scholarly journals Proton-pump inhibitor increase small intestinal Inflammation

2014 ◽  
Vol 10 (2) ◽  
pp. 38-39
Author(s):  
Shunji Fujimori ◽  
Choitsu Sakamoto
Keyword(s):  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Intestinal Inflammation ◽  
Small Intestinal

W1238 Proton Pump Inhibitor (PPI) Lansoprazole Prevents Indomethacin-Induced Small Intestinal Ulceration in Rats: Involvement of Heme Oxygenase (HO)-1

2009 ◽  
Vol 136 (5) ◽  
pp. A-684 ◽  
Author(s):  
Yukiko Yoda ◽  
Kazuhide Higuchi ◽  
Koji Takeuchi ◽  
Eiji Umegaki ◽  
Satoshi Tokioka ◽  
...  
Keyword(s):  
Proton Pump Inhibitor ◽  
Heme Oxygenase ◽  
Proton Pump ◽  
Intestinal Ulceration ◽  
Small Intestinal

Proton-pump inhibitor therapy and small bowel bacterial contamination

2012 ◽  
Vol 153 (33) ◽  
pp. 1287-1293 ◽  
Author(s):  
József Hamvas
Keyword(s):  
Small Bowel ◽  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Breath Test ◽  
Bacterial Overgrowth ◽  
Small Intestinal Bacterial Overgrowth ◽  
Hydrogen Breath Test ◽  
Intestinal Bacterial Overgrowth ◽  
Small Intestinal

There are several causes of small bowel contamination. The effects of the long-term proton pump inhibitor treatment on the development of bowel symptoms and/or small intestinal bacterial overgrowth have been highlighted only in the past decade. The main diagnostic method is the hydrogen breath test that gives quantitative results with a simple, non-invasive procedure. There is a limited number of publications in the literature about the effects of proton pump inhibitor drugs on bowel bacterial milieau. Our results based on the investigations of two medical centres in Budapest show consistency with international data: the positive hydrogen breath test was present in 21% of the population using long-term proton pump inhibitors. In uncomplicated cases, symptom-free condition could be reached with probiotics, whereas in long lasting, chronic small intestinal bacterial overgrowth, antibiotic treatment should be considered. Rifaximin, a non-absorbable antibiotic showed high efficacy in the treatment of small intestinal bacterial overgrowth, with fewer side effects compared to systemic antibiotics. Orv. Hetil., 2012, 153, 1287–1293.

scholarly journals Proton Pump Inhibitor Therapy Use Does Not Predispose to Small Intestinal Bacterial Overgrowth

2011 ◽  
Vol 140 (5) ◽  
pp. S-806
Author(s):  
Shiva K. Ratuapli ◽  
Taylor G. Ellington ◽  
Mary O'Neill ◽  
Lucinda A. Harris ◽  
Amy E. Foxx-Orenstein ◽  
...  
Keyword(s):  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Bacterial Overgrowth ◽  
Small Intestinal Bacterial Overgrowth ◽  
Proton Pump Inhibitor Therapy ◽  
Inhibitor Therapy ◽  
Intestinal Bacterial Overgrowth ◽  
Small Intestinal
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