scholarly journals An Investigation of the Early Detection of Radiation Induced Apoptosis by 99mTc-Annexin V and 201Thallium-Chloride in a Lung Cancer Cell Line

2012 ◽  
Vol 53 (3) ◽  
pp. 361-367 ◽  
Author(s):  
Mahbub e KHODA ◽  
Keita UTSUNOMIYA ◽  
Sangkil HA-KAWA ◽  
Shohei KANNO ◽  
Yumiko KONO ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Early Detection ◽  
Cell Line ◽  
Cancer Cell Line ◽  
Annexin V ◽  
Lung Cancer Cell Line ◽  
Lung Cancer Cell ◽  
Thallium Chloride ◽  
Radiation Induced ◽  
Induced Apoptosis

Cytotoxic effect induced apoptosis in lung cancer cell line on Ageratina adenophora leaf extract

2019 ◽  
Vol 22 ◽  
pp. 101381
Author(s):  
Suganya Mani ◽  
Karthik Natesan ◽  
Kavitha Shivaji ◽  
Mythili Gnanamangai Balasubramanian ◽  
Ponmurugan Ponnusamy
Keyword(s):  
Lung Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Cytotoxic Effect ◽  
Leaf Extract ◽  
Cancer Cell Line ◽  
Lung Cancer Cell Line ◽  
Lung Cancer Cell ◽  
Ageratina Adenophora ◽  
Induced Apoptosis

Demonstration of radiation-induced bystander effect in a human lung cancer cell line

2010 ◽  
Vol 7 (4) ◽  
pp. 298
Author(s):  
Mohammad T. Bahreyni Toossi ◽  
Shokoohozaman Soleymanifard ◽  
Mahmoud Mahmoudi ◽  
Ameneh Sazgarnia
Keyword(s):  
Lung Cancer ◽  
Cell Line ◽  
Bystander Effect ◽  
Human Lung ◽  
Cancer Cell Line ◽  
Lung Cancer Cell Line ◽  
Human Lung Cancer ◽  
Lung Cancer Cell ◽  
Radiation Induced ◽  
Radiation Induced Bystander Effect

The Role of NF-kappaB in the TNF-alpha-induced Apoptosis of Lung Cancer Cell Line

2000 ◽  
Vol 48 (2) ◽  
pp. 166
Author(s):  
J Y Kim ◽  
S H Lee ◽  
B Hwangbo ◽  
C T Lee ◽  
O H Kim ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Lung Cancer Cell Line ◽  
Tnf Alpha ◽  
Lung Cancer Cell ◽  
Nf Kappab ◽  
Induced Apoptosis

scholarly journals Sepia Ink Oligopeptide Induces Apoptosis of Lung Cancer Cells via Mitochondrial Pathway

2018 ◽  
Vol 45 (5) ◽  
pp. 2095-2106 ◽  
Author(s):  
Xiaohua Wang ◽  
Cheng Chen ◽  
Guoren Zhou ◽  
Jinjun Ye ◽  
Rong Yin ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Proliferation ◽  
Cell Line ◽  
Cancer Cell ◽  
Death Receptor ◽  
Cancer Cell Line ◽  
Mitochondrial Pathway ◽  
Lung Cancer Cell Line ◽  
Lung Cancer Cell ◽  
Induced Apoptosis

Background/Aims: Our previous study suggested the anti-tumor activity of sepia ink oligopeptide (SIO). Here we sought to investigate the underlying molecular mechanism. Methods: Cell proliferation was evaluated by cell counting kit-8 (CCK-8) assay. Cell apoptosis was determined by Annexin V/Propidium Iodide (PI) staining. The mitochondria pathway was characterized by quantification of Bcl-2, Bax, Caspase-9 and Cyto-C. The death receptor pathway was analyzed by determinement of Fas, Caspase-8 and NIK. The endoplasmic reticulum (ER)-dependent pathway was determined by measurement the expression of CHOP, Caspase-12, GRP78 and Calpain. The associated gene expression was quantified by RT-PCR and protein level was determined by immunoblotting. Results: We demonstrated treatment with structurally modified SIO (CSIO, 5 µM) significantly inhibited cell proliferation and induced apoptosis in lung cancer cell line A549. The mitochondrial pathway, death receptor pathway and ER stress induced apoptosis were stimulated upon CSIO treatment. The administration with respective inhibitors including midiv-1 (50 µM for 2 h), PDTC (20 µM PDTC for 30 min) and ALLN (20 mM ALLN for 5 h) readily reversed the apoptosis inducing effect of CSIO. Conclusion: Our data demonstrates that CSIO is capable of induction apoptosis in lung cancer cell line, which is mediated by all three classical apoptotic pathways. Our results warrant further in vivo investigations of the anti-tumor potential of CSIO.

Toxic effect of TiO2 nanoparticles against human lung cancer cell line A549

2011 ◽  
Vol 31 (10) ◽  
pp. 1091-1095
Author(s):  
Xiao-lin LI ◽  
Yan-fang ZHANG ◽  
Kai TANG ◽  
Ying TANG ◽  
Ruo-bing JIN ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Toxic Effect ◽  
Cell Line ◽  
Cancer Cell ◽  
Human Lung ◽  
Cancer Cell Line ◽  
Lung Cancer Cell Line ◽  
Human Lung Cancer ◽  
Lung Cancer Cell ◽  
Human Lung Cancer Cell
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