalence is variable in different populations. A study of the prevalence of this risk factor allows to estimate its contribution to the development of cardiovascular pathology, to plan the necessary amount of medical care for people using tobacco, and to determine the effectiveness of prevention activities in the region. As a result of the study, smoking frequency in population of the Irkutsk region older 18years of age or over was established as 29.5%. The number of smokers increased with age, reaching maximum value of 38.6% in the group 30–39 years. Male smokers made maximum in the age group 30–39 years, women – in the age group of 18–19 years. The average age of smokers was 34 years, the one of nonsmokers – 43 years. The age difference was 9 years, and it was lower in the group of men than in the group of women (5 and 11 years, respectively). The number of the smoking men were 3 times larger, than women: 50.2% and 13.5%, respectively. Among persons with arterial hypertension, 22.1% were smoking with the maximum frequency of smoking in age groups from 20 to 49 years. These figures point to a considerable problem of smoking in the region.

scholarly journals Definitions and Risk Factors for Drug-Resistant Epilepsy in an Adult Cohort

2021 ◽  
Vol 12 ◽  
Author(s):  
Alyssa Denton ◽  
Lilian Thorpe ◽  
Alexandra Carter ◽  
Adriana Angarita-Fonseca ◽  
Karen Waterhouse ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Risk Factor ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Drug Resistant ◽  
Age Group ◽  
Drug Resistant Epilepsy ◽  
New Diagnosis

Background: Less than one-third of people with epilepsy will develop drug-resistant epilepsy (DRE). Establishing the prognosis of each unique epilepsy case is an important part of evaluation and treatment.Most studies on DRE prognosis have been based on a pooled, heterogeneous group, including children, adults, and older adults, in the absence of clear recognition and control of important confounders, such as age group. Furthermore, previous studies were done before the 2010 definition of DRE by the International League Against Epilepsy (ILAE), so data based on the current definitions have not been entirely elucidated. This study aimed to explore the difference between 3 definitions of DRE and clinical predictors of DRE in adults and older adults.Methods: Patients with a new diagnosis of epilepsy ascertained at a Single Seizure Clinic (SSC) in Saskatchewan, Canada were included if they had at least 1 year of follow-up. The first study outcome was the diagnosis of DRE epilepsy at follow-up using the 2010 ILAE definition. This was compared with 2 alternative definitions of DRE by Kwan and Brodie and Camfield and Camfield. Finally, risk factors were analyzed using the ILAE definition.Results: In total, 95 patients with a new diagnosis of epilepsy and a median follow-up of 24 months were included. The median age of patients at the diagnosis of epilepsy was 33 years, and 51% were men. In the cohort, 32% of patients were diagnosed with DRE by the Kwan and Brodie definition, 10% by Camfield and Camfield definition, and 15% by the ILAE definition by the end of follow-up. The only statistically significant risk factor for DRE development was the failure to respond to the first anti-seizure medication (ASM).Conclusion: There were important differences in the percentage of patients diagnosed with DRE when using 3 concurrent definitions. However, the use of the ILAE definition appeared to be the most consistent through an extended follow-up. Finally, failure to respond to the first ASM was the sole significant risk factor for DRE in the cohort after considering the age group.

scholarly journals The 5-Factor Modified Frailty Index Predicts Complications and Worsening After Meningioma Surgery in Non-elderly Rather Than Elderly Patients: A Nationwide Registry Study

2021 ◽  
Author(s):  
Fusao Ikawa ◽  
Nobuaki Michihata ◽  
Soichi Oya ◽  
Toshikazu Hidaka ◽  
Shingo Matsuda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Elderly Patients ◽  
Frailty Index ◽  
Age Groups ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Nationwide Registry ◽  
Modified Frailty Index ◽  
Meningioma Surgery

Abstract The simplified 5-factor modified frailty index (mFI-5) is a useful indicator of outcome for patients undergoing surgeries and considered as an important risk factor in elderly patients. However, its usefulness has not been validated based on age groups. We aimed to investigate the risk factors including the mFI-5 across age groups for complications and worse outcomes in meningioma surgery using data obtained from the nationwide database in Japan. We extracted data from the nationwide registry database in Japan between 2010 and 2015. Age (< 65, 65–74, and ≥ 75 years), sex, Barthel Index (BI), mFI-5 scores, and complications were evaluated. Multivariate logistic regression analyses identified risk factors across all age groups for worsening BI scores and complications after surgery. In 8,138 included cases, an mFI-5 score ≥ 2 items was a significant risk factor for worsening BI scores in patients aged < 65 years (odds ratio: 2.00; 95% confidence interval: 1.31-3.06), but not in patients aged 65-74 years and those aged ≥ 75 years. Similar results were noted for complications in patients aged < 65 years (2.40; 1.67–3.44), but not in patients aged 65-74 years and those aged ≥ 75 years. In conclusion, the mFI-5 scores can predict the risk of worsening outcome and complications in non-elderly patients aged < 65 years rather than in elderly patients aged ≥ 65 years. In meningioma surgeries, care must be taken when making decisions using the mFI-5 scores based on the patients’ age.Trial RegistrationName: Study on treatment method, age group, complications, and outcome of meningiomas and hemangioblastomas using DPC, URL: http://www.umin.ac.jp/ctr/index-j.htmID: UMIN000038486, No.: R000043856

scholarly journals Obesity, A Risk Factor for Mortality in SARS CoV-2 Infection: A Narrative Systematic Review

2021 ◽  
Author(s):  
Sekhar Reddy ◽  
Mohd Ashraf Ganie ◽  
Parvaiz A. Koul ◽  
Tajali Sahar ◽  
Shaista Showkat
Keyword(s):  
Risk Factor ◽  
Independent Risk Factor ◽  
Elderly Population ◽  
Age Groups ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
The Elderly ◽  
Epidemiological Studies ◽  
Novel Coronavirus ◽  
Key Terms

AbstractSARS CoV-2 is a β-coronavirus responsible for the current COVID-19 pandemic. Although there is increase severity and mortality described in the elderly population and people with co-morbidities, all age groups are susceptible to COVID-19. Recent data showed that obesity has also emerged as a significant risk factor for COVID-19 mortality. As per the WHO, most of the world's population lives in countries where obesity is highly prevalent. In this context, we aimed to review various studies that showed obesity as an independent risk factor for mortality in SARS CoV-2 infection. We followed the PRISMA guidelines to search for two databases including PubMed and Google Scholar using the key terms “COVID-19, OBES* and MORTALITY,” SARS CoV-2, OBES* and MORTALITY” “COVID-19, OBESITY, and MORTALITY,” SARS Cov-2, OBESITY and MORTALITY,” respectively, up to August 3, 2020. Twelve studies were finally included in this review after applying inclusion and exclusion criteria. All 12 studies included in the review consistently showed that obesity is a risk factor for mortality in patients with SARS CoV-2 infection. These studies have also shown evidence that obesity leads to increased hospitalization, ICU admission, increased need for mechanical ventilation, and poor prognosis among patients with SARS CoV-2 infection. Obesity is an independent risk factor for mortality in patients infected with this novel coronavirus. Appropriate triage, monitoring, and vigilance are required while dealing with individuals with obesity with SARS CoV2 infection, especially in the young obese population. More epidemiological studies need to be done taking BMI also into consideration in COVID-19 patients to find the exact cause of increased severity and mortality and develop appropriate preventive and therapeutic strategies.

Abstract 17276: Impact of Cardiovascular Comorbidities on COVID-19 Infection Risk

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
David Tofovic ◽  
Minji Seok ◽  
Logan S Schwarzman ◽  
Sreenivas Konda ◽  
Noreen T Nazir
Keyword(s):  
Risk Factors ◽  
Cohort Analysis ◽  
Age Groups ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Age Group ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
Patient Demographics ◽  
The Impact

Introduction: A disproportionate amount of COVID-19 infections has occurred in minority populations and in individuals with comorbid disease. We sought to evaluate the impact of patient demographics, cardiovascular disease (CVD), and known CVD risk factors on the incidence of COVID-19 infection. Methods: Between April 1st to May 1st, 2020, 844 adult patients (mean age 51.4±17.7 years, mean BMI 29.6±8.3, 50% male) admitted for any reason and tested for COVID-19 based on CDC criteria were studied in this large, metropolitan, single-center retrospective cohort analysis. Bivariate and multivariate analysis between patient demographics, CVD, and CVD risk factors with COVID-19 were evaluated. The nonlinear effects of age on COVID-19 test results were further analyzed. Results: Prevalence of COVID-19 was 21.7%. African Americans, Latinos, and Caucasian were 463(55%), 216(25%), 165(20%) respectively. Unadjusted, diabetes mellitus (DM) was significantly related with the COVID-19 positivity (OR 1.83, 95% CI 1.30-2.58, P=0.0005), but age adjusted DM was insignificant (OR 1.35, 95% CI 0.93-1.97, P=0.12). Similar results were found with other CVD risk factors (see Tables 1,2). Stratified analysis by age groups (18-40 years, ≥40 years), DM in the younger age group was the most significant risk factor for the COVID-19 positivity (OR 4.52, 95% CI 1.95-10.52, P=0.0002) but not in older inpatients (OR 1.23, 95% CI 0.85-1.81, P=0.2763). In the older age group, Latinos were significantly higher risk for COVID-19 compared to Caucasian (OR 2.27, 95% CI 1.26-4.07, P=0.005). Conclusions: Increased resources for testing in younger individuals with DM and the Hispanic population may be merited.

scholarly journals Different tissue type categories of overuse injuries to cricket fast bowlers have different severity and incidence which varies with age

2016 ◽  
Vol 27 (4) ◽  
pp. 108 ◽  
Author(s):  
P Blanch
Keyword(s):  
Risk Factor ◽  
Sports Injuries ◽  
Age Groups ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Tendon Injury ◽  
Tissue Type ◽  
Bone Stress ◽  
Stress Injuries ◽  
Severity Of Injury

Background. Cricket fast bowlers have a high incidence of injury and have been the subject of previous research investigating the effects of previous injury, workload and technique. Bone stress injuries are of particular concern as they lead to prolonged absences from the game, with younger bowlers appearing to be at particular risk. Objectives. To investigate the variation in severity and incidence of injury to different tissue types in fast bowlers and ascertain whether age is a significant risk factor for these injuries. Methods. A retrospective analysis of match bowling exposure in 215 separate fast bowlers over a 14-year period was undertaken. This information was amalgamated with injury surveillance data providing information on the incidence, location, tissue type and severity of injury. Age of the bowler was determined and the bowlers were stratified into five age groups to determine the influence of age on the injury variables. Results. Younger bowlers (less than 22 years old) were 3.7-6.7 times more likely to suffer a bony injury than all the other age groups. Older bowlers (greater than 31 years old) were 2.2-2.7 times more likely to suffer a tendon injury than the 3 youngest groups. Conclusion. This study has demonstrated that younger age is a considerable risk factor in the development of bone stress injuries in cricket fast bowlers. In addition there appears to be a higher incidence of tendon injuries in older fast bowlers although this may be explained by the current classification system of joint impingement as a tendon injury. Keywords. Bone, tendon, sports injuries

scholarly journals Descriptive epidemiology of African horse sickness in Zimbabwe

2013 ◽  
Vol 80 (1) ◽  
Author(s):  
Stuart Gordon ◽  
Charlotte Bolwell ◽  
Chris Rogers ◽  
Alan Guthrie ◽  
Forgivemore Magunda ◽  
...  
Keyword(s):  
Risk Factor ◽  
Age Groups ◽  
Significant Risk ◽  
Case Fatality ◽  
Significant Risk Factor ◽  
Vaccination Status ◽  
African Horse Sickness ◽  
Descriptive Epidemiology ◽  
Vaccination Strategies ◽  
Review Current

A study of the prevalence of African horse sickness in horses was conducted, using records from two private equine practices in Harare for the period 1998–2004. Results indicated a higher prevalence of the disease in horses in Zimbabwe in the late rainy season (March – May). Age of the horse was found to be a significant risk factor, with foals or yearlings appearing to be 1.80 times more likely to contract the disease compared with horses older than two years. The case fatality rate in foals or yearlings was also higher than in older age groups, but this difference was not significant. The vaccination status was an important risk factor, with vaccinated horses 0.12 times less likely to die from the disease compared with unvaccinated horses. Young, unvaccinated horses therefore seem to be the most susceptible to the disease and have greater chances of fatality. This study highlights the importance of adequately protecting horses against African horse sickness by providing immunisation through vaccination and discusses the need to review current vaccination strategies being practiced in Zimbabwe.

scholarly journals A PROSPECTIVE STUDY OF POSTOPERATIVE PULMONARY COMPLICATIONS FOLLOWING UPPER ABDOMINAL SURGERIES

2020 ◽  
pp. 10-13
Author(s):  
Harshavardhan Harshavardhan ◽  
Poovarasan S ◽  
Harishchandra B
Keyword(s):  
Risk Factor ◽  
Pleural Effusion ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Pulmonary Complications ◽  
Age Group ◽  
Obstructive Disease ◽  
Breath Sounds ◽  
Increased Risk ◽  
Upper Abdominal

Aim: The aim of the study is to follow prospectively a group of patients undergoing elective upper abdominal surgeries and to observe those developing pulmonary complications post-operatively along with factors associated with an increased risk of developing post-operative pulmonary complications using a standard preoperative and postoperative evaluation.Method:Total of 110 patients admitted with upper abdominal pathologies undergoing elective upper abdominal surgeries in the department of General Surgery,during the period of October 2016 to October 2018 were observed for any pulmonary complications. Results:Study had 51 females and 59 males.38 patients developed PPC,19 were males and 19 females. The age distribution of these patients are 14 out of 38 patients(14%) were in the age group of 21-40 years, 16 out of 38 patients(16%) were in the age group of 41-60 years, 8 out of 38 patients(8%) were in the age group of more than 60 years. Out of 38 patients who developed PPC 15(60.5%) were smokers and 23(39.5%) were non-smokers. 21(55.3%) were underweight,14(36.8%) were normal weight,2 (5.3%) were overweight and 1 (2.6%) was class II obesity. 25(65.8%) had normal preoperative PFT, 6(15.8%) patients had mild obstructive disease,4(10.5%) had moderate obstructive disease and 3(7.9%) had restrictive disease. Among 38 patients with PPC 7(18.4%) had gastric surgeries,4(10.5%) had liver surgeries,9(23.7%) underwent surgeries on gall bladder and CBD, 17(44.7%) had pancreatic surgeries,1(2.6%) had surgery on spleen.Among 38 patients who developed PPC all of them had cough with sputum and raised WBC count,32 had fever,37 had abnormal breath sounds,2 had decreased oxygen haemoglobin saturation less than 90%,13(34.2%) patients had unilateral pleural effusion,10(26.3%) had bilateral pleural effusion,3(7.9%) had unilateral consolidation and 12(31.6%) had normal chest x-ray and 11(10%) had positive sputum culture.Conclusion:Patients undergoing upper abdominal surgeries are at a higher risk of developing Postoperative pulmonary complications.Age and Sex are not the significant risk factors for developing PPC.There is a significant correlation between the altered pre-operative pulmonary functions diagnosed by pulmonary function tests and developing PPC.BMI is not a significant risk factor to determine occurrence of PPC.Smoking may not be a significant risk factor to develop PPC.There is a significant relation between the type of upper abdominal surgery and the occurrence of PPC.Cough with sputum ,Fever and Abnormal breath sounds are the most common signs and symptoms seen in patients developing PPC.Pleural effusion is the most common radiological evidence of pulmonary pathology seen in patients with PPC.All patients with postoperative positive sputum culture developed PPC.

Physical Illness and Suicide Risk in Rural Residents of Contemporary China

Crisis ◽  
2014 ◽  
Vol 35 (5) ◽  
pp. 330-337 ◽  
Author(s):  
Cun-Xian Jia ◽  
Lin-Lin Wang ◽  
Ai-Qiang Xu ◽  
Ai-Ying Dai ◽  
Ping Qin
Keyword(s):  
Risk Factor ◽  
Family Income ◽  
Rural China ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Health Condition ◽  
Physical Illness ◽  
Rural Residents ◽  
Increased Risk ◽  
Study Population

Background: Physical illness is linked with an increased risk of suicide; however, evidence from China is limited. Aims: To assess the influence of physical illness on risk of suicide among rural residents of China, and to examine the differences in the characteristics of people completing suicide with physical illness from those without physical illness. Method: In all, 200 suicide cases and 200 control subjects, 1:1 pair-matched on sex and age, were included from 25 townships of three randomly selected counties in Shandong Province, China. One informant for each suicide or control subject was interviewed to collect data on the physical health condition and psychological and sociodemographic status. Results: The prevalence of physical illness in suicide cases (63.0%) was significantly higher than that in paired controls (41.0%; χ2 = 19.39, p < .001). Compared with suicide cases without physical illness, people who were physically ill and completed suicide were generally older, less educated, had lower family income, and reported a mental disorder less often. Physical illness denoted a significant risk factor for suicide with an associated odds ratio of 3.23 (95% CI: 1.85–5.62) after adjusted for important covariates. The elevated risk of suicide increased progressively with the number of comorbid illnesses. Cancer, stroke, and a group of illnesses comprising dementia, hemiplegia, and encephalatrophy had a particularly strong effect among the commonly reported diagnoses in this study population. Conclusion: Physical illness is an important risk factor for suicide in rural residents of China. Efforts for suicide prevention are needed and should be integrated with national strategies of health care in rural China.

scholarly journals Higher premature atrial complex burden from the Holter examination predicts poor cardiovascular outcome

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ting-Chun Huang ◽  
Po-Tseng Lee ◽  
Mu-Shiang Huang ◽  
Pei-Fang Su ◽  
Ping-Yen Liu
Keyword(s):  
Risk Factor ◽  
Dose Response ◽  
Cox Model ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Cardiovascular Death ◽  
Specific Model ◽  
Distribution Model ◽  
All Cause Mortality ◽  
Quartile Group

AbstractPremature atrial complexes (PACs) have been suggested to increase the risk of adverse events. The distribution of PAC burden and its dose–response effects on all-cause mortality and cardiovascular death had not been elucidated clearly. We analyzed 15,893 patients in a medical referral center from July 1st, 2011, to December 31st, 2018. Multivariate regression driven by ln PAC (beats per 24 h plus 1) or quartiles of PAC burden were examined. Older group had higher PAC burden than younger group (p for trend < 0.001), and both genders shared similar PACs distribution. In Cox model, ln PAC remained an independent risk factor for all-cause mortality (hazard ratio (HR) = 1.09 per ln PAC increase, 95% CI = 1.06‒1.12, p < 0.001). PACs were a significant risk factor in cause-specific model (HR = 1.13, 95% CI = 1.05‒1.22, p = 0.001) or sub-distribution model (HR = 1.12, 95% CI = 1.04‒1.21, p = 0.004). In ordinal PAC model, 4th quartile group had significantly higher risk of all-cause mortality than those in 1st quartile group (HR = 1.47, 95% CI = 1.13‒1.94, p = 0.005), but no difference in cardiovascular death were found in competing risk analysis. In subgroup analysis, the risk of high PAC burden was consistently higher than in low-burden group across pre-specified subgroups. In conclusion, PAC burden has a dose response effect on all-cause mortality and cardiovascular death.

scholarly journals Correlation between age, sex, and severity of Coronavirus disease-19 based on chest computed tomography severity scoring system

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Shimaa Farghaly ◽  
Marwa Makboul
Keyword(s):  
Computed Tomography ◽  
Scoring System ◽  
Fatal Outcome ◽  
Age Groups ◽  
Significant Risk ◽  
Chest Ct ◽  
Age Group ◽  
Severity Scoring ◽  
Chest Computed Tomography ◽  
Severity Of The Disease

Abstract Background Coronavirus disease 2019 (COVID-19) is the most recent global health emergency; early diagnosis of COVID-19 is very important for rapid clinical interventions and patient isolation; chest computed tomography (CT) plays an important role in screening, diagnosis, and evaluating the progress of the disease. According to the results of different studies, due to high severity of the disease, clinicians should be aware of the different potential risk factors associated with the fatal outcome, so chest CT severity scoring system was designed for semi-quantitative assessment of the severity of lung disease in COVID-19 patients, ranking the pulmonary involvement on 25 points severity scale according to extent of lung abnormalities; this study aims to evaluate retrospectively the relationship between age and severity of COVID-19 in both sexes based on chest CT severity scoring system. Results Age group C (40–49 year) was the commonest age group that was affected by COVID-19 by 21.3%, while the least affected group was group F (≥ 70 years) by only 6.4%. As regards COVID-RADS classification, COVID-RADS-3 was the most commonly presented at both sexes in all different age groups. Total CT severity lung score had a positive strong significant correlation with the age of the patient (r = 0.64, P < 0.001). Also, a positive strong significant correlation was observed between CT severity lung score and age in both males and females (r = 0.59, P < 0.001) and (r = 0.69, P < 0.001) respectively. Conclusion We concluded that age can be considered as a significant risk factor for the severity of COVID-19 in both sexes. Also, CT can be used as a significant diagnostic tool for the diagnosis of COVID-19 and evaluation of the progression and severity of the disease.

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