scholarly journals Effects of Chemical Modification of Carboxyl Groups in the Hemolytic Lectin CEL-III on Its Hemolytic and Carbohydrate-Binding Activities

2000 ◽  
Vol 64 (6) ◽  
pp. 1278-1281
Author(s):  
Hiromiki KUWAHARA ◽  
Takako FUNADA ◽  
Tomomitsu HATAKEYAMA ◽  
Haruhiko AOYAGI
Keyword(s):  
Chemical Modification ◽  
Carboxyl Groups ◽  
Carbohydrate Binding

Effect of Lectins and Chemical Modification on the Hemagglutinin Activity of Human Plasma Fibronectin

1981 ◽  
Vol 36 (9-10) ◽  
pp. 863-868 ◽  
Author(s):  
Matti Vuento ◽  
Eija Salonen
Keyword(s):  
Chemical Modification ◽  
Human Plasma ◽  
Present Report ◽  
Red Cells ◽  
Carboxyl Groups ◽  
Plasma Fibronectin ◽  
Cell Surfaces ◽  
Serum Factors ◽  
Low Concentrations ◽  
Erythrocyte Surface

Abstract Purified hum an plasm a fibronectin has been shown to agglutinate protease-treated red cells [Vuento, Hoppe-Seyler's Z. Physiol. Chem. 360, 1327-1333, (1979)]. The present report shows that the activity is inhibited by low concentrations of lectins and by macrom olecular serum factors. Chemical m odification of carboxyl groups of fibronectin strongly inhibited the activity, but modification of am ino groups or guanidinium groups had little effect on the activity. The results suggest that fibronectin receptors on erythrocyte surface are carbohydrate-containing molecules. Humoral m acrom olecular factors may control the interaction of fibronectin with cell surfaces. Chemical m odification studies indicate that the parts of the fibronectin molecule responsible for the hem agglutinin activity are different from those mediating the binding of fibronectin to collagen.

Chemical modification of carboxyl groups in human Fcγ fragment: Structural role and effect on the complement fixation

1980 ◽  
Vol 17 (3) ◽  
pp. 327-336 ◽  
Author(s):  
F. Vivanco-Martínez ◽  
R. Bragado ◽  
J.P. Albar ◽  
C. Juarez ◽  
F. Ortíz-Masllorens
Keyword(s):  
Chemical Modification ◽  
Complement Fixation ◽  
Carboxyl Groups ◽  
Structural Role

Study on a Photonic Crystal Hydrogel Material for Chemical Sensing

2015 ◽  
Vol 14 (01n02) ◽  
pp. 1460025
Author(s):  
Jia-Yu Xu ◽  
Chun-Xiao Yan ◽  
Xiao-Chun Hu ◽  
Chao Liu ◽  
Hua-Min Tang ◽  
...  
Keyword(s):  
Photonic Crystal ◽  
Ionic Strength ◽  
Chemical Modification ◽  
Chemical Sensing ◽  
Electrostatic Interactions ◽  
Carboxyl Groups ◽  
Polystyrene Spheres ◽  
Crystalline Colloidal Arrays ◽  
Crystalline Colloidal Array ◽  
Monodisperse Polystyrene

There is intense interest in the applications of photonic crystal hydrogel materials for the detection of glucose, metal ions, organophosphates and so on. In this paper, monodisperse polystyrene spheres with diameters between 100 ~ 440 nm were synthesized by emulsion polymerization. Highly charged polystyrene spheres readily self-assembled into crystalline colloidal array because of electrostatic interactions. Photonic crystal hydrogel materials were formed by polymerization of acrylamide hydrogel around the crystalline colloidal arrays of polystyrene spheres. After chemical modification of hydrogel backbone with carboxyl groups, our photonic crystals hydrogel materials are demonstrated to be excellent in response to pH and ionic strength changes.

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