The significance of oligohydramnios in the genesis of perinatal pathology

2016 ◽  
Vol 21 (32) ◽  
pp. 57-62
Author(s):  
Каркусова ◽  
Alla Karkusova ◽  
Бураева ◽  
Zarina Buraeva
Keyword(s):  
Blood Flow ◽  
Growth Retardation ◽  
Congenital Malformations ◽  
Perinatal Outcomes ◽  
Fetal Growth Retardation ◽  
Congenital Diseases ◽  
Perinatal Pathology ◽  
Placental Blood ◽  
Detailed Search ◽  
Placental Blood Flow

Perinatal pathology, including congenital malformations of the fetus, is a serious problem of today’s society. The purpose of this study was to identify the significance of oligohydramnios in the diagnosis of congenital diseases in children. The study involved 140 pregnant women aged 18 to 42 years. It was found that while simultaneous revealing of oligohydramnios, fetal growth retardation, abnormal cardiotocography types, hemodynamic disturbances in the utero-placental blood flow risk of having children with congenital malformations is increased by 1.5 times. Thus, a more detailed search for the ultrasonic markers of congenital diseases, timely consulting of families in medical genetics facilities while oligohydramnios allows to prevent severe perinatal outcomes.

scholarly journals 3D Doppler imaging of placental blood flow in prediction of fetal

2013 ◽  
Vol 62 (2) ◽  
pp. 160-165
Author(s):  
Marina Petrovna Fomina
Keyword(s):  
Blood Flow ◽  
Power Doppler ◽  
Doppler Imaging ◽  
Fetal Growth Retardation ◽  
Placental Dysfunction ◽  
3D Power Doppler ◽  
Placental Blood ◽  
Diagnostic Criterion ◽  
Placental Blood Flow ◽  
Singleton Pregnancies

Placental blood flow was studied in 103 women with singleton pregnancies at 7–15 weeks of gestation by 3D power Doppler. Reduced placental vasculature was revealed using 3D power Doppler at 7–15 weeks of gestation and it was defined as a diagnostic criterion of placental dysfunction and prognostic marker of fetal growth retardation.

scholarly journals Non-invasive evaluation of placental blood flow: lessons from animal models

Reproduction ◽  
2017 ◽  
Vol 153 (3) ◽  
pp. R85-R96 ◽  
Author(s):  
E Mourier ◽  
A Tarrade ◽  
J Duan ◽  
C Richard ◽  
C Bertholdt ◽  
...  
Keyword(s):  
Blood Flow ◽  
Animal Models ◽  
Ultrasound Contrast Agents ◽  
Valuable Insight ◽  
Non Invasive ◽  
Placental Blood ◽  
2D And 3D ◽  
Reliable Methods ◽  
Placental Blood Flow ◽  
Invasive Evaluation

In human obstetrics, placental vascularisation impairment is frequent as well as linked to severe pathological events (preeclampsia and intrauterine growth restriction), and there is a need for reliable methods allowing non-invasive evaluation of placental blood flow. Uteroplacental vascularisation is complex, and animal models are essential for the technical development and safety assessment of these imaging tools for human clinical use; however, these techniques can also be applied in the veterinary context. This paper reviews how ultrasound-based imaging methods such as 2D and 3D Doppler can provide valuable insight for the exploration of placental blood flow both in humans and animals and how new approaches such as the use of ultrasound contrast agents or ultrafast Doppler may allow to discriminate between maternal (non-pulsatile) and foetal (pulsatile) blood flow in the placenta. Finally, functional magnetic resonance imaging could also be used to evaluate placental blood flow, as indicated by studies in animal models, but its safety in human pregnancy still requires to be confirmed.

Effect of terbutaline sulphate on ovarian, uterine and maternal placental blood flow in the anaesthetized guinea pig

1978 ◽  
Vol 53 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Lena Mårtensson ◽  
Per-Ove B. Sjöquist ◽  
Leif Bjellin ◽  
Anthony M. Carter
Keyword(s):  
Blood Flow ◽  
Guinea Pig ◽  
Terbutaline Sulphate ◽  
Placental Blood ◽  
Placental Blood Flow

Fetal cardiac bypass alters regional blood flows, arterial blood gases, and hemodynamics in sheep

1992 ◽  
Vol 263 (3) ◽  
pp. H919-H928 ◽  
Author(s):  
S. M. Bradley ◽  
F. L. Hanley ◽  
B. W. Duncan ◽  
R. W. Jennings ◽  
J. A. Jester ◽  
...  
Keyword(s):  
Blood Flow ◽  
Blood Gases ◽  
Arterial Blood Gases ◽  
Blood Flows ◽  
Arterial Blood ◽  
Cardiac Bypass ◽  
Regional Blood Flows ◽  
Placental Blood ◽  
Fetal Organs ◽  
Placental Blood Flow

Successful fetal cardiac bypass might allow prenatal correction of some congenital heart defects. However, previous studies have shown that fetal cardiac bypass may result in impaired fetal gas exchange after bypass. To investigate the etiology of this impairment, we determined whether fetal cardiac bypass causes a redistribution of fetal regional blood flows and, if so, whether a vasodilator (sodium nitroprusside) can prevent this redistribution. We also determined the effects of fetal cardiac bypass with and without nitroprusside on fetal arterial blood gases and hemodynamics. Eighteen fetal sheep were studied in utero under general anesthesia. Seven fetuses underwent bypass without nitroprusside, six underwent bypass with nitroprusside, and five were no-bypass controls. Blood flows were determined using radionuclide-labeled microspheres. After bypass without nitroprusside, placental blood flow decreased by 25–60%, whereas cardiac output increased by 15–25%. Flow to all other fetal organs increased or remained unchanged. Decreased placental blood flow after bypass was accompanied by a fall in PO2 and a rise in PCO2. Nitroprusside improved placental blood flow, cardiac output, and arterial blood gases after bypass. Thus fetal cardiac bypass causes a redistribution of regional blood flow away from the placenta and toward the other fetal organs. Nitroprusside partially prevents this redistribution. Methods of improving placental blood flow in the postbypass period may prove critical to the success of fetal cardiac bypass.

scholarly journals HDliveFlow in the Assessment of Fetal Circulation

2015 ◽  
Vol 9 (4) ◽  
pp. 462-470 ◽  
Author(s):  
Suraphan Sajapala
Keyword(s):  
Blood Flow ◽  
Congenital Heart ◽  
Fetal Heart ◽  
Power Doppler ◽  
Future Research ◽  
Anatomical Landmarks ◽  
Fetal Circulation ◽  
4D Ultrasound ◽  
Placental Blood ◽  
Placental Blood Flow

ABSTRACT With the appearance of the latest three/four-dimensional (3D/4D) ultrasound machine (HDliveFlow, Voluson E10, GE Healthcare, Zipf, Austria), HDliveFlow with glass-body rendering mode or silhouette mode will facilitate more precise assessments of the fetal heart and peripheral circulation. The resolution of 3D/4D color/power Doppler using the HDlive technique shows a significant improvement compared to conventional 3D/4D color/power Doppler and the fetal heart with great vessels, small peripheral vessels, and placental blood flow can now be clearly recognized. HDliveFlow with glass-body rendering mode or silhouette mode combines the advantages of a spatial view of the great arteries in addition to the visualization of anatomical landmarks, such as the spine or diaphragm. Its use may provide potential advantages in cases of congenital heart anomalies and placental vascularity over the use of conventional 3D/4D color/power Doppler. This novel technique may assist in the evaluation of the fetal cardiovascular system and fetoplacental vascularity, and offer potential advantages relative to conventional 2D color/power Doppler assessments. In this article, we present the latest state-of-the-art HDliveFlow with glass-body rendering mode or silhouette mode of normal and abnormal fetal hearts, placentas, and umbilical cords. We also discuss the present and future applicability of 3D/4D color/ power Doppler to assess the fetal circulation. HDliveFlow with glass-body rendering mode or silhouette mode may become an important modality in future research on fetal cardiac and placental blood flow, and assist in the prenatal diagnosis of fetal congenital heart disease and placental vascular abnormalities. How to cite this article Hata T, AboEllail MAM, Sajapala S, Ito M. HDliveFlow in the Assessment of Fetal Circulation. Donald School J Ultrasound Obstet Gynecol 2015;9(4):462-470.

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