scholarly journals The Increased Effect of Kneading on the Formation of Inclusion Complexes between d-Limonene and .BETA.-Cyclodextrin at Low Water Content.

1998 ◽  
Vol 62 (3) ◽  
pp. 464-468 ◽  
Author(s):  
Hidefumi YOSHII ◽  
Takeshi FURUTA ◽  
Eiji OKITA ◽  
Akira TOYOMI ◽  
Yu-Yen LINKO ◽  
...  
Keyword(s):  
Water Content ◽  
Inclusion Complexes ◽  
Beta Cyclodextrin

scholarly journals Host–Guest Inclusion Complexes of Essential Oils with Strong Antibacterial and Antifungal Features in Beta-Cyclodextrin for Solid-State Pharmaceutical Applications

2021 ◽  
Vol 11 (14) ◽  
pp. 6597
Author(s):  
Aldo Arrais ◽  
Marta Manzoni ◽  
Alessia Cattaneo ◽  
Valentina Gianotti ◽  
Nadia Massa ◽  
...  
Keyword(s):  
Solid State ◽  
Essential Oil ◽  
Essential Oils ◽  
Inclusion Complexes ◽  
Production Costs ◽  
Good Tolerance ◽  
Actual Application ◽  
Beta Cyclodextrin ◽  
Ft Ir ◽  
Antibacterial And Antifungal

Essential oils are widely recognized as natural alternatives to pharmaceutical antibacterial and antifungal agents. With respect to standard pharmaceutics, the advantages of essential oils are their (i) low production costs, (ii) lack of chemical and biochemical drawbacks that are intrinsic to the synthetic production process and (iii) good tolerance by humans. On the other hand, the liquid nature of essential oils poses concerns about their actual application in different therapeutic issues regarding their persistence and the ability to control or prolong drug release. In this study, two essential oils from oregano and winter savory showing antibacterial and antifungal features were complexed in a solid state with beta-cyclodextrin. Host–guest inclusion complexes were characterized using FT-IR spectroscopy, ESI-MS and GC-MS techniques. Manyfold terpenic and non-terpenic components of the oils could be observed and unambiguously identified as being included inside the carbohydrate hosts. Many of them provided a specific biocidal action. Indeed, essential oil host–guest inclusion products were tested against two Candida species and an S. aureus reference strain, showing that the oils effectively maintained their liquid performances. Solid-state tablets of the essential oil inclusion complexes embedded in polyvinylpyrrolidone could be obtained. These results pave the way for the solid-state application of essential oils in antibacterial and antifungal pharmaceutical treatments.

Stability, biological and biopharmaceutical evaluation of the inclusion complexes of the antifungal and antiprotozoal drug candidate 2-(2-nitrovinyl) furan (G-0) with beta cyclodextrin derivatives

2020 ◽  
Vol 58 ◽  
pp. 101767
Author(s):  
Vivian Ruz Sanjuan ◽  
Guy Van den Mooter ◽  
Iracilda Zeppone Carlos ◽  
Matheus Aparecido dos Santos Ramos ◽  
Taís Maria Bauab ◽  
...  
Keyword(s):  
Inclusion Complexes ◽  
Drug Candidate ◽  
Cyclodextrin Derivatives ◽  
Beta Cyclodextrin

Separation of drug stereoisomers by the formation of beta-cyclodextrin inclusion complexes

Science ◽  
1986 ◽  
Vol 232 (4754) ◽  
pp. 1132-1135 ◽  
Author(s):  
D. Armstrong ◽  
T. Ward ◽  
R. Armstrong ◽  
T. Beesley
Keyword(s):  
Inclusion Complexes ◽  
Cyclodextrin Inclusion Complexes ◽  
Beta Cyclodextrin ◽  
Cyclodextrin Inclusion
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