scholarly journals THE EFFICIENCY OF DRUG TSIMAKTIN USING FOR THE PREVENTION OF COWS POSTPARTUM COMPLICATIONS

2017 ◽  
Vol 2 (3) ◽  
pp. 46-50
Author(s):  
Мурат Баймишев ◽  
Murat Baymishev ◽  
Хайдар Сафиуллин ◽  
Haydar Safiullin ◽  
Хамидулла Баймишев ◽  
...  
Keyword(s):  
Blood Serum ◽  
Functional Status ◽  
Inflammatory Process ◽  
Reproductive Organs ◽  
Control Group ◽  
Hemoglobin Content ◽  
Biochemical Indicators ◽  
Homeopathic Medicine ◽  
Alkaline Reserve ◽  
General Protein

The purpose of researches is rising of efficiency of prophylaxis of cows patrimonial and puerperal pathologies. The current of cows labors and the puerperal period when using homeopathic medicine is studied Tsimaktin. It is estab-lished that drug Tsimaktin use reduces duration of cows current of labors in comparison with control by 1.87 hours. An involution of body and horns of experienced group uterus animals came to the end for 11.35 days earlier. Dis-turbances of involutional processes of control group cows reproductive organs to whom use didn't administer the drug 20% more Tsimaktin than at animals of experienced group. It is taped that drug Tsimaktin raises the morpho-functional status of cows organism that is confirmed by hematological and biochemical indicators of blood. The hemoglobin content, erythrocytes in control group cows blood after calvin was reliable less, than indicators of ani-mals of experienced group respectively on 15.09 g/l and on 1.94 1012 l. The indicator of the general protein in blood serum of experienced group cows is 2.69 g/l more than at cows of control group. The quantity of β-globulins after the delivery are more for cows of control group in comparison with experienced for 7,33% that indicates existence of inflammatory process in an organism of animals. Control group cows for 4-5 day the atsidotichesk state was after the delivery observed what the smaller indicator of an alkaline reserve on 3.38 ob%CO2 testifies to. Use of homeopathic medicine Tsimaktin in 25-30 days prior to labors allowed to raise cows fecundity and to reduce the number of days of sterility. Use of this drug is ecologically safe and allows to use milk without restrictions. On the basis of the conducted researches drug Tsimaktin can be recommended for prophylaxis of puerperal complications at cows.

THE APPLICATION OF BEER DRY PELLET IN YOUNG GOAT FODDER

2016 ◽  
Vol 1 (1) ◽  
pp. 33-36
Author(s):  
Захарова ◽  
Darya Zakharova ◽  
Зотеев ◽  
Vladimir Zoteev ◽  
Симонов ◽  
...  
Keyword(s):  
Blood Serum ◽  
Negative Impact ◽  
Control Group ◽  
Biochemical Indicators ◽  
Prime Cost ◽  
Economic Experiment ◽  
Exchange Processes ◽  
General Protein ◽  
The Cost ◽  
Protein Exchange

The purpose of research is to give an assessment to profitability of the beer dry pellet use in compound feeds for young goat stock. Scientific economic experiment has been made on young goats of Zaanen breed. Animals were divided into three groups, 6 heads in each. Compound feed of control group didn´t contain beer dry pellet (BDP), and the second experiment group feed contained 5.0% BDP (by weight), instead of oats and linen cake part parts, and the composition of compound feed for 3d group included 10.0% of BDP (by weight). During experiments it has been established that at experiment groups exchange processes proceeded more intensively. In blood serum of nanny-goats of experiment groups the content of the general protein exceeded control for 1.9-7.9%, the protein index (А\G coefficient), of animals 3d group was above control for 10.1%. Activity of ALT and AST aminotransfer which indicators were higher in experiment groups by comparison with the control also testifies to intensity of protein exchange. Fluctuations of biochemical indicators of blood were in limits of physiological norm, and, so introduction to a diet of these quantities of beer dry pellet had no negative impact for animals health. Feeding of the compound feed containing BDP reduces prime cost of 1 kg of gain in comparison with control by 2.6% in the 2nd experiment group and for 5.7% in the 3d experiment group. In 2nd and 3d groups, the level of profitability was 3.0-6.4 abs% higher than that in control respectively. Compound feeds cost for 2nd and 3d experiment groups was lower than the cost of compound feed of control group for 1.83% and 4.42% respectively. The experiments conducted give a chance to conclude that the use of BDP in compound feeds for young goat stocks has found to be profitable.

INFLUENCE OF STOCK HOUSE LIGHT ON DAIRY PRODUCTIVITY OF COWS

2020 ◽  
Keyword(s):  
Blood Serum ◽  
Physiological State ◽  
Light Level ◽  
Inorganic Phosphorus ◽  
Control Group ◽  
Hemoglobin Content ◽  
Milk Productivity ◽  
Reproductive Ability ◽  
The Cost ◽  
Experimental Group

The article is devoted to the solution of an urgent problem- influence of different lighting modes on the dairy productivity of cows. 2 groups of cows with 20 heads each were formed. In control group, light in the cowshed was 50-75 Lux for a light period of 7.5 h in January to 16.5 h in June, and in experimental group - 150-200 Lux and 16 h, respectively. It was found that the intensity and duration of illumination affects physiological state, reproductive ability and milk productivity of cows. In the experimental group of cows, compared with the control group, hemoglobin content in blood increased by 4.6% (P < 0.01), red blood cells - by 20.6% (P < 0.05), total protein - by 11.2% (P < 0.001), glucose - by 39.1% (P < 0.05). There was a tendency to increase the total calcium and inorganic phosphorus in blood serum of cows of the experimental group. The level of alkaline phosphatase in blood serum of cows in the control group was 71.5% (P < 0.01) higher than that of cows in the experimental group. Milk yield per 1 cow in the experimental cowshed was 433 kg more than in the control. The cost of 1 kg of milk in the experimental group was 0.94 rubles lower, and the profitability of milk production and sales is 9.42% higher than in the control group. To increase the milk productivity of cows, it is recommended to increase light level in barns for tethered keeping to 150-200 Lux, with the duration of lighting in the winter and transition periods of year up to 16 hours per day.

scholarly journals Prognostic Assessment of the Inflammatory Process Activity in Sarcoidosis of Respiratory Organs: Potential Use of C-reactive Protein and TNF-α

2017 ◽  
Vol 23 (2) ◽  
Author(s):  
Mykola Ostrovskyy ◽  
Kostiantyn Shvets
Keyword(s):  
Bronchoalveolar Lavage ◽  
Blood Serum ◽  
Peripheral Blood ◽  
Inflammatory Process ◽  
Bronchoalveolar Lavage Fluid ◽  
Research Work ◽  
Lavage Fluid ◽  
Control Group ◽  
Tnf Α ◽  
Α Level

This research work is devoted to the development of new additional criteria for the activity of inflammatory process in sarcoidosis of respiratory organs. The objective is to assess the effectiveness of performed treatment of sarcoidosis of respiratory organs by using low-cost highly-sensitive inflammatory markers.Materials and methods. The study involved 68 patients with lung sarcoidosis before and after the three-month treatment. In addition to general-clinical methods of examination, patients with sarcoidosis were also determined the levels of TNF-α and СRP.Results and their discussion. Patients with active lung sarcoidosis had 17.6 times (p<0.05) increased level of CRP in bronchoalveolar lavage fluid and 9.0 times (p<0.05) increased levels in peripheral blood serum; the levels of TNF-α increased by 4.98 times (p<0.05) in bronchoalveolar lavage fluid and by 3.2 times (p<0.05) in peripheral blood serum as compared to the findings in the control group of patients. The study showed that in the group of patients, where the efficacy of the prescribed therapy was noted, the level of CRP decreased by 2.76 times (p<0.05) in bronchoalveolar lavage fluid and by 2.58 times (p<0.05) in peripheral blood serum, and the concentration of TNF-α decreased by 3.87 times (p<0.05) in bronchoalveolar lavage fluid and by 2.06 times in peripheral blood serum as compared to the initial indices.Conclusions. The decrease of TNF-α level in bronchoalveolar lavage fluid on the background of three-months treatment correlated (r=0.89; p<0.05) to the changes in peripheral blood serum; at the same time the decrease of TNF-α level in peripheral blood serum correlated (r=0.82; p<0.05) to the decrease of CRP in peripheral blood serum of patients with sarcoidosis of respiratory organs. 

scholarly journals Diagnostic Criteria for Acute Destructive Pancreatitis

2021 ◽  
Vol 6 (2) ◽  
pp. 94-100
Author(s):  
V. M. Likhman ◽  
◽  
A. A. Merkulov ◽  
A. N. Shevchenko ◽  
S. V. Tkach ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Blood Serum ◽  
Acute Phase ◽  
Inflammatory Process ◽  
Acute Phase Proteins ◽  
Proteolytic Enzymes ◽  
The Body ◽  
Control Group ◽  
Antibacterial Prophylaxis ◽  
Surgical Methods

The relevance of the emergence of innovative technologies, more sophisticated diagnostics methods, opportunities for intensive therapy, antibacterial prophylaxis, surgical methods of treatment involving minimally invasive surgery, does not solve the problem of high overall mortality in severe acute pancreatitis at this time. This indicator for the last ten years remains at a high level (10-30%), and in case of inflammatory forms of severe pancreatitis, reaches 85%. Traditional laboratory criteria for the diagnosis of pancreatic necrosis may involve leukocytosis with the destruction of the leukocyte formula and appearance of myelocytes and metamylocytes in it; improvement of leukocyte index of intoxication; improvement of the nuclear index of the destruction; blood glucose growth; growth of blood urea; growth of neutrophil-lymphocytic coefficient; change in endogenous creatinine clearance; improvement of blood transaminases. The indicator enzymes have the greatest value for the diagnosis of gastrointestinal pancreatitis in the diagnostic plan. The determining of α-amylase activity is a sensitive and valuable criterion for diagnostics of gastrointestinal pancreatitis and control over the effectiveness of treatment. Also, talking about laboratory diagnostics of acute pancreatitis it is worth noting about acute-phase proteins. The increase in the level of acute-phase proteins in inflammation is a compensatory reaction associated with the ability to inhibit cells released during destruction and cause secondary tissue damage by proteolytic enzymes, as well as to suppress autoimmune aggression. Due to this, the inflammatory process in the body is limited and autoaggression is restrained. The purpose of the study was to study the proteins of the acute phase in the blood of patients with acute pancreatitis of varying severity. Materials and methods. The study is based on the results of examination of 88 patients with acute pancreatitis of varying severity who were treated at the V.T. Zaytsev Institute of the General and Urgent Surgery of Academy of Medical Sciences of Ukraine, Kharkiv, as well as 45 donors (control group). Results and discussion. The determination of the activity of serum enzymes in the dynamics of acute destructive pancreatitis was carried out. The parameters were verified before the operation and after the operative treatment in dynamics, as well as before and after the second operation in the dynamics. Markers of tissue destruction can simultaneously serve as indicators of the severity of the inflammatory process in the pancreas and determine the quality of the performed surgical intervention. The diagnostic value of ferritin and lactofferin as markers of an acute destructive process was proved on the basis of a significant increase in their level in blood serum and exudates of patients. It has been shown that ferroproteins are reliable markers of the inflammatory process, among others, including classical acute phase proteins. At the same time, their identification is distinguished by its explicitness in the diagnosis of not only latent destructive states. Conclusion. The detected changes in the concentration of clinical and laboratory parameters of alpha-2-macroglobulin, lactoferrin, C-reactive protein, ferritin in the blood serum correlate with the degree of the inflammatory process and purulent-destructive changes in the pancreas

scholarly journals THE LEVELS OF SOME CHEMOKINES IN THE BLOOD SERUM OF PATIENTS WITH EXACERBATION OF CHRONIC PURULENT RHINOSINUSITIS

2017 ◽  
pp. 30-33
Author(s):  
O. A. Nakonechnaya ◽  
A. I. Onischenko ◽  
T. V. Gorbach ◽  
A. S. Tkachenko ◽  
T. N. Chubukova
Keyword(s):  
T Lymphocytes ◽  
Blood Serum ◽  
Chronic Rhinosinusitis ◽  
Cytotoxic T Lymphocytes ◽  
Nasal Septum ◽  
Inflammatory Process ◽  
Control Group ◽  
Healthy Individuals ◽  
Septum Deviation ◽  
Nasal Septum Deviation

Aim: to study the levels of fractalkine and IL-8 in blood serum of patients with exacerbation of chronic purulent rhinosinusitis. Material and methods . Twenty patients suffering from chronic purulent rhinosinusitis were examined during the stage of exacerbation. The control group consisted of twenty conditionally healthy individuals with nasal septum deviation. The blood sampling of the examined patients was performed. The levels of fractalkine and IL-8 in the blood serum were determined by ELISA. Results. The exacerbation of purulent chronic rhinosinusitis leads to increased levels of both fractalkine and IL-8 in the blood serum of patients, which contributes to the involvement of neutrophils, monocytes, and cytotoxic T-lymphocytes into the inflammatory process. Chemokines IL-8 and fractalkine play an important role in the pathogenesis of chronic purulent rhinosinusitis, which suggests the reasonability of application of pharmacological preparations that block their functions. Conclusions. The carried out study revealed increased levels of both fractalkine and IL-8 in the blood serum of the patients with chronic purulent rhinosinusitis at the stage of exacerbation

scholarly journals Monocyte chemotactic factor content in normal sperm and in samples of ejaculate with diminished fertility

2019 ◽  
Vol 36 (3) ◽  
pp. 28-37
Author(s):  
Dmitriy Yu. Sosnin ◽  
Konstantin R. Galkovich
Keyword(s):  
Blood Serum ◽  
Seminal Plasma ◽  
Solid Phase ◽  
Reproductive Organs ◽  
Chemotactic Factor ◽  
Control Group ◽  
Mean Values ◽  
Healthy Men ◽  
Significant Difference ◽  
The Mean

Aim. To study the dynamics of monocyte chemotactic factor (MCP-1) content in the ejaculate of healthy men and men with diminished spermatozoid concentration. Material and methods.Sixty-four men were examined. The main group included 16 patients with azoospermia. The comparison group – 24 patients with oligozooasthenospermia (spermatozoid concentration lower than 15 mln/ml). The control group was presented by ejaculate samples of 24 healthy men, characterized by normal parameters. The MCP-1 concentration was determined with the method of solid phase enzyme immunoassay using the assay kit “MCP-1-EIA-BEST” (A8784) (CJSC Vector-Best, Russia). Results. The mean MCP-1 concentration in the samples of undiluted seminal plasma was 2242.8 ± 672.0 pg/ml versus the blood serum, where MCP-1 content was 18.9 times lower and was 118.8 ± 22.9 pg/ml. No reliable differences were revealed when comparing the mean values of MCP-1 in the studied groups in ejaculates; there were also no statistically significant difference between the indices in MCP-1 groups in the blood serum. Conclusions. Male seminal plasma is characterized by unusually high MCP-1 content, exceeding more than tenfold the concentration of this protein in the blood serum. High MCP-1 concentration in sperm and the absence of its dependence on the concentration of this protein in blood serum indicates local production of this protein into the seminal plasma by male reproductive organs. Further studies are needed to find out a concrete localization of the sites of production of this protein in male genital organs and to study its probable role in reproductive processes in male and female organisms.

scholarly journals ВПЛИВ ІНТРАВАСКУЛЯРНОГО ЛАЗЕРНОГО ОПРОМІНЕННЯ НА ПОКАЗНИКИ КРОВІ У КОРІВ ЗА ЛІКУВАННЯ ГНІЙНО-ЗАПАЛЬНИХ ПРОЦЕСІВ ДИСТАЛЬНОГО ВІДДІЛУ КІНЦІВОК

2014 ◽  
pp. 134-137
Author(s):  
І. І. Юрченко
Keyword(s):  
Alkaline Phosphatase ◽  
Blood Serum ◽  
Biochemical Parameters ◽  
Inflammatory Process ◽  
Control Group ◽  
Laboratory Results ◽  
Before And After ◽  
Inflammatory Processes ◽  
Hematological And Biochemical Parameters ◽  
Experimental Group

Висвітлені результати лабораторних дослідженькрові (сироватки) за низкою гематологічних і біохі-мічних показників від корів, хворих на гнійно-запальніпроцеси в дистальному відділі кінцівок, до та післявикористання інтраваскулярного лазерного опромі-нення крові. Встановлено, що використання ІЛОК ілокально порошку сульфату міді сприяє нормалізаціїзапального процесу. До того ж у сироватці крові ре-єструється вірогідне зниження активності аспара-гінової трансамінази та збільшення (в контрольнійгрупі) лужної фосфатази. Крім того у дослідній групівідмічали зниження, а в контрольній збільшення від-сотка лімфоцитів, а також збільшення гемоглобіну вдослідній та зменшення його в контролі. Laboratory results of blood (serum) for a range of hematological and biochemical parameters of cows sick on inflammatory processes in the distal extremities before and after use of intravascular laser irradiation of blood have been lit. It has been established that the use of locally ILOK and copper sulfate powder contributes to the normalization of the inflammatory process. In the blood serum is achieved a significant reduction of the activity of aspartic trans a minase and alkaline phosphatase is increased (in the control group).Also in the experimental group we saw a decreasing of the percentage of lymphocytes, and in control one - increasing the percentage of lymphocytes, as well as an increasing of hemoglobin in the experimental group and in control group – its reduction.

MYCOPLASMA AND CHLAMYDIA AS ETHIOLOGICAL FACTORS OF BRONCHIAL ASTHMA IN TERMS OF ETHNOGENESIS

2013 ◽  
Vol 68 (7) ◽  
pp. 57-60
Author(s):  
O. A. Sharavii ◽  
S. V. Smirnova
Keyword(s):  
Immune Response ◽  
Chlamydia Trachomatis ◽  
Blood Serum ◽  
Bronchial Asthma ◽  
Mycoplasma Hominis ◽  
Acute Stage ◽  
Control Group ◽  
Clinical Markers ◽  
Chlamydophila Psittaci ◽  
Asthma Patients

 Aim. The study of the prevalence and clinical peculiarities of Mycoplasmosis and Chlamydiosis in patients with different pathogenic forms of bronchial asthma (BA) taking into account ethnicity of a patient. Subjects and Methods. The research covered 239 subjects – both the Europeoids and the Mongoloids in the city of Krasnoyarsk and the town of Kyzyl, all of them being BA patients of different stages, including acute stage and practically healthy. We had determined antigens Mycoplasma pneumoniae, Mycoplasma hominis, Chlamydophila pneumoniae, Chlamydophila psittaci and Chlamydia trachomatis in smears of mucosa of pharynx and antibodies to these antigens in peripheral blood serum. Results.  We found high frequency of Mycoplasmosis and Chlamydiosis in the inhabitants of Eastern Siberia, BA patients with different pathogenic forms as compared to control group. We had determined ethnic peculiarities of specific immune response: IgM to М. pneumoniae was revealed in the Europoids more frequently than in the Mongoloids, but IgM to С. pneumoniae and to C. trachomatis, C. trachomatis antigens had been revealed more often in the Mongoloids than in the Europoids. We accepted as clinical equivalents of Mycoplasmosis and Chlamydiosis diagnostics the following signs: temperature around 37C (subfebrile temperature), non-intensive but stable coughing with scanty mucous and muco-purulent sputum, dyspnea of mixed character. Conclusions. Mycoplasma and Chlamydia are meaningful etiologic factors of bronchial asthma. We have found the peculiarities of immune response depending on ethnicity of a patient (ethnic belonging). Clinical markers of Mycoplasmosis and Chlamydiosis should be taken into account in bronchial asthma in order to provide diagnostics timely as well as eradication of infection agents. Because of insufficient knowledge of problem of bronchial asthma related to contamination with Мycoplasma and Chlamydia we put the goal to study the frequency of Mycoplasmosis and Chlamydiosis occurrence in bronchial asthma patients and determine the characteristics clinical course of diseases. We defined antigens Мycoplasma pneumoniae, Мycoplasma hominis, Chlamydophila pneumoniaе, Chlamydophila psittaci, Chlamydia trachomatis in smears of oropharynx mucosa and antibodies to them in blood serum. 

Determination of clinical efficiency of deproteinized dialysate from blood of milk-fed calves after endoprosthetics in patients with ventral hernias

2020 ◽  
Vol 28 (3) ◽  
pp. 323-333
Author(s):  
Sergej V. Ivanov ◽  
Ilya S. Ivanov ◽  
Evgenij G. Obyedkov ◽  
Liliya P. Popova
Keyword(s):  
Abdominal Wall ◽  
Inflammatory Reaction ◽  
Inflammatory Process ◽  
Anterior Abdominal Wall ◽  
Dynamic Change ◽  
Main Group ◽  
Control Group ◽  
Surgical Department ◽  
Regeneration Stage

Aim. To study the influence of deproteinized dialysate from blood of milk-fed calves on the type of exudative discharge and dynamics of inflammatory reaction after hernia repair with plastics of the anterior abdominal wall with hernioendoprosthesis of polypropylene. Materials and Methods. The study involved 59 patients being on stationary treatment in the surgical department of Kursk Regional Clinical Hospital. Patients were hospitalized for the herniation of small or medium dimension. The patients were divided to two groups: the main (n=30) and control (n=29) groups. After endoprosthetics, the patients of the control group were given complex conservative treatment. The patients of the main group, besides standard treatment, were administered deproteinized dialysate from blood of milk-fed calves intravenously in drips 10 ml + 200 ml of 0.9% sodium chloride solution within 7 days. For cytological examination and determination of the type of cytograms, the traumatic discharge was collected and analyzed using the method of M.F. Kamaev and M.A. Palthsev. Results. Cytomorphometric examination was conducted on the third, fifth and seventh day after endoprosthetics with the aim of studying dynamic changes. Determination of cell composition and also of its changes characteristic of each studied period, was necessary for obtaining further information characterizing inflammatory process in the region of placement of the endoprosthesis. After endoprosthetics in patients who were administered hemodialysate, the inflammatory reaction was less pronounced than in patients who did not receive the preparation. This was associated with a more dynamic change of stages of the inflammatory process. In patients of the main group who received deproteinized dialysate, regenerative type of inflammation first appeared on the fifth day and made 6.9%; by the seventh day the share of patients with the regenerative type rose to 17.5%, while in the patients of the control group no regeneration stage was observed in both periods. Conclusion. Analysis of the efficiency of influence of hemodialysate on the inflammatory reaction in plastics of the anterior abdominal wall with polypropylene endoprosthesis evidences faster course of all stages of inflammation and reduction of its intensity by 10%.

Sign in / Sign up

Export Citation Format

Share Document