Characterization of Apoptosis Induced by Fucoxanthin in Human Promyelocytic Leukemia Cells

2005 ◽  
Vol 69 (1) ◽  
pp. 224-227 ◽  
Author(s):  
Eiichi KOTAKE-NARA ◽  
Masaru TERASAKI ◽  
Akihiko NAGAO
Keyword(s):  
Promyelocytic Leukemia ◽  
Leukemia Cells

Isolation and characterization of thioguanine resistant human promyelocytic leukemia cells

1980 ◽  
Vol 4 (1) ◽  
pp. 151-154 ◽  
Author(s):  
A.J. Bodner ◽  
S. Tsai ◽  
R.C. Ting ◽  
S.J. Collins ◽  
R.C. Gallo
Keyword(s):  
Promyelocytic Leukemia ◽  
Leukemia Cells ◽  
Isolation And Characterization

Pharmacological characterization of the histamine uptake system in HL-60 human promyelocytic leukemia cells

1986 ◽  
Vol 6 (4) ◽  
pp. 403-407 ◽  
Author(s):  
Christian Gespach ◽  
Noel Marrec ◽  
Jean-Pierre Abita
Keyword(s):  
Peripheral Blood ◽  
Histamine Receptor ◽  
Promyelocytic Leukemia ◽  
Leukemia Cells ◽  
Uptake System ◽  
Active Process ◽  
Pharmacological Characterization ◽  
H2 Receptor ◽  
Histamine Uptake

Serotonin and histamine H1, H2 receptor agonists or antagonists inhibited [3H]histamine uptake by HL-60 cells, according to the following order of potency: impromidine >4-MH>histamine>AET>PEA and: cimetidine, histamine>diphenhydramine, serotonin. It is concluded that histamine uptake by HL-60 cells was specifically controlled by the H2 type histamine receptor and that this active process might be involved in pathophysiological regulations in leukemic and normal granulocytic precursors and in the control of histamine levels in peripheral blood and tissues in man.

scholarly journals Characterization of Human Alpha-Dystrobrevin Isoforms in HL-60 Human Promyelocytic Leukemia Cells Undergoing Granulocytic Differentiation

2002 ◽  
Vol 13 (12) ◽  
pp. 4195-4205 ◽  
Author(s):  
Agné Kulyte ◽  
Ruta Navakauskiene ◽  
Grazina Treigyte ◽  
Arunas Gineitis ◽  
Tomas Bergman ◽  
...  
Keyword(s):  
Myosin Light Chain ◽  
Biochemical Properties ◽  
Promyelocytic Leukemia ◽  
Leukemia Cells ◽  
Human Neutrophils ◽  
Phagocytic Cells ◽  
Granulocytic Differentiation ◽  
Splice Isoforms ◽  
New Information

The biochemical properties and spatial localization of the protein alpha-dystrobrevin and other isoforms were investigated in cells of the human promyelocytic leukemia line HL-60 granulocytic differentiation as induced by retinoic acid (RA). Alpha-dystrobrevin was detected both in the cytosol and the nuclei of these cells, and a short isoform (gamma-dystrobrevin) was modified by tyrosine phosphorylation soon after the onset of the RA-triggered differentiation. Varying patterns of distribution of alpha-dystrobrevin and its isoforms could be discerned in HL-60 promyelocytes, RA-differentiated mature granulocytes, and human neutrophils. Moreover, the gamma-dystrobrevin isoform was found in association with actin and myosin light chain. The results provide new information about potential involvement of alpha-dystrobrevin and its splice isoforms in signal transduction in myeloid cells during induction of granulocytic differentiation and/or at the commitment stage of differentiation or phagocytic cells.

Thymosin Fraction-5 Possesses Antiproliferative Properties in HL-60 Human Promyelocytic Leukemia Cells: Characterization of an Active Peptide

2007 ◽  
Vol 1112 (1) ◽  
pp. 305-316 ◽  
Author(s):  
B. L. SPANGELO ◽  
J. D. ROACH ◽  
F. HADI ◽  
A. A. DAMAVANDY ◽  
J. PLIESKATT ◽  
...  
Keyword(s):  
Promyelocytic Leukemia ◽  
Leukemia Cells ◽  
Active Peptide
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