PATHOGENETIC MARKERS OF ECOLOGICALLY RELATED RESPIRATORY DISEASES

2016 ◽  
Vol 1 (62) ◽  
pp. 8-15 ◽  
Author(s):  
Татьяна Виткина ◽  
Tatyana Vitkina ◽  
Людмила Веремчук ◽  
Lyudmila Veremchuk ◽  
Ирина Симонова ◽  
...  

The aim of the research is to examine the relationship between the integral parameters of respiratory function, the values of LPO-AOD system and NO level at bronchopulmonary pathology in individuals living in different ecological areas of the city of Vladivostok. 206 patients living in different ecological conditions (healthy individuals, patients with respiratory disorders) were examined. Lung function and the state of LPO-AOD system were studied; the concentration of NO metabolites was assessed in blood serum. The nature and strength of the impact of environmental factors on respiratory function, the state of LPO-AOD, NO level were studied by the method based on correlation analysis. There was calculated power index (D) which was differentiated into power within the system (Ds) which in its turn reflects the in-system interrelationship tension (LPO-AOD, respiratory) and power between systems (Dm) characterizing the activity of interconnections and response to an external stimulus. Intra-system dependences typical for the unfavorable zone were viewed in relation to the favorable zone. It was found out that in ecologically unfavorable regions in individuals with different bronchopulmonary pathologies the value of Ds increases. This indicates that the pathogenic influence of environmental factors increases. In healthy people living in ecologically unfavourable area physiological adaptive-compensatory reaction of the body was revealed, which was proved by high power interconnections (Dm). In the patients with chronic bronchitis there was maintained an adequate level of functioning of the body systems studied. In patients with COPD living in an unfavourable zone there were found strong links between the indicators of the system of LPO-AOD and of NO, and in patients with bronchial asthma - supplementary relationship between lung function and NO. At the same time pathologic changes in the system of LPO-AOD and NO depend on the general pollution, metal and gas components contained in the air. Thus, the people with respiratory diseases being in environmentally unfavorable conditions have the most negative influence. The analysis of the activity of relationships proved that violations of interaction of LPO-AOD systems and NO in ecologically unfavorable regions may contribute to the occurrence and progression of bronchopulmonary diseases.

Author(s):  
Sri Pateda ◽  
Masayuki Sakakibara ◽  
Koichiro Sera

The evaluation of mercury impact on humans is currently nonspecific because the body characteristics (homeostasis) of each human being varies. Therefore, in the early diagnosis of mercury toxicity, one of the most important monitoring parameters is the respiratory function examination. In this study, respiratory function was examined with a portable spirometer and correlated with the mercury levels in hair from the noses and heads of subjects. Samples were taken from artisanal and small-scale gold mining (ASGM) areas (villages of East Tulabolo and Dunggilata) and control areas (villages of Bongo and Longalo) in Gorontalo Province, Indonesia. A statistical analysis with the Mann–Whitney test (alternative) showed significant differences in lung function between the polluted and control areas (α = 0.03). The analysis of nasal and head hair samples with particle-induced X-ray emissions (PIXE) showed that the mercury levels in the ASGM area were considerably higher than in the more homogeneous control areas. This study confirms that a pulmonary function test is a quick and precise alternative way to monitor the impact of mercury on humans, especially atmospheric mercury, because we detected a negative correlation between pulmonary function and the level of mercury in hair.


Author(s):  
Hiroshi Yamaguchi ◽  
Kandai Nozu ◽  
Shinya Ishiko ◽  
Atsushi Kondo ◽  
Takeshi Ninchoji ◽  
...  

The coronavirus disease (COVID-19) pandemic altered environmental factors. We studied the impact of these changes on asthma exacerbation (AE) by comparing the AE-related environmental factors between COVID-19 (2020) and pre-COVID-19 (2011–2019) eras. Between 2011 and 2020, 278,465 children (<16 years old) visited our emergency department, and 7476 were diagnosed with AE. The number of patients showed spring and fall peaks in 2011–2019. Multivariate analyses showed significant positive relationships of the number of AE patients with the average temperature among all patients and 0–5-year-olds and with sulfur dioxide (SO2) levels in 2011–2019 among 0–5-year-olds. Although the spring peak in the number of patients was not observed in 2020 after declaration of a state of emergency, the fall peak was again observed after the state of emergency was lifted. No changes in average temperature were detected, but SO2 was significantly reduced following declaration of the state of emergency in 2020. Therefore, SO2 reduction might have contributed to the disappearance of the peak of AE. However, a fall peak was observed again in 2020, although SO2 levels continued to be low. These data suggest that person to person interaction seems to be associated with AE, presumably due to unknown viral infections.


2018 ◽  
Vol 1 (1) ◽  
pp. 364
Author(s):  
Yanzah Bagas Nugraha ◽  
Dwi Andayani Budisetyowati

The establishment of the Regional Representative Council of the Republic of Indonesia so called Dewan Perwakilan Daerah (DPD-RI) at least has two objectives. The first is to enhance justice for the people in the region. Secondly, to expanding and increasing the participation of local communities in national life. The process to form this state institution is done by amending the 3rd amendment of the 1945 Constitution of the Republic Indonesia. However, in doing that  amendment there was an internal conflict within the body of DPD-RI involving the old and the new leaders of this institution last year. The length of leadership tenure which was initially made 5 years was amended to became 2.5 years. The different length of leadership tenure was then canceled by the Supreme Court and it was decided to be the same as other institution such as The People’s Consultative Assembly and The House of Representative in that the leadership tenure should be in accordance with the electoral cycle of 5 years. However, although the regulation of DPD-RI has been canceled, the Supreme Court keeps sending its representative to guide the oath of position of the new DPD-RI leadership. The only regulation that has been introduced by the state was regulation toward conflict between state institutions and this conflict can merely be resolved by the Constitutional Court. Therefore, there is an urgent need for the state to seek solution to solve this problem to prevent the same thing happened to other state institution in the future.


Author(s):  
Muammar

The impact of globalization has penetrated throughout the civilization of the nations of the world, running so fast. Especially very influential on changes in various lines of life. Related to this is the issue of increasing narcotics abuse and narcotics illicit trafficking which has created conditions that have hindered the development process and weakened civilization. Eradication of narcotics distribution is a national problem, because it has a negative impact that can damage and threaten the lives of the people, nation and state and can hamper the national development process. The rise of narcotics abuse does not only occur in big cities, but has reached small cities in all ten regions of the Republic of Indonesia, including East Aceh Regency. The increasingly diverse lifestyle of the people due to the influence of globalization also contributes to the increasing circulation of narcotics in East Aceh District. This certainly must receive serious attention, because if we look at what is happening in East Aceh District and several other regions in Indonesia, the crime of narcotics distribution from time to time always increases which in the end is increasingly unsettling the community, so before these things increase In East Aceh District, an effective solution must be found to eradicate it. Factors that cause a person to commit a narcotics crime in East Aceh Regency are due to economic factors where a person needs money to live and the difficulty of getting work, family environmental factors, social environmental factors and availability / lack of supervision factors. Efforts in tackling narcotics circulation in East Aceh district involve many parties, including: firstly, pre-emptive efforts by providing counseling in the community and schools about narcotics carried out by the police in tackling narcotics crime in East Aceh District. Second, preventive measures (prevention) by conducting raids and patrols routinely, providing oversight of the association and positive activities carried out by the police, prosecutors, religious leaders, community leaders and youth organizations. The third repressive effort (action) which aims to provide a deterrent effect on the perpetrators of drug trafficking crimes involving all law enforcement officials ranging from the Police, Attorney and District Courts and Detention Houses.Keywords: Crimonology, Narcotics Circulation. 


Author(s):  
SeyedehZahra Nozen ◽  
Bahman Amani ◽  
Fatemeh Ziyarati

“For masterpieces are not single and solitary births; they are the outcome of many years of thinking in common, of thinking by the body of the people, so that the experience of the mass is behind the single voice…”. Woolf’s belief has been put to the test in the Bloomsbury Group and this paper intends to investigate the validity of her claim through a critical analysis of the selected works of its novelist members. In a central part of London during the first half of the twentieth century a group of intellectual and literary writers, artists, critics and an economist came together which later on was labeled as Bloomsbury group. The group’s members had an influential role in blooming novel in a different form of expression and profoundly affect its literary figures, Virginia Woolf and E.M. Forster, in the composition of their fictions The Waves, A Room of One’s Own, To the Lighthouse and Forster’s A Room with a view and Howards End. The formation of Bloomsbury circle acted as a bridge from the Victorian bigotries and narrow-mindedness to the unbounded era of modernism as they searched for universal peace, individual liberalism and human accomplishments due to ideal social norms. They freely exchanged their views on variety of subjects without any limitation. The reasons behind their popularity compared to several contemporary groups were their innumerable works, the clarification of their lives through their diaries, biographies and autobiographies and their diverse kinds of activities such as criticism, painting, politics and literary writings. They were adherents of truth, goodness, enjoyment of beautiful object, intrinsic values, aesthetics, friendship and personal relationship. Intellectual intimacy and cooperation can be considered as the main attribute of its members as they collaborate with each other and employ the fundamental tenets of the group within their works. The modern style of its artists as post-impressionist highly affects the narration technique of its literary figures. These novelists tried to narrate the verbal utterances in a visual way as if the whole of the story is depicted on a canvas. Furthermore, this paper tries to discover the role of the non-literary (painters and critics) members of the group in blooming and forming of a different and novel kind of narration technique, namely ‘stream of consciousness’, through the visual impact of the painter and the discussion method of critic members of the group.


Author(s):  
Emilia MISZEWSKA ◽  
Maciej NIEDOSTATKIEWICZ ◽  
Radosław WIŚNIEWSKI

The popularity of Floating Homes in Western Europe and North America is noticeable. The interest in these facilities in Poland is also constantly growing. The popularity of Floating Homes is due to climate change, rising land prices and population density in city centers. However, environmental factors play a significant role in their development. The publication presents the results of research on the impact of environmental factors on the development of Floating Homes in Poland. As part of the research, the most important environmental factors were identified and then, using the State of the Surroundings Scenarios (SSS) method, an initial scenario of their development was developed. The most probable scenario was developed, the purpose of which was to identify the most favorable factors - strengths and unfavorable factors - weaknesses responsible for the development opportunities of Floating Homes in Poland. Additionally, a surprise scenario was prepared, which indicated factors that may unexpectedly accelerate the development of Floating Homes in Poland or slow it down.


2019 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Beni Dwi Komara ◽  
Agus Prasetya

Article 33 of the 1945 Constitution aspires to the Indonesian economy being managed by the state with the aim of the prosperity of the Indonesian people. But the fact is that prosperity is only enjoyed by certain people and certain groups because the economy is only controlled by those who are only a small part of the Indonesian people. The growth of super markets, modern retail stores such as IndoMart, AlfaMart in all corners of the country, both villages and cities, has displaced traditional markets and caused traditional traders to go out of business. This is a violation of the constitution and must be stopped. Traditional traders are populist economic actors in the economic system, so the state must not commit arbitrariness, such as allowing competition, unhealthy competition between traditional traders and modern retail traders. This study aims: a). Knowing the need for social construction to traditional traders, b). what is the impact of the presence of modern retailers on traditional markets, c). the response of traditional traders to the mushrooming of IndoMart and AlfaMart, d). How should the local government protect Traditional market traders. This study uses a qualitative approach, with its social paradigm of social definition. Data retrieval through in-depth interviews, observation, documentation, while data analysis uses Interactive Miles and Hubermann Models. The results of the study show that it was necessary to do "Social Reconstruction" to traditional traders. The presence of modern markets has resulted in declining sales levels, the flight of buyers from the “Sleko” market, “Besar” market, and other traditional markets. This condition creates an "economic shock" for traditional traders because they felt their territory is "robbed" by traders who have large capital. If this condition is left uncontrolled, it would create social insecurity, namely traders become unemployed, beggars, which shall trigger an increase in crime rates. Local governments must act quickly by doing "Social Trader Reconstruction Traditional". A policy that was oriented to the economy of the people to revive traditional markets and allow traditional traders to resell. Don't treat people only become social objects! Economy, politics of politicians and regional governments at certain times such as the regional elections and the presidential election


2018 ◽  
Vol 97 (2) ◽  
pp. 124-131 ◽  
Author(s):  
V. M. Prusakov ◽  
Aleksandra V. Prusakova

There were studied: The role of the disease dynamics at the background area in the formation of the risk for childhood morbidity in the study area; the value of indices of the long-term wavelike risk dynamics and the corresponding adaptation process for the identification and classification of mass non-infectious diseases. The waviness dynamics of the children morbidity risk is caused by the wave-like nature of the disease dynamics in the study and background areas. The disease risk level is formed not only by differences in the incidence rates of the background and study areas but also from differences in phases of high and low non-specific resistance of children contingent in these territories. The different character of the dynamics of the risk for the disease and related waviness of the adaptation process among children reflects the existence of differences in exposure to characteristics of local environmental factors in each territory. The average risk of disease, around which there are carried out annual fluctuations risks and phase states of the adaptation process, and the corresponding levels of reactivity and resistance of the body are the result of the absolute magnitude of the impact of local factors on the study area. The average relative risk of the morbidity, around which there are carried out annual fluctuations risks and phase states of the adaptation process is an integral index of the level of mass non-infectious diseases and the degree of severity of the medical and environmental situation, the level of reactivity and work mismatch of the body subsystems of children and the degree of their intensity. This is the measure of the absolute magnitude of the impact of local factors. The waviness to the development of states of high and low resistance is both always an index of antistress activation responses (or non-specifically high resistance state) and relative to the average force of impact factors (for the observed reactivity level). On the basis of the accounting for the level of the risk, there is suggested the classification of infectious diseases, including 1) the background or relatively satisfactory morbidity, 2) mass morbidity with the increased risk, 3) mass incidence of the high-risk, and 4) a mass incidence of the very high risk.


Author(s):  
Emmanuel Stephen N

Taxes<em> have been the bedrock of revenue generation to any government. The administration of tax is very important to any government as it is the body responsible for implementing and governing the tax laws and other tax related to assessment, collection and remittance of tax. This study is aimed at ascertaining the effect of tax administration on revenue generation in Gombe state. The study uses survey research design. The primary source of data collection was adopted, which analysed using descriptive statistics was made up of frequencies and simple percentages. Cronbach's Alpha diagnose was carried out to seek for reliability of the questions contained in the questionnaire Three Hypotheses were presented in this research and were tested using Spearman’s Rank correlation, Pearson correlation and linear regression. Research findings indicated that Tax Administration in the state is not efficient and effective. The study revealed further that revenue generated in the state is low to meet its objectives due to low level of enlightenment of tax payers and incidents of tax evasion and tax avoidance. To this end, the study recommends, among others, that authorities should embark on more enlightenment campaign of citizens on the significance of paying Personal Income Tax, the quality and efficiency of tax workers should be improved so that more effective administration will be achieved and automation of the system.</em>


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