Characterization of NikA Histidine Kinase and Two Response Regulators with Special Reference to Osmotic Adaptation and Asexual Development inAspergillus nidulans

2009 ◽  
Vol 73 (7) ◽  
pp. 1566-1571 ◽  
Author(s):  
Daisuke HAGIWARA ◽  
Takeshi MIZUNO ◽  
Keietsu ABE
Keyword(s):  
Special Reference ◽  
Histidine Kinase ◽  
Asexual Development ◽  
Response Regulators ◽  
Osmotic Adaptation

scholarly journals Molecular Characterization of Two-Component Systems of Helicobacter pylori

2000 ◽  
Vol 182 (8) ◽  
pp. 2068-2076 ◽  
Author(s):  
Dagmar Beier ◽  
Rainer Frank
Keyword(s):  
Helicobacter Pylori ◽  
Histidine Kinase ◽  
Response Regulator ◽  
Response Regulators ◽  
Reading Frame ◽  
Component Systems ◽  
Two Component ◽  
Two Component Systems

ABSTRACT Two-component systems are frequently involved in the adaptation of bacteria to changing environmental conditions at the level of transcriptional regulation. Here we report the characterization of members of the two-component systems of the gastric pathogenHelicobacter pylori deduced from the genome sequence of strain 26695. We demonstrate that the response regulators HP166, HP1043, and HP1021 have essential functions, as disruption of the corresponding genes is lethal for the bacteria, irrespective of the fact that HP1043 and HP1021 have nonconserved substitutions in crucial amino acids of their receiver domains. An analysis of the in vitro phosphorylation properties of the two-component proteins demonstrates that HP244-HP703 and HP165-HP166 are cognate histidine kinase-response regulator pairs. Furthermore, we provide evidence that the variability of the histidine kinase HP165 caused by a poly(C) tract of variable length close to the 3′ end of open reading frame 165/164 does not interfere with the kinase activity of the transmitter domain of HP165.

scholarly journals Characterization of the NikA Histidine Kinase Implicated in the Phosphorelay Signal Transduction ofAspergillus nidulans, with Special Reference to Fungicide Responses

2007 ◽  
Vol 71 (3) ◽  
pp. 844-847 ◽  
Author(s):  
Daisuke HAGIWARA ◽  
Yoshihiro MATSUBAYASHI ◽  
Junichiro MARUI ◽  
Kentaro FURUKAWA ◽  
Takafumi YAMASHINO ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Special Reference ◽  
Histidine Kinase ◽  
Ofaspergillus Nidulans

Characterization of soluble, FSF-stabilized fibrin complexes with special reference to the role of fibrinogen

1974 ◽  
Vol 5 (1) ◽  
pp. 21-32 ◽  
Author(s):  
Bernt Ly ◽  
Peter Kierulf ◽  
Erling Jakobsen ◽  
Karl Gravem
Keyword(s):  
Special Reference ◽  
Stabilized Fibrin
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