scholarly journals Talent as an unintentional agent

Bioethica ◽  
2015 ◽  
Vol 1 (2) ◽  
pp. 38
Author(s):  
Konstantinos Papageorgiou (Κωνσταντίνος Παπαγεωργίου)
Keyword(s):  
Functional Food ◽  
High Performance ◽  
Applied Ethics ◽  
Drug Side Effects ◽  
Exposure Limits ◽  
First Case ◽  
Single Person ◽  
Scope Of Application ◽  
Permissible Exposure Limits ◽  
Novel Concept

Unintentional exposure is a novel concept. No single person has coined the term. It mainly refers to substances and activities affecting individuals without their consent – be it informed or not. In the broader field of applied ethics in general, and of bioethics in particular, the scope of application extends from nutrition (GM, functional food), to pollution (chemical-, air-, light-, noise-, radioactive contamination etc.), climate change, embryo rights, drug side-effects (especially in regard to chemotherapy), radiation (e.g. food), Permissible Exposure Limits, education and (bio-)terrorism. In the discussion about talent and giftedness1 there are two main approaches or schools of thought. On one hand, talent is conceived as an exclusive agent, in that some individuals are born more capable than others. On the other hand, a different school of thought advocates the modification of body and mind of all individuals in order for them to achieve similar levels of high performance. In the first case, individuals are bound to their nature, while in the latter instance they are prisoners of their environment –two equivalent positions in terms of autonomy and freedom. The latter will be argued to be the case; as a result, a connection with unintentional exposure will be established.

Study of Transcrystallization in Polymer Composites

1989 ◽  
Vol 170 ◽  
Author(s):  
Benjamin S. Hsiao ◽  
J. H. Eric
Keyword(s):  
Thermal Conductivity ◽  
Free Energy ◽  
Carbon Fiber ◽  
Plasma Treatment ◽  
Polymer Composites ◽  
High Performance ◽  
Interfacial Strength ◽  
Fiber Surface ◽  
Semicrystalline Polymers ◽  
First Case

AbstractTranscrystallization of semicrystalline polymers, such as PEEK, PEKK and PPS, in high performance composites has been investigated. It is found that PPDT aramid fiber and pitch-based carbon fiber induce a transcrystalline interphase in all three polymers, whereas in PAN-based carbon fiber and glass fiber systems, transcrystallization occurs only under specific circumstances. Epitaxy is used to explain the surface-induced transcrystalline interphase in the first case. In the latter case, transcrystallization is probably not due to epitaxy, but may be attributed to the thermal conductivity mismatch. Plasma treatment on the fiber surface showed a negligible effect on inducing transcrystallization, implying that surface-free energy was not important. A microdebonding test was adopted to evaluate the interfacial strength between the fiber and matrix. Our preliminary results did not reveal any effect on the fiber/matrix interfacial strength of transcrystallinity.

Ototoxicity of trichloroethylene in concentrations relevant for the working environment

2008 ◽  
Vol 27 (3) ◽  
pp. 195-200 ◽  
Author(s):  
A Vyskocil ◽  
T Leroux ◽  
G Truchon ◽  
F Lemay ◽  
F Gagnon ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Convincing Evidence ◽  
Working Environment ◽  
Exposure Limits ◽  
Additive Interaction ◽  
Animal Data ◽  
Short Term Exposure ◽  
Adverse Effect Level ◽  
Effect Level ◽  
Permissible Exposure Limits

Organic solvents can cause hearing loss themselves or promote noise-induced hearing loss. The objective of this study was to review the literature on the effects of low-level exposure to trichloroethylene on the auditory system and consider its relevance for the occupational settings. Both human and animal investigations were evaluated only for realistic exposure concentrations based on the Quebec permissible exposure limits: 50 ppm 8-h time-weighed average exposure value (TWAEV) and 200 ppm short-term exposure value (STEV). In humans, the upper limit for considering ototoxicity data relevant to the occupational exposure situation was set at the STEV. Animal data were evaluated only for exposure concentrations up to 100 times the TWAEV. There is no convincing evidence of trichloroethylene-induced hearing losses in workers. In rats, trichloroethylene affects the auditory function mainly in the cochlear mid- to high-frequency range with a lowest observed adverse effect level (LOAEL) of 2000 ppm. No studies on ototoxic interaction after combined exposure to noise and trichloroethylene were identified in humans. In rats, supra-additive interaction was reported. Further studies with sufficient data on the trichloroethylene exposure of workers are necessary to make a definitive conclusion. In the interim, we recommend considering trichloroethylene as an ototoxic agent.

Pulsed TIG Welding of Aluminum

2019 ◽  
Author(s):  
S. Katoh
Keyword(s):  
Arc Welding ◽  
High Performance ◽  
Control Function ◽  
Tig Welding ◽  
Inert Gas ◽  
Pulsed Arc Welding ◽  
Scope Of Application ◽  
Practical Performance ◽  
Pulsed Tig Welding ◽  
Pulsed Arc

As a consequence of developments in the electronic control of welding power sources, there has been a trend for even inexpensive and widely used metal inert gas (MIG) and tungsten inert gas (TIG) welding machines to be equipped, as standard, with a high performance pulsed current waveform control function. Meanwhile advances in understanding of pulsed arc welding phenomena and the clarification of the associated functional effects have resulted in a gradual expansion of its scope of application and of improvements in practical performance. Thus inert gas shielded arc welding is entering an epoch when full scale pulsed arc welding will become standard. In this article, the progress of the development of pulsed TIG welding of aluminium is introduced, followed by a description of the main characteristics and finally examples of recent research concerning the improvement of weld quality are introduced.

scholarly journals Haemoglobin Olympia {β Codon 20 (B2) G→A, Val→Met}: A Silent Haemoglobin Variant

2021 ◽  
Author(s):  
Abhay A Bhave ◽  
Lakshmi Iyer ◽  
Nawal Kazi ◽  
Manju Gorivale ◽  
Anita Nadkarni
Keyword(s):  
High Performance ◽  
Extended Family ◽  
Globin Gene ◽  
Oxygen Affinity ◽  
High Oxygen ◽  
Cerebral Vessel ◽  
Haemoglobin Variant ◽  
First Case ◽  
History Of ◽  
High Oxygen Affinity

High oxygen affinity haemoglobin variants are rare and often underdiagnosed in persistent erythrocytosis with no apparent aetiology. Here the author present a 29-year-old Indian male patient with a long-standing history of erythrocytosis which was incidentally detected. The proband had a prothrombotic family history of cerebral vessel stroke in his paternal grandfather at a young age and unexplained erythrocytosis in his father and brother. A review of his haemograms showed persistent high haemoglobin values. Routine tests did not reveal any specific aetiology and haemoglobin electrophoresis by High-Performance Liquid Chromatography (HPLC) showed absence of any abnormal peak or unstable haemoglobin. DNA sequencing of the β globin gene revealed heterozygosity for codon 20 {GTG→ATG, Valine (Val)→ Methionine (Met)} mutation confirming the presence of an electrophoretically silent Hb variant - Haemoglobin Olympia in him and his extended family members. This case study emphasises importance of this rare entity of high oxygen affinity haemoglobin variant as a differential diagnosis while screening for erythrocytosis. This is the first case report of Haemoglobin Olympia from India reported in the literature.

scholarly journals Sailors and the Risk of Asbestos-Related Cancer

2021 ◽  
Vol 18 (16) ◽  
pp. 8417
Author(s):  
Richard Lemen ◽  
Philip Landrigan
Keyword(s):  
Premature Death ◽  
Epidemiologic Studies ◽  
Exposure Limits ◽  
Related Disease ◽  
Occupationally Exposed ◽  
Amphibole Asbestos ◽  
Permissible Exposure Limits ◽  
Asbestos Related Disease ◽  
Risk Of Exposure ◽  
Shipyard Workers

Sailors have long been known to experience high rates of injury, disease, and premature death. Many studies have shown asbestos-related diseases among shipyard workers, but few have examined the epidemiology of asbestos-related disease and death among asbestos-exposed sailors serving on ships at sea. Chrysotile and amphibole asbestos were used extensively in ship construction for insulation, joiner bulkhead systems, pipe coverings, boilers, machinery parts, bulkhead panels, and many other uses, and asbestos-containing ships are still in service. Sailors are at high risk of exposure to shipboard asbestos, because unlike shipyard workers and other occupationally exposed groups, sailors both work and live at their worksite, making asbestos standards and permissible exposure limits (PELs). based on an 8-hour workday inadequate to protect their health elevated risks of mesothelioma and other asbestos-related cancers have been observed among sailors through epidemiologic studies. We review these studies here.

scholarly journals Two familial cases of Hb Tyne confirm instability as cause of low expression

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Beverley M. Pullon ◽  
Stephen O. Brennan
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Cation Exchange ◽  
High Performance ◽  
Blood Count ◽  
Full Blood Count ◽  
Familial Cases ◽  
First Case ◽  
Β Chain ◽  
Low Expression

We report a second occurrence of hemoglobin (Hb) Tyne, [β5 (A2) Pro>Ser] HBB:c.16C>T(p.Pro6Ser), which like the first case was associated with normal hematology. We verified the variant was mildly unstable by showing it was greatly enriched in isopropanol precipitates. This minor instability accounts for the slightly decreased expression of the new β chain. The variant was picked up as an interfering component on HbA1c testing using cation exchange high performance liquid chromatography (HPLC). However, this may be an advantage in detecting electrophoretically silent variants. Furthermore, this report also highlights the importance of uneven or sloping baselines on HPLC, which could reflect the presence of a variant hemoglobin even in the presence of normal electrophoresis and full blood count. 我们报告了第二例血红蛋白(Hb) Tyne [β5 (A2) Pro>Ser] HBB:c.16C>T(p.Pro6Ser)的出现，其与第一例一样伴随血象正常。我们通过将该变体在异丙醇沉淀物中的显著富集证实了其有轻度不稳定性。这种微小的不稳定性可用来说明新β链表达的轻微下降。该变体在使用阳离子交换高效液相色谱（HPLC）的HbA1c检测中作为干扰成分检出。然而，在检测电泳沉默变体方面这可能使一个优势。此外，本报告还强调了不平或倾斜的基线对HPLC的重要性，这会反映出血红蛋白变异体的存在，即使电泳和全血计数正常。

KEEPING THE OSHA PERMISSIBLE EXPOSURE LIMITS CURRENT

AIHAJ ◽  
1990 ◽  
Vol 51 (10) ◽  
pp. A-679-A-686
Author(s):  
Harry J. Ettinger
Keyword(s):  
Exposure Limits ◽  
Permissible Exposure Limits

scholarly journals Optical Harmonic Vernier Effect: A New Tool for High Performance Interferometric Fiber Sensors

Sensors ◽  
2019 ◽  
Vol 19 (24) ◽  
pp. 5431 ◽  
Author(s):  
André D. Gomes ◽  
Marta S. Ferreira ◽  
Jörg Bierlich ◽  
Jens Kobelke ◽  
Manfred Rothhardt ◽  
...  
Keyword(s):  
High Performance ◽  
Magnification Factor ◽  
Fiber Sensors ◽  
Novel Approach ◽  
Fabry Perot ◽  
Interference Signals ◽  
Fabrication Tolerances ◽  
Vernier Effect ◽  
Novel Concept ◽  
Optical Harmonic

The optical Vernier effect magnifies the sensing capabilities of an interferometer, allowing for unprecedented sensitivities and resolutions to be achieved. Just like a caliper uses two different scales to achieve higher resolution measurements, the optical Vernier effect is based on the overlap in the responses of two interferometers with slightly detuned interference signals. Here, we present a novel approach in detail, which introduces optical harmonics to the Vernier effect through Fabry–Perot interferometers, where the two interferometers can have very different frequencies in the interferometric pattern. We demonstrate not only a considerable enhancement compared to current methods, but also better control of the sensitivity magnification factor, which scales up with the order of the harmonics, allowing us to surpass the limits of the conventional Vernier effect as used today. In addition, this novel concept opens also new ways of dimensioning the sensing structures, together with improved fabrication tolerances.

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