scholarly journals Physicochemical properties of amino acid sequences of G-proteins for understanding GPCR-G-protein coupling

2006 ◽  
Vol 6 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Ganga D. Ghimire ◽  
Kenichiro Imai ◽  
Fumitsugu Akazawa ◽  
Toshiyuki Tsuji ◽  
Masashi Sonoyama ◽  
...  
Keyword(s):  
Amino Acid ◽  
Physicochemical Properties ◽  
G Protein ◽  
G Proteins ◽  
Amino Acid Sequences ◽  
G Protein Coupling ◽  
Protein Coupling

scholarly journals Physicochemical properties of GPCR amino acid sequences for understanding GPCR-G-protein coupling

2008 ◽  
Vol 8 (2) ◽  
pp. 49-57 ◽  
Author(s):  
Ganga D. Ghimire ◽  
Hideki Tanizawa ◽  
Masashi Sonoyama ◽  
Shigeki Mitaku
Keyword(s):  
Amino Acid ◽  
Physicochemical Properties ◽  
G Protein ◽  
Amino Acid Sequences ◽  
G Protein Coupling ◽  
Protein Coupling

scholarly journals Coupling of D2 dopamine receptors to G-proteins in solubilized preparations of bovine caudate nucleus

1992 ◽  
Vol 281 (2) ◽  
pp. 369-375 ◽  
Author(s):  
J A Chazot ◽  
P G Strange
Keyword(s):  
Ionic Strength ◽  
Caudate Nucleus ◽  
Dopamine Receptors ◽  
G Protein ◽  
G Proteins ◽  
Gel Filtration ◽  
D2 Dopamine Receptors ◽  
G Protein Coupling ◽  
Protein Coupling ◽  
Primary Determinant

1. The coupling of D2 dopamine receptors and G-proteins has been examined in cholate-solubilized preparations of bovine caudate nucleus. 2. No receptor-G-protein coupling could be detected in solubilized preparations obtained in 0.3% cholate, but if this preparation is diluted 5-fold, coupling is re-established. 3. The dilution process was examined, and it was shown that the change in ionic strength was an important factor in modulating the observed receptor-G-protein interaction. 4. Ionic strength was shown, however, not to be the primary determinant of receptor-G-protein coupling. This is likely to be the formation, upon dilution of the preparation, of vesicles in which receptor and G-protein reassociate. 5. The formation of vesicles upon dilution was examined by a variety of techniques, including thermal-stability studies, gel filtration, centrifugation and electron microscopy.

scholarly journals Amino acid residues in third intracellular loop of melanocortin 1 receptor are involved in G-protein coupling

IUBMB Life ◽  
1998 ◽  
Vol 46 (5) ◽  
pp. 913-922
Author(s):  
Per-Anders Frändberg ◽  
Marina Doufexis ◽  
Supriya Kapas ◽  
Vijay Chhajlani
Keyword(s):  
Amino Acid ◽  
G Protein ◽  
Amino Acid Residues ◽  
Intracellular Loop ◽  
G Protein Coupling ◽  
Melanocortin 1 Receptor ◽  
Protein Coupling ◽  
Third Intracellular Loop

The G-protein coupling properties of the human sweet and amino acid taste receptors

2007 ◽  
Vol 67 (7) ◽  
pp. 948-959 ◽  
Author(s):  
Eduardo Sainz ◽  
Margaret M. Cavenagh ◽  
Nelson D. LopezJimenez ◽  
Joanne C. Gutierrez ◽  
James F. Battey ◽  
...  
Keyword(s):  
Amino Acid ◽  
G Protein ◽  
Taste Receptors ◽  
G Protein Coupling ◽  
Protein Coupling

scholarly journals Amino Acid Side Chains That Define Muscarinic Receptor/G-protein Coupling

1996 ◽  
Vol 271 (6) ◽  
pp. 2882-2885 ◽  
Author(s):  
Ethan S. Burstein ◽  
Tracy A. Spalding ◽  
Mark R. Brann
Keyword(s):  
Amino Acid ◽  
G Protein ◽  
Muscarinic Receptor ◽  
Side Chains ◽  
G Protein Coupling ◽  
Protein Coupling ◽  
Amino Acid Side Chains
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