scholarly journals “Ouu-akaPL8”, new red rice line with hybrid weakness from the cultivar “JAMAICA”

2021 ◽  
Author(s):  
Hisatoshi Ohta ◽  
Narifumi Yokogami ◽  
Naoto Tsuda ◽  
Kentaro Fujimura ◽  
Akira Fukushima ◽  
...  
Keyword(s):  
Red Rice ◽  
Rice Line ◽  
Hybrid Weakness

scholarly journals AB0601 RAPID AND SUSTAINED EFFICACY OF AN INDUCTION TREATMENT WITH A TRIPLE THERAPY INCLUDING HIGH-DOSE INTRAVENOUS IMMUNOGLOBULINS, METHOTREXATE AND GLUCOCORTICOIDS IN ANTI-3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE MYOPATHY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1597.1-1597
Author(s):  
E. Treppo ◽  
M. Infantino ◽  
M. Benucci ◽  
V. Ravagnani ◽  
B. Palterer ◽  
...  
Keyword(s):  
Triple Therapy ◽  
Antibody Titer ◽  
Intravenous Immunoglobulins ◽  
High Dose ◽  
Sustained Remission ◽  
Red Rice ◽  
Gradual Improvement ◽  
High Doses ◽  
High Dose Ivig

Background:Anti-3-hydroxy-3-methylglutaryl-coenzime A reductase (HMGCR) myopathy is a new entity, which has been clearly associated to statin use, even if it can be diagnosed in patients without a history of exposure to statin or even in the childhood (1).Objectives:The aim of the study is to describe the efficacy of a triple therapy regimen consisting in high-doses of intravenous immunoglobulins (IVIG), methotrexate (MTX), and glucocorticoids (GC) in 16 patients with Anti-HMGCR myopathy enrolled in 6 specialized centres.Methods:A total of 16 patients with anti-HMGCR myopathy (7 females; 9 males) were collected. Mean (±standard deviation) age at the onset of disease was 72.4±10.3 years old. All patients were diagnosed having anti-HMGCR myopathy [anti-HMGCR antibodies were measured by chemiluminescence assay (BioFlash, Inova, CA)] (2). Median follow-up was 29.5 months (interquartile range: 15.75-60 months). Anti-HMGCR antibodies were available in the follow-up in 8/16 patients.Results:Thirteen out of 16 patients (81.3%) had been exposed to statin (1/13 to red rice), 3/16 (18.7%) were not exposed. As induction therapy, 11/16 patients have been treated with triple therapy (high-dose IVIG, MTX and GC), 2/16 with double therapy (high-dose IVIG and GC), 2/16 have been treated with GC alone, the patient exposed to red rice resolved only with red rice suspension. Clinical remission and normalization of CPK values within month +24 were obtained in all the patients. All the patients were in remission at the last follow-up. Gradual improvement started soon from the first month, and among the 13 patients treated with an aggressive immunosuppresssive therapy including IVIG (13/13), GC (13/13) and methotrexate (11/13), 9/13 normalized the CPK value within 6 months. Clinical and laboratory response was accompanied by significant decrease or normalization of the anti-HMGCR antibody titer. All the patients were either not taking GC (56.3%), or were taking low doses of GC (43.7%) at the last follow-up. Four patients had stopped GC within 6 months. No serious side effects were recorded. After persistent remission, a maintenance immunosuppressive therapy was then administered. Only 3 relapses in 3 different cases were recorded, all of them during drug-free remission in long-term follow-up. Reinduction was again effective in all.Conclusion:Anti-HMGCR myopathy is a rare and serious myopathy which usually affects older people during statin treatment. After statin suspension, a rapid and sustained remission can be achieved by induction with a triple aggressive therapy consisting in medium-to high doses of GC, high-dose IVIG, and MTX (3). GC should be tapered as soon as possible. Relapse appears infrequent during maintenance treatment. Monitoring anti-HMGCR antibody titer may be clinically relevant.References:[1]AL Mammen et al. N Engl J Med. 2016;374:664-9[2]Musset L et al. Autoimmun Rev. 2016;15:983-93.[3]Aggarwal A et al. Scand J Rheumatol. 2019; 1-7.Acknowledgments:We thank MD Francesca Grosso and MD Valentina Mecheri from the University of Florence, MD Angela Zuppa and MD Chiara De Michelis, from San Martino Hospital, Genova, for their valued collaboration in data collectionDisclosure of Interests:Elena Treppo: None declared, Maria Infantino: None declared, Maurizio Benucci: None declared, Viviana Ravagnani: None declared, Boaz Palterer: None declared, Marina Grandis: None declared, Martina Fabris: None declared, Paola Tomietto: None declared, Mariangela Manfredi: None declared, Arianna Sonaglia: None declared, Maria Grazia Giudizi: None declared, Francesca Ligobbi: None declared, Daniele Cammelli: None declared, Paola Parronchi: None declared, Salvatore De Vita Consultant of: Roche, GSK, Speakers bureau: Roche, GSK, Novartis, Luca Quartuccio Consultant of: Abbvie, Bristol, Speakers bureau: Abbvie, Pfizer

scholarly journals Performance of the agronomic traits of six advanced promising lines of red rice (oryza sativa l.) grown on the paddy field

2021 ◽  
Vol 681 (1) ◽  
pp. 012033
Author(s):  
G R Sadimantara ◽  
E Febrianti ◽  
LO Afa ◽  
S Leomo ◽  
Muhidin ◽  
...  
Keyword(s):  
Oryza Sativa ◽  
Paddy Field ◽  
Agronomic Traits ◽  
Oryza Sativa L ◽  
Red Rice

scholarly journals Beneficial Metabolic Effect of a Nutraceuticals Combination (Monacolin K, Yeasted Red Rice, Polyphenolic Extract of Annurca Apple and Berberine) on Acquired Hypercholesterolemia: A Prospective Analysis

Metabolites ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 223
Author(s):  
Roberta D’Assante ◽  
Mariarosaria De Luca ◽  
Sergio Ferraro ◽  
Andrea Ferraro ◽  
Antonio Ruvolo ◽  
...  
Keyword(s):  
Side Effects ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Public Health Problem ◽  
Metabolic Effect ◽  
Prospective Analysis ◽  
Flow Mediated Dilation ◽  
Red Rice ◽  
Cholesterol Reduction ◽  
Polyphenolic Extract

Hypercholesterolemia represents a serious public health problem as it significantly increases the risk of developing cardiovascular diseases. Its treatment with statin is limited by costs, side effects, and drugs interactions. Nutraceuticals appear to have an important metabolic effect on cholesterol reduction as well as on body weight and glycemia. The aim of this study was to evaluate the effect of a nutraceutical combination (Melasterol) in eighty-seven patients with acquired hypercholesterolemia. Clinically relevant parameters were collected at baseline and after three and six months of Melasterol treatment, one tablet per day. The primary endpoint was the change in cholesterol and triglyceride levels. Six months of treatment resulted in a 19.2% decrease in total cholesterol, accompanied by a 19.8% decrease in low-density lipoprotein (LDL) and a 23% reduction in triglycerides (p < 0.001) but not in high-density lipoprotein (HDL) levels (p > 0.05). These results were paralleled by a significative blood glucose (108.3 ± 21.3 vs. 98.4 ± 18.6 mg/dL p < 0.001) and body mass index (BMI) reduction (27.8 ± 4.4 vs. 27.0 ± 4.2 mg/dL, p < 0.001). A subgroup of 12 patients performed flow-mediated dilation, with values increasing by 1.8% (p < 0.05). No significant side effects were reported. Besides its cholesterol-lowering effect, Melasterol was associated with a significant improvement in other relevant metabolic parameters such as BMI and glycemia.

Red Rice (Oryza sativa) Control in Drill-Seeded Rice (O. sativa)

Weed Science ◽  
1985 ◽  
Vol 33 (5) ◽  
pp. 703-707 ◽  
Author(s):  
Amadou Diarra ◽  
Roy J. Smith ◽  
Ronald E. Talbert
Keyword(s):  
Oryza Sativa ◽  
Grain Yield ◽  
Field Experiments ◽  
Growing Season ◽  
Rice Cultivar ◽  
Rice Grain ◽  
Rice Seed ◽  
Red Rice ◽  
Culm Density ◽  
High Yields

Field experiments were conducted to investigate methods of controlling red rice (Oryza sativaL. ♯ ORYSA) in drill-seeded rice (O. sativa). Treatments included the rice cultivar ‘Mars', coated with calcium peroxide (CaO2) at 40% (w/w) and a crop protectant, R-33865 (O,O-diethyl-O-phenyl phosphorothioate) at 0.5 and 1% (v/w). Molinate (S-ethyl hexahydro-1H-azepine-1-carbothioate) at 6.7 kg ai/ha was applied preplant incorporated (ppi). The land was flooded (2.5 to 5 cm deep) after seeding with rice (100 kg/ha, 2.5 cm deep), and the water was maintained throughout the growing season. CaO2, with or without molinate, increased rice grain yield 50% and increased rice culm density fivefold above untreated rice. Molinate applied ppi controlled 96% of the red rice. Rice seed coated with only CaO2or with CaO2plus R-33865 at 0.5%, each combined with ppi molinate, produced 5690 and 6030 kg/ha of grain, respectively. These high yields were associated with red rice control by molinate and good stands of rice provided by O2supplied by CaO2. R-33865 applied to rice seed at 1% (v/w) injured rice by reducing rice culm densities 41%, compared with rice without protectant.

scholarly journals Innovative Fermented Beverages Made with Red Rice, Barley, and Buckwheat

Foods ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 613
Author(s):  
Federica Cardinali ◽  
Andrea Osimani ◽  
Vesna Milanović ◽  
Cristiana Garofalo ◽  
Lucia Aquilanti
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Nutritional Value ◽  
Ad Hoc ◽  
Consumer Demand ◽  
Red Rice ◽  
Healthy Foods ◽  
Biological Value ◽  
Fermented Beverages ◽  
Lifestyle Choices

The increase in food intolerances, allergies, and food-based lifestyle choices has dramatically increased the consumer demand for healthy foods characterized by pleasant sensory traits. In such a context, innovative cereal-based beverages are characterized by high nutritional value, pleasant palatability, and potential healthy properties. In the present study, a pool of 23 lactic acid bacteria strains was preliminary assayed as monocultures for the fermentation of three ad hoc formulated cereal- (red rice and barley) and pseudocereal (buckwheat) -based substrates. Eight strains with the best performance in terms of acidification rate were selected for the formulation of three multiple strain cultures to be further exploited for the manufacture of laboratory-scale prototypes of fermented beverages. The compositional and microbiological features of the three experimental beverages highlighted their high biological value for further exploitation.

scholarly journals IRGA 431 CL, new rice variety for red rice management in Southern Brazil

2018 ◽  
Vol 18 (4) ◽  
pp. 455-459
Author(s):  
Mara Cristina Barbosa Lopes ◽  
Sérgio Iraçu Gindri Lopes
Keyword(s):  
Rice Variety ◽  
Southern Brazil ◽  
Red Rice

Ankaflavin fromMonascus-Fermented Red Rice Exhibits Selective Cytotoxic Effect and Induces Cell Death on Hep G2 Cells

2005 ◽  
Vol 53 (6) ◽  
pp. 1949-1954 ◽  
Author(s):  
Nan-Wei Su ◽  
Yii-Lih Lin ◽  
Min-Hsiung Lee ◽  
Chen-Ying Ho
Keyword(s):  
Cell Death ◽  
Cytotoxic Effect ◽  
Red Rice ◽  
Hep G2 ◽  
Hep G2 Cells ◽  
G2 Cells
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