Accelerated Alcoholic Fermentation Caused by Defective Gene Expression Related to Glucose Derepression inSaccharomyces cerevisiae

2013 ◽  
Vol 77 (11) ◽  
pp. 2255-2262 ◽  
Author(s):  
Daisuke WATANABE ◽  
Naoya HASHIMOTO ◽  
Megumi MIZUNO ◽  
Yan ZHOU ◽  
Takeshi AKAO ◽  
...  
Keyword(s):  
Gene Expression ◽  
Alcoholic Fermentation ◽  
Defective Gene

Defective gene expression of MnSOD in tumor cells

1993 ◽  
Vol 15 (5) ◽  
pp. 503
Author(s):  
T. Galeotti ◽  
S. Borrello ◽  
M.E. De Leo ◽  
G. Piccirillo ◽  
F. Ria ◽  
...  
Keyword(s):  
Gene Expression ◽  
Tumor Cells ◽  
Defective Gene

scholarly journals Synthetic long non-coding RNAs [SINEUPs] rescue defective gene expression in vivo

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Alessia Indrieri ◽  
Claudia Grimaldi ◽  
Silvia Zucchelli ◽  
Roberta Tammaro ◽  
Stefano Gustincich ◽  
...  
Keyword(s):  
Gene Expression ◽  
Defective Gene ◽  
Non Coding Rnas

scholarly journals GALpromoter-driven heterologous gene expression inSaccharomyces cerevisiaeΔ strain at anaerobic alcoholic fermentation

2013 ◽  
Vol 13 (1) ◽  
pp. 140-142 ◽  
Author(s):  
Jungoh Ahn ◽  
Kyung-Min Park ◽  
Hongweon Lee ◽  
Yeo-Jin Son ◽  
Eui-Sung Choi
Keyword(s):  
Gene Expression ◽  
Alcoholic Fermentation ◽  
Heterologous Gene Expression ◽  
Heterologous Gene

Genome-wide monitoring of wine yeast gene expression during alcoholic fermentation

Yeast ◽  
2003 ◽  
Vol 20 (16) ◽  
pp. 1369-1385 ◽  
Author(s):  
Tristan Rossignol ◽  
Laurent Dulau ◽  
Anne Julien ◽  
Bruno Blondin
Keyword(s):  
Gene Expression ◽  
Alcoholic Fermentation ◽  
Wine Yeast ◽  
Yeast Gene ◽  
Genome Wide

Defective gene expression of MnSOD in cancer cells

1993 ◽  
Vol 14 (3) ◽  
pp. 253-258 ◽  
Author(s):  
S. Borrello ◽  
M.E. De Leo ◽  
T. Galeotti
Keyword(s):  
Gene Expression ◽  
Cancer Cells ◽  
Defective Gene

scholarly journals Transcriptional Response of Saccharomyces cerevisiae to Different Nitrogen Concentrations during Alcoholic Fermentation

2007 ◽  
Vol 73 (9) ◽  
pp. 3049-3060 ◽  
Author(s):  
A. Mendes-Ferreira ◽  
M. del Olmo ◽  
J. García-Martínez ◽  
E. Jiménez-Martí ◽  
A. Mendes-Faia ◽  
...  
Keyword(s):  
Gene Expression ◽  
Saccharomyces Cerevisiae ◽  
Ribosomal Proteins ◽  
Ribosome Biogenesis ◽  
Alcoholic Fermentation ◽  
Expression Profiles ◽  
Nitrogen Concentration ◽  
Nitrogen Addition ◽  
Yeast Cells ◽  
Experimental Conditions

ABSTRACT Gene expression profiles of a wine strain of Saccharomyces cerevisiae PYCC4072 were monitored during alcoholic fermentations with three different nitrogen supplies: (i) control fermentation (with enough nitrogen to complete sugar fermentation), (ii) nitrogen-limiting fermentation, and (iii) the addition of nitrogen to the nitrogen-limiting fermentation (refed fermentation). Approximately 70% of the yeast transcriptome was altered in at least one of the fermentation stages studied, revealing the continuous adjustment of yeast cells to stressful conditions. Nitrogen concentration had a decisive effect on gene expression during fermentation. The largest changes in transcription profiles were observed when the early time points of the N-limiting and control fermentations were compared. Despite the high levels of glucose present in the media, the early responses of yeast cells to low nitrogen were characterized by the induction of genes involved in oxidative glucose metabolism, including a significant number of mitochondrial associated genes resembling the yeast cell response to glucose starvation. As the N-limiting fermentation progressed, a general downregulation of genes associated with catabolism was observed. Surprisingly, genes encoding ribosomal proteins and involved in ribosome biogenesis showed a slight increase during N starvation; besides, genes that comprise the RiBi regulon behaved distinctively under the different experimental conditions. Here, for the first time, the global response of nitrogen-depleted cells to nitrogen addition under enological conditions is described. An important gene expression reprogramming occurred after nitrogen addition; this reprogramming affected genes involved in glycolysis, thiamine metabolism, and energy pathways, which enabled the yeast strain to overcome the previous nitrogen starvation stress and restart alcoholic fermentation.

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