29-Norcucurbitacin Derivatives Isolated from the Indonesian Medicinal Plant,Phaleria macrocarpa(Scheff.) Boerl.

2008 ◽  
Vol 72 (2) ◽  
pp. 618-620 ◽  
Author(s):  
Dikdik KURNIA ◽  
Kohki AKIYAMA ◽  
Hideo HAYASHI
Keyword(s):  
Medicinal Plant ◽  
Phaleria Macrocarpa

scholarly journals Pemulihan Kerusakan Jaringan Hati Mencit yang Diberi Ekstrak Butanol Buah Tua Mahkota Dewa

2018 ◽  
Vol 10 (1) ◽  
pp. 53
Author(s):  
Arif Soeksmanto
Keyword(s):  
Diabetes Mellitus ◽  
Body Weight ◽  
Medicinal Plant ◽  
Traditional Medicine ◽  
Tissue Damage ◽  
Liver Tissue ◽  
Butanol Extract ◽  
Phaleria Macrocarpa ◽  
Almost All

Mahkota dewa (Phaleria macrocarpa [Scheff.] Boerl.) is an Indonesians traditional medicinal plant used to treat various diseases, such as diabetes mellitus, hemorrhoid, impotency and cancer. Almost all parts of the plants canbe used as traditional medicine, but if directly consumed, it can cause swollen, sprue, numb at tongue, fever, even unconsciousness. This research was carried out to find out recovery of liver tissue damage of mice administered intraperitoneally with subchronic dosage of butanol extract 170 mg/kg body weight. Observation on first week showed that there is light degeneration (vacuolization) which is getting better on second week and apparentlynormal on forth week.

scholarly journals Uji Aktivitas Antimikroba Ekstrak Daun Mahkota Dewa (Phaleria macrocarpa) dengan Metode Difusi Cakram

2020 ◽  
Vol 6 (1) ◽  
pp. 8
Author(s):  
M. Fiqriansyah Wahab ◽  
Yustika Indahsari ◽  
Nurdiana Nurdiana ◽  
Andi Maghfira Manggabarani ◽  
Putri Bella Aulia Nur
Keyword(s):  
Staphylococcus Aureus ◽  
Medicinal Plant ◽  
Bacterial Growth ◽  
Leaf Extract ◽  
Inhibitory Zone ◽  
E Coli ◽  
Phaleria Macrocarpa ◽  
And Staphylococcus Aureus

Indonesia has abundant biological rich potential so it needs to be researched and utilized especially for various plants that have potential as medicine. One of the plants that can be used as a medicinal plant and has many benefits is the Phaleria macrocarpa. This study aimed to determine the effectiveness of P. macrocarpa leaf extract to inhibit the growth of Escherecia coli and Staphylococcus aureus bacteria. The results showed that the leaf extract of P. macrocarpa containing tannin compounds has the ability to inhibit bacterial growth. The extract of the crown of the deity of the god is more effective in inhibiting the growth of S. aureus bacteria compared to E. coli bacteria which is shown with a larger inhibitory zone. It means that the extract of the P. macrocarpa can be used as a medicinal ingredient for diseases caused by S. aureus bacteria

scholarly journals UJI EFEK ANALGESIK EKSTRAK DAUN MAHKOTA DEWA (Phaleria macrocarpa) PADA MENCIT (Mus musculus)

2014 ◽  
Vol 1 (2) ◽  
Author(s):  
Dinar Salsabila Tone ◽  
Christi Mambo
Keyword(s):  
Treatment Group ◽  
Medicinal Plant ◽  
Mus Musculus ◽  
Analgesic Effect ◽  
Positive Control ◽  
Negative Control ◽  
Control Group ◽  
Male And Female ◽  
Average Value ◽  
Phaleria Macrocarpa

ABSTRACTThe plant of Mahkota Dewa is a traditional plant which is used as a medicinal plant whose benefits are located in almost parts where it contains flavonoid and saponin compounds that have a variety of effects and one of them is analgesic effect. This research aims to determine the analgesic effect of the extract of Mahkota Dewa leaf (Phaleria macrocarpa) in mices (Mus musculus). This research uses an experimental method using nine male and female mices which are divided into three groups: the positive control group that was given aspirin and the negative control that was given aquades and the treatment group that was given the extract of the Mahkota Dewa leaf. The research is done by giving the stimulus of pain in the form of heat 55o.C and then observes the response of the tested animal such as jumping or licking its legs and at the minute of 0 before treatment, and at the minutes of 30, 60, 90, 120 after the treatment. The average value of the number of respons of mices which were given the extract of the Mahkota Dewa leaf decreases from the 30th minute until the 90th minute. Conclusion. The extract of Mahkota Dewa leaf has an analgesic effect in Mouse.Key Word: Analgesic, Aspirin, Mahkota Dewa leaf (Phaleria macrocarpa)ABSTRAKTanaman mahkota dewa merupakan tumbuhan tradisional yang digunakan sebagai tumbuhan obat yang manfaatnya terletak hampir di seluruh bagian dimana di dalamnya terkandung senyawa-senyawa flavonoid dan saponin yang mempunyai bermacam-macam efek dan salah satunya adalah efek analgesik. Penelitian ini bertujuan untuk mengetahui efek analgesik dari ekstrak daun mahkota dewa (Phaleria macrocarpa) pada mencit (Mus musculus). Penelitian ini menggunakan metode eksperimental dengan menggunakan 9 ekor mencit jantan dan betina yang dibagi atas 3 kelompok yaitu kelompok kontrol positif yang diberi obat aspirin, kontrol negatif yang diberi aquades dan kelompok perlakuan yang diberi ekstrak daun mahkota dewa. Penelitian dilakukan dengan cara memberi rangsangan nyeri berupa suhu panas 55o.C kemudian mengamati respon hewan uji berupa melompat dan atau menjilat kaki pada menit ke-0 sebelum perlakuan, dan pada menit ke-30, 60, 90, 120 setelah perlakuan. Nilai rata-rata jumlah respon mencit yang diberikan ekstrak daun mahkota dewa mengalami penurunan dari menit ke-30 sampai menit ke-90. Kesimpulan. Ekstrak daun mahkota dewa memiliki efek analgesik pada mencit.Kata kunci: Analgesik, Aspirin, Daun Mahkota Dewa (Phaleria macrocarpa)

Stereochemistry of Lignans in Phaleria macrocarpa (Scheff.) Boerl.

2008 ◽  
Vol 63 (1-2) ◽  
pp. 13-16 ◽  
Author(s):  
Ahmad Saufi ◽  
Cosima B. I. von Heimendahl ◽  
A. Wilhelm Alfermann ◽  
Elisabeth Fuss
Keyword(s):  
Medicinal Plant ◽  
Enantiomeric Excess ◽  
Enantiomeric Composition ◽  
Chiral Column ◽  
Phaleria Macrocarpa ◽  
Pure Enantiomer ◽  
Different Parts

Phaleria macrocarpa (Scheff.) Boerl., a member of the Thymelaeaceae, is traditionally used in Indonesia as medicinal plant against cancer. In this context, we isolated the lignans pinoresinol, lariciresinol and matairesinol from different parts of this plant. The enantiomeric composition of these lignans was determined by chiral column analysis. Pinoresinol and lariciresinol were mixtures of both enantiomers with (79 ± 4)% and (55 ± 6)% enantiomeric excess for the (−)-enantiomers, respectively, whereas matairesinol was found as pure (+)-enantiomer.

Triterpenoid saponins from the cytotoxic root extract of Sideroxylon foetidissimum, an endemic Yucatecan medicinal plant

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
A Sánchez-Medina ◽  
PC Stevenson ◽  
S Habtemariam ◽  
LM Peña-Rodríguez ◽  
O Corcoran ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Root Extract ◽  
Triterpenoid Saponins

Mexican copalchis (Rubiaceae): One hundred years of research of a medicinal plant complex

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
R Mata ◽  
J Guerrero ◽  
F Palacios ◽  
S Cristians ◽  
R Bye
Keyword(s):  
Medicinal Plant

Molecular authentication of Thai medicinal plant Khamin khruea by PCR-RFLP analysis

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
P Rojsanga ◽  
W Gritsanapan ◽  
W Leelamanit ◽  
S Sukrong
Keyword(s):  
Medicinal Plant ◽  
Rflp Analysis ◽  
Molecular Authentication ◽  
Pcr Rflp
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