The mexidol effects for activation of mitochondrial activity in athletes

2015 ◽  
Vol 9 (2) ◽  
pp. 0-0 ◽  
Author(s):  
Фудин ◽  
N. Fudin ◽  
Хадарцев ◽  
Aleksandr Khadartsev ◽  
Несмеянов ◽  
...  
Keyword(s):  
Body Weight ◽  
Comparative Study ◽  
Growth Performance ◽  
Human Body ◽  
Main Group ◽  
Mitochondrial Activity ◽  
Physiological Effects ◽  
Basic Properties ◽  
And Control

This brief report presents a description of the basic properties of mitochondria, providing a formation of energy in the human body, the ability to control a formation of energy under the influence of the Mexidol. The authors showed the main physiological effects of Mexidol in athletes and in various pathologies. A comparative study of growth performance of the pressing the barbell in the posture of lying and deadlifts in the main group of 15 people and control of 23 athletes was carried out. The athletes of the main group received the Mexidol in the dose of 200 mg/kg of body weight for 2,5 weeks. The authors found no significant increase of results in this group compared with the control and defined the importance of further studies of the properties of mitochondria and opportunities of the Mexidol in their modulation.

Effects of direct-fed microbial supplementation on growth performance and metabolic profile of newborn lambs weaned at different ages

2019 ◽  
Author(s):  
Ibrahim A. Alhidary ◽  
Riyadh S. Aljumaah ◽  
Ramzi A. Amran ◽  
Mutassim M. Abdelrahman ◽  
Abdullah N. Alowaimer ◽  
...  
Keyword(s):  
Body Weight ◽  
Mortality Rate ◽  
Growth Performance ◽  
Metabolic Profile ◽  
Body Weight Gain ◽  
Serum Triglyceride ◽  
Serum Zinc ◽  
Serum Cortisol ◽  
Final Body Weight ◽  
And Control

The aim of this study was to investigate the effects of direct fed microbial (DFM) supplementation on growth performance, metabolic profile and mortality rate of newborn lambs at different weaning ages. Five days old sixty Najdi male lambs (5.40 ± 0.10 kg BW) were randomly assigned to 1 of 4 treatments (15 lambs each): lambs received either no DFM and weaned at 60 days of age (control) or oral dose of DFM (5 ml) at 5, 10 and 15 days old, and weaned at 30 (DFM30), 45 (DFM45) or 60 (DFM60) days old, respectively. Final body weight was higher (P=0.05) and tended to be higher (P=0.09) in DFM30 and DFM45 lambs, respectively whereas body weight gain was higher (P=0.01) in DFM45 and DFM60 lambs. The mortality rate was declined from 33.3s% to 6.67% in DFM30 and DFM45 lambs compared to control ones. Serum cortisol and creatinine levels tended to be reduced (P=0.07 and 0.11, respectively) in DFM30 and DFM45 lambs. The serum total cholesterol was highest (P=0.02) in DFM60 lambs and lowest in both DFM45 and control lambs. Similarly, the DFM30 and DFM45 lambs showed a declined serum triglyceride compared with control and DFM60 lambs (P=0.02). Serum phosphorus declined (P=0.04) in DFM30 treated lambs while serum zinc and copper levels decreased (P=0.02 and 0.05, respectively) in all treatments compared to control lambs. These results indicated that DFM supplementation may enhance the growth and health of early weaned lambs.

scholarly journals Immunological female role tested on artificial plugs in three scorpion species

2018 ◽  
Author(s):  
Mariela A. Oviedo-Diego ◽  
Camilo I. Mattoni ◽  
Alfredo V. Peretti
Keyword(s):  
Body Weight ◽  
Comparative Study ◽  
Genital Atrium ◽  
The Body ◽  
Specific Response ◽  
Physiological Effects ◽  
Immunological Parameters ◽  
Genital Aperture ◽  
Interspecific Differences ◽  
Female Genital

AbstractWithin arachnids, genital plugs are morphologically diverse, and they can be formed by male, female or be a contribution of both sexes. Although several species of scorpions with genital plugs are known, the physiological effects on the female after being plugged have not been well studied yet. This work compares three scorpion species, two with genital plugs and one without. We first describe the genital plugs morphology of twoUrophoniusspecies. Second, through the placement of artificial genital plugs in the female genital atrium, we tested 1) whether there are interspecific differences in the immune encapsulation response on the artificial genital plug, 2) if there are an effect in the hemocyte load in the hemolymph, and 3) if individual’s immunological parameters and body weight are correlated. Additionally, we describe and quantify the hemocytes in these species. In both species ofUrophonius, genital plugs were found covering the female genital aperture and blocking the genital atrium. The plugs consist of three zones that are distinct in morphology and coloration. We found different patterns of encapsulation and melanization on the artificial plug according to the species, with a greater and more specific response in females of plug producing species. Also, these species showed a decrease in the hemocyte load one month after the placement of the artificial plug, possibly due to the recirculation of the hemocytes into the genital area. In addition, correlations were found between the body weight and the immunological parameters, as well as between different immunological parameters. Our results suggest that females contribute to the formation of genital plugs by adding material and generating the darkening of the genital plugs in certain zones. This comparative study can help to provide a wider framework of different physiological consequences related to a particular postcopulatory mechanism such as the genital plugs.

scholarly journals Supplementation of organic acid blends in water improves growth, meat yield, dressing parameters and bone development of broilers

2016 ◽  
Vol 45 (1) ◽  
pp. 7-18 ◽  
Author(s):  
ME Hossain ◽  
F Nargis
Keyword(s):  
Body Weight ◽  
Organic Acid ◽  
Growth Performance ◽  
Bone Development ◽  
The Other ◽  
Control Groups ◽  
Continuous Administration ◽  
Meat Yield ◽  
Periodic Administration ◽  
And Control

The present study was conducted in order to examine the effects of supplementing two liquid organic acid blends on growth performance, meat yield, dressing parameters, organ weights and bone development of broilers. A total of 120 broiler chicks were assigned to five dietary treatments in four replications with six birds per replication over a period of 5 weeks, following a completely randomized design. Dietary groups included; Control = Without organic acids; AW-C = Activate continuous administration; AW-P = Activate periodic administration; N-C = Nutrilac continuous administration; N-P = Nutrilac periodic administration. Results indicated that supplementation of organic acids improved (P<0.05) growth performance of broilers compared to the control. Among the supplemented groups, highest (P<0.05) body weight and body weight gain were in the AW-C group, followed by the N-C, AW-P, and N-P groups. Feed intake was higher (P<0.05) in the AW-C and N-C groups compared to the N-P and control groups. Feed conversion ratio was improved (P<0.05) in the organic acid groups, and the AW-C group showed the best value. Dressing yield as well as thigh and drumstick meat relative weights were higher (P<0.05) in the organic acid groups compared to control, whereas breast meat increased (P<0.05) in the AW-C group compared to the AW-P and control groups. Increased (P<0.05) relative weights of head and neck were observed in the AW-C group as well as that of gizzard in the N-C group compared to the other groups. On the other hand, abdominal fat content decreased (P<0.05) in the organic acid groups. Whole leg and wing bone relative weights increased (P<0.05) in the AW-C, AW-P, and N-C groups compared to the other groups. Further, longer (P<0.05) shank in the organic acid groups as well as longer drumstick bone length in the AW-C group were observed compared to the other groups. It was concluded based on the study results that supplementation of both organic acid blends improves growth performance, increases meat yield, organ development, dressing parameters and influences bone development of broilers. Therefore, as continuous addition of Activate showed better results compared to Nutrilac in terms of some tested parameters, it could be applied to broiler water to exert beneficial effects.Bang. J. Anim. Sci. 2016. 45 (1): 7-18

Somatometric assessment of premature infants in the sensitive period of development

2021 ◽  
Vol 22 (3) ◽  
pp. 76-81
Author(s):  
N. Yu. Putina ◽  
◽  
P. G. Koinosov ◽  
T. V. Chiryatyeva ◽  
An. P. Koinosov ◽  
...  
Keyword(s):  
Body Weight ◽  
Premature Infants ◽  
Main Group ◽  
The Body ◽  
Sensitive Period ◽  
Control Group ◽  
Control Groups ◽  
Timely Manner ◽  
Growth Processes ◽  
And Control

Aim. To establish the features of somatometric maturity of premature infants in the sensitive period of development. Material and methods. The somatometric method of the study was used to examine 124 children aged 7 years, who were divided into control and main groups. The control group included boys and girls with a history of traditional gestation periods. Boys and girls of the main group had all the signs of anatomical and physiological prematurity. Somatometric studies were carried out according to the traditional method, which included measurements of the overall dimensions of the body. On the basis of somatometric indicators, the indices of proportionality and harmony of the physique were calculated. The body types of children were determined according to the recommendations of V. G. Nikolaev (2007). To perform calculations of individual components of body weight, the manual of E. G. Martirosov (2010). Results. Somatometric studies have established sexual and intergroup differences in the physique of children aged 7 years. The analysis of the obtained data revealed the following feature: the longitudinal, transverse and girth dimensions in children of the control group are characterized by a significantly high increase by the age of 7. In children of the main group, the value of somatometric indicators is significantly lower, which is reflected in the lower massiveness and strength of the body of children of this group. It can be assumed that somatometric measurements revealed the features of growth processes in the physical development of children of the main and control groups. Somatometric studies can serve as objective criteria for the physical health of children and allow a more differentiated approach to the assessment of growth processes, as well as to predict possible deviations in a timely manner. Our study showed that the component composition of body weight has a significant impact on the formation of somatotypological features that reflect the degree of reactivity and resistance of the body of children at certain stages of development. The magnitude of endomorphy, mesomorphy and ectomorphy is characterized by sexual and intergroup differences that have a significant impact on the body shape and strength of the physique. Conclusion. Somatometric studies of the body of children aged 7 years allowed us to establish the features of growth processes in children of the main and control groups, which represent the norm of a biological reaction aimed at the optimal development of the child’s body. The revealed features in the morphofunctional status of children have established the mechanisms of compensatory and adaptive reactions that contribute to the formation of a certain morphotype. The structural and functional specificity of children is determined, which provides a certain reactivity and resistance of the body at the age of 7 years. Somatometric differences in the physical status of children are an objective criterion for the sanitary and hygienic well-being of the younger generation, and the data obtained allow us to identify deviations in a timely manner and carry out corrective measures.

Thromboembolic complications prevention in the obstetric practice

2017 ◽  
pp. 19-24
Author(s):  
O.V. Grishchenko ◽  
◽  
V.V. Bobrytska ◽  
Keyword(s):  
Pulmonary Embolism ◽  
Comparison Group ◽  
Main Group ◽  
Control Group ◽  
Efficacy And Safety ◽  
Thromboembolic Complications ◽  
Moderate Risk ◽  
Obstetric Practice ◽  
Thrombotic Complications ◽  
And Control

The objective: To evaluate the clinical efficacy and safety of Enoxaparin-Pharmex for the prevention of thrombotic complications (pulmonary embolism) in the postoperative period in patients with moderate risk of these complications. Patients and methods. The study included 50 women after a caesarean section had an average degree of risk of pulmonary embolism. Patients were divided into the main group (n=25) and control group (n=25) in accordance with the treatment: patients of the main group received postoperative Еnoxaparin- Pharmex, group comparisons enoxaparin sodium (brand foreign manufacturer’s). Patients in both groups received the drug at a dose of 20 mg for 5 days, 1 time per day subcutaneously. Results. The research data analysis showed identity results of hemostasiogram of patients in the main group and the comparison group, no side effects after treatment in both groups. Conclusion. The clinical studies suggest the drug Enoxaparin-Pharmex is effective, safe LMWH, which can be used to prevent troboembolic complications, including post-operative treatment in obstetric practice. Spectrum of Enoxaparin-Pharmex can be extended to the prevention and treatment of thromboembolic conditions of varying severity with appropriate doses of the drug. Key words: Enoxaparin-Pharmex, prevention of pulmonary embolism.

Representation of a Human Body: A Comparison Study between Balinese and Javanese Traditional House

Humaniora ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 83-90
Author(s):  
Anak Agung Ayu Wulandari ◽  
Ade Ariyani Sari Fajarwati
Keyword(s):  
Comparative Study ◽  
Human Body ◽  
Qualitative Method ◽  
Descriptive Analysis ◽  
The Body ◽  
Comparison Study ◽  
Architectural Drawing ◽  
Study Approach ◽  
The Comparative Study ◽  
Head Area

The research would look further at the representation of the human body in both Balinese and Javanese traditional houses and compared the function and meaning of each part. To achieve the research aim, which was to evaluate and compare the representation of the human body in Javanese and Balinese traditional houses, a qualitative method through literature and descriptive analysis study was conducted. A comparative study approach would be used with an in-depth comparative study. It would revealed not only the similarities but also the differences between both subjects. The research shows that both traditional houses represent the human body in their way. From the architectural drawing top to bottom, both houses show the same structure that is identical to the human body; head at the top, followed by the body, and feet at the bottom. However, the comparative study shows that each area represents a different meaning. The circulation of the house is also different, while the Balinese house is started with feet and continued to body and head area. Simultaneously, the Javanese house is started with the head, then continued to body, and feet area.

Extremes of Temperature

2017 ◽  
Author(s):  
Ann M. Krake
Keyword(s):  
Control Measures ◽  
Temperature Extremes ◽  
Physiological Effects ◽  
Assessment And Evaluation ◽  
The Public ◽  
Adverse Health Effects ◽  
Extreme Cold ◽  
Prevention And Control Measures ◽  
And Control ◽  
Extremes Of Temperature

This chapter covers extremes of temperature conditions, physiological effects, and prevention. All deaths caused by exposure to hot and cold temperature extremes are preventable when proper measures are taken. Described in this chapter are the effects of extreme heat and extreme cold on the health of members of the public, particularly older people and young people, and workers employed in various workplace settings. The differences between heat stress and heat strain are also discussed, as are various regulations governing exposure to temperature extremes. The nature and magnitude of heat- and cold-related conditions and symptoms are described in detail. Final sections of the chapter address various assessment and evaluation tools as well as prevention and control measures. In addition, an appendix describes the hazards related to hyperbaric and hypobaric environments and adverse health effects.

PSVI-16 The Association of Benzoic Acid and Essential Oils Eo Reduces the Inflammatory Response of Weaned Piglets and the Diarrhea Incidence in the Nursery Phase

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 202-203
Author(s):  
Sudario Roberto Silva Junior ◽  
Maíra Resende ◽  
Rhuan F Chaves ◽  
Jéssica Aparecida Barbosa ◽  
Iana I M Ferreira ◽  
...  
Keyword(s):  
Body Weight ◽  
Inflammatory Response ◽  
Benzoic Acid ◽  
Essential Oils ◽  
Growth Performance ◽  
Block Design ◽  
Basal Diet ◽  
Weaned Piglets ◽  
Total Period ◽  
Diarrhea Incidence

Abstract Benzoic acid (BA) and essential oils (EO) can minimize growth performance losses due to the removal of antibiotics and change the intestinal health of weaned piglets. The objective of this study was to evaluate the effects of BA and EO on inflammatory response, diarrhea incidence, and growth performance of the nursery phase. One hundred and twenty barrows were weaned at 23 days (6.40 ± 0.53 kg) and assigned into 3 treatments (10 replicates) in randomized block design: basal diet without additives (NC), basal diet with 200 ppm of colistin sulphate (PC), and association of 0,3% benzoic acid and essential oil (BA+EO). The feed intake and body weight were recorded at 0 and 42 days. The feces were assessed daily (per animal) and graded as normal feces (no diarrhea) or liquid or pasty stools (presence of diarrhea). On days 1, 3, and 9, blood samples were collected (5 replicates) for white blood cells (WBC) counts. Growth performance was analyzed by MIXED procedure (SAS, 2009) and the Tukey test was used to compare the means (P &lt; 0.050). The WBC counts were analyzed by repeated-measures analysis of variance, by MIXED procedure. Diarrhea incidence was analyzed by GENMOD procedure (SAS, 2009). The BA+EO treatment showed a similar body weight (P = 0.014) and average daily gain (P = 0.012) than the PC group and lower feed conversion ratio (P = 0.037) compared to the NC group. The pigs of the BA+EO treatment had the lowest diarrhea incidence during the total period (P &lt; 0.001). The supplementation with BA+EO or antibiotics reduced the counts of total WBC (P = 0.008) and neutrophils (P = 0.003). In conclusion, supplementation with BA+EO reduces the inflammatory response and the incidence of diarrhea in the nursery phase, that may be related to the improvement in the FCR.

Impact of an Infant Formula Containing a Novel Fat Blend (Cow’s Milk Fat, Fish and Vegetable Oil) and Prebiotics on Stool Fatty Acid Soaps and Erythrocyte Fatty Acid Profiles in Full-Term Healthy Newborns

2021 ◽  
pp. 1-8
Author(s):  
Maroula Lambidou ◽  
Birgit Alteheld ◽  
Rolf Fimmers ◽  
Frank Jochum ◽  
Antonia Nomayo ◽  
...  
Keyword(s):  
Body Weight ◽  
Fatty Acid ◽  
Infant Formula ◽  
Milk Fat ◽  
Control Group ◽  
Human Breast Milk ◽  
Infant Formulas ◽  
Fa Composition ◽  
And Control ◽  
Breast Fed

<b><i>Introduction:</i></b> Recently, new commercial infant formulas have been composed considering novel fat blends and oligosaccharides to better resemble the fatty acid (FA) composition and stereospecific distribution (e.g., increased amount of ß-palmitate) as well as probiotics content of human breast milk. We hypothesized that these newly composed infant formulas may decrease fecal FA soap excretion and may positively affect erythrocyte FA profiles compared with regular formulas. <b><i>Methods:</i></b> Healthy infants were randomly assigned to receive a high-sn-2-palmitate formula (&#x3e;25% of the PA is esterified to the sn-2 position of the glycerol backbone, verum: <i>n</i> = 30) or a “standard” formula containing &#x3c;10% of PA in sn-2 position and no oligosaccharides (control: <i>n</i> = 27); a non-randomized group of breast-fed infants served as control. Anthropometric data of the infants (body weight, recumbent length, and head circumference) were recorded at inclusion (visit 1) and 6 and 12 weeks after onset of intervention (visits 2 and 3). Blood samples for erythrocyte FA analysis (gas chromatography) were taken at visits 1 and 2; stool samples were collected at visit 2. <b><i>Results:</i></b> Quantitative formula intake (mL/kg body weight × day) at visit 2 (verum: 155 ± 30, control: 164 ± 30) and visit 3 (verum: 134 ± 26, control: 134 ± 21) was comparable. Six weeks after onset of intervention, stool total FA soaps, palmitate soaps, and total FAs were similar in both formula-fed groups but significantly higher than in breast-fed infants. During the 6-week intervention, erythrocyte palmitate decreased significantly from baseline in all 3 groups with no group differences (verum: 29.20 ± 1.17 to 27.12 ± 0.66, control: 29.88 ± 2.00 to 27.01 ± 0.94, breast-fed: 30.20 ± 0.86 to 26.84 ± 0.98). For selected FAs, significant changes over time in verum and control group were obvious but without formula effects. Some variations in the FA profile of breast-fed infants compared to both verum and control groups were observed. <b><i>Conclusions:</i></b> In contrast to our hypothesis, feeding a newly composed infant formula based on a fat blend with 25% of PA in the sn-2 position of triacylglycerols and supplemented with a prebiotic could not decrease insoluble FA soap excretion compared with a standard product; in this respect, breastfeeding is obviously the best choice. Surprisingly, erythrocyte FA profiles were comparable in formula-fed and breast-fed infants; obvious alterations in FA composition of the respective fat sources and structure did not affect FA incorporation into membranes. Caution should be, however, exercised in drawing robust conclusions in the absence of larger, adequately powered intervention studies.

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