Plasma Cholesterol-lowering Effect on Rats of Dietary Fiber Extracted from Immature Plants

2000 ◽  
Vol 64 (12) ◽  
pp. 2543-2551 ◽  
Author(s):  
Naomichi NISHIMURA ◽  
Yuji TANIGUCHI ◽  
Shuhachi KIRIYAMA
Keyword(s):  
Dietary Fiber ◽  
Plasma Cholesterol ◽  
Cholesterol Lowering ◽  
Lowering Effect ◽  
Cholesterol Lowering Effect

scholarly journals Cholesterol-lowering effect of soyabean lecithin in normolipidaemic rats by stimulation of biliary lipid secretion

1996 ◽  
Vol 75 (3) ◽  
pp. 471-481 ◽  
Author(s):  
Elisabeth Polichetti ◽  
Nicolas Diaconescu ◽  
Paulette Lechene De La Porte ◽  
Lina Malli ◽  
Henri Portugal ◽  
...  
Keyword(s):  
Plasma Cholesterol ◽  
Hdl Cholesterol ◽  
Biliary Lipid ◽  
Total Lipids ◽  
High Fat ◽  
Cholesterol Lowering ◽  
Lowering Effect ◽  
Low Fat Diet ◽  
Fat Diets ◽  
Cholesterol Lowering Effect

AbstractThe purpose of the present study was to assess the role of the liver in the plasma-cholesterol-lowering effect of soyabean lecithin. Normolipidaemic rats were fed on lecithin-enriched or control diets with the same amount of protein. The lecithin diets contained 200 g/kg high-fat commercial semi-purified soyabean lecithin (230 g/kg total lipids as soyabean phosphatidylcholine) or 200 g/kg high-fat purified soyabean lecithin (930 g/kg total lipids as soyabean phosphatidylcholine). The control diets were a low-fat diet (40 g fat/kg) and a high-fat triacylglycerol-rich diet (200 g fat/kg). The high-fat diets were isoenergetic. The cholesterol-lowering effect of the lecithin-enriched diets was associated with significantly lower levels of plasma total- and HDL-cholesterol and significantly higher levels of bile phosphatidylcholine (PC), bile salts and cholesterol. These findings suggest that the liver plays a major role in the reduction of plasma cholesterol, the increased biliary lipid being provided by both HDL and the hepatic microsomal pools of PC and cholesterol.

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