Loss of a GPI-Anchored Membrane Protein Aah3p Causes a Defect in Vacuolar Protein Sorting inSchizosaccharomyces pombe

2007 ◽  
Vol 71 (2) ◽  
pp. 623-626 ◽  
Author(s):  
Tomoko IWAKI ◽  
Tomotake MORITA ◽  
Naotaka TANAKA ◽  
Yuko GIGA-HAMA ◽  
Kaoru TAKEGAWA
Keyword(s):  
Membrane Protein ◽  
Protein Sorting ◽  
Vacuolar Protein Sorting ◽  
Vacuolar Protein

scholarly journals CONTINUOUS VASCULAR RING (COV1) is a trans-Golgi Network-Localized Membrane Protein Required for Golgi Morphology and Vacuolar Protein Sorting

2014 ◽  
Vol 55 (4) ◽  
pp. 764-772 ◽  
Author(s):  
Makoto Shirakawa ◽  
Haruko Ueda ◽  
Yasuko Koumoto ◽  
Kentaro Fuji ◽  
Chiaki Nishiyama ◽  
...  
Keyword(s):  
Membrane Protein ◽  
Protein Sorting ◽  
Vascular Ring ◽  
Vacuolar Protein Sorting ◽  
Trans Golgi Network ◽  
Vacuolar Protein ◽  
Golgi Network

scholarly journals An Interorganellar Bidding War: Vps13 Localization by Competitive Organelle-Specific Adaptors

Contact ◽  
2018 ◽  
Vol 1 ◽  
pp. 251525641881462
Author(s):  
Samantha K. Dziurdzik ◽  
Björn D.M. Bean ◽  
Elizabeth Conibear
Keyword(s):  
Endoplasmic Reticulum ◽  
Recent Work ◽  
Protein Sorting ◽  
Repeat Region ◽  
Vacuolar Protein Sorting ◽  
Membrane Contact Sites ◽  
Contact Sites ◽  
Prospore Membrane ◽  
Membrane Contact ◽  
Vacuolar Protein

Membrane contact sites are regulated through the controlled recruitment of constituent proteins. Yeast vacuolar protein sorting 13 (Vps13) dynamically localizes to membrane contact sites at endosomes, vacuoles, mitochondria, and the endoplasmic reticulum under different cellular conditions and is recruited to the prospore membrane during meiosis. Prior to our recent work, the mechanism for localization at contact sites was largely unknown. We identified Ypt35 as a novel Vps13 adaptor for endosomes and the nucleus-vacuole junction. Furthermore, we discovered a conserved recruitment motif in Ypt35 and found related motifs in the prospore membrane and mitochondrial adaptors, Spo71 and Mcp1, respectively. All three adaptors compete for binding to a six-repeat region of Vps13, suggesting adaptor competition regulates Vps13 localization. Here, we summarize and discuss the implications of our work, highlighting key outstanding questions.

MP005INCREASED LYSOSOMAL DEGRADATION OF AQP2 IN MPKCCDC14 CELLS WITH KNOCKDOWN OF VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i345-i345
Author(s):  
Hyo-Jung Choi ◽  
Mi Suk Lee ◽  
Dasom Kim ◽  
Eui-Jung Park ◽  
Yu-Jung Lee ◽  
...  
Keyword(s):  
Protein Sorting ◽  
Lysosomal Degradation ◽  
Vacuolar Protein Sorting ◽  
Vacuolar Protein

Vacuolar Protein Sorting in Yeast

1993 ◽  
pp. 329-338
Author(s):  
Bruce F. Horazdovsky ◽  
Todd R. Graham ◽  
Scott D. Emr
Keyword(s):  
Protein Sorting ◽  
Vacuolar Protein Sorting ◽  
Vacuolar Protein
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