scholarly journals Research Progress on Chemical Constituents of Acorus tatarinowii schott and Their Pharmacological Activities on Central Nervous System

2017 ◽  
Vol 06 (05) ◽  
pp. 133-141
Author(s):  
洁 杨
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Chemical Constituents ◽  
Research Progress ◽  
Pharmacological Activities ◽  
Acorus Tatarinowii

scholarly journals Lavandulae aetheroleum Oil: A Review on Phytochemical Screening, Medicinal Applications, and Pharmacological Effects

2020 ◽  
Vol 11 (3) ◽  
pp. 9836-9847
Keyword(s):  
Central Nervous System ◽  
Clinical Pharmacology ◽  
Nervous System ◽  
Chemical Constituents ◽  
Cardiovascular Effects ◽  
Pharmacological Effects ◽  
Lavandula Angustifolia ◽  
Experimental Pharmacology ◽  
Central Nervous System Depressant ◽  
Anti Inflammatory

Lavandulae aetheroleum, the oil, was obtained by vapor condensation from the flower of Lavandula angustifolia Mill. or Lavandula intermedia Loisel (Lamiaceae) plant. Other names of Lavandulae aetheroleum oil are Al birri, common or English lavender. The Lavandula angustifolia Mill. or Lavandula intermedia Loisel plant is spreading in the Mediterranean, southern Europe, Bulgaria, Russia, and USA. The Lavandula angustifolia Mill. or Lavandula intermedia Loisel plant, is an odor shrub with 1-2 m in height. The oil is a clear, colorless, or pale yellow. The gas chromatography studies reported the following percentage of the major chemical constituents in the oil: linalyl acetate (25-46%), linalool (20-45%), terpinen-4-ol (1.2-6.0%), lavendulyl acetate (> 1.0%), 1,8-cineole (1,8-cineol, cineol, cineole, eucalyptol) (< 2.5%), 3-octanone (< 2.5%), camphor (< 1.2%), limonene (< 1.0%), and α-terpineol (< 2.0%). Medicinal applications of the oil include the treatment of restlessness, anxiety, cardiovascular disorders, insomnia, and gastrointestinal disorders, burns, diarrhea, headache, sore throats, and wounds. Pharmacological effects include experimental and clinical pharmacology. Experimental pharmacology includes anesthetic, anticonvulsant, sedative, anti-inflammatory, antimicrobial, antispasmodic, antispasmodic, central nervous system depressant effects. Clinical pharmacology includes anxiolytic, analgesic, and cardiovascular effects. The oil dose by inhalation = 0.06-0.2 ml/ 3 times/day while oil dose internally = 1-4 drops approximately 20-80 mg on a sugar cube per day. In conclusion, Lavandulae aetheroleum oil had an anesthetic, anticonvulsant, sedative, anti-inflammatory, antimicrobial, antispasmodic, antispasmodic, central nervous system depressant, anxiolytic, analgesic, and cardiovascular effects.

scholarly journals Research progress on adenosine in central nervous system diseases

2019 ◽  
Vol 25 (9) ◽  
pp. 899-910 ◽  
Author(s):  
Ying‐Jiao Liu ◽  
Jiao Chen ◽  
Xun Li ◽  
Xin Zhou ◽  
Yao‐Mei Hu ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Research Progress ◽  
Nervous System Diseases ◽  
Central Nervous System Diseases

scholarly journals Research Progress on the Effect of Sphingosine Kinase 2 on Glioma

2021 ◽  
Vol 5 (6) ◽  
pp. 16-19
Author(s):  
Chunpeng Wang ◽  
Xiaohui Liu ◽  
Shiwen Guo
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Sphingosine Kinase ◽  
Immunohistochemical Method ◽  
Research Progress ◽  
Control Group ◽  
Sphingosine Kinase 2 ◽  
Two Factors ◽  
The Central Nervous System

Objective: The purpose of this study is to explore the role of sphingosine kinase 2 (SphK2) in the treatment of glioma, which is the most common primary tumor in the central nervous system. Methods: A total of 82 patients were included in this study, with 27 cases in the control group and 55 cases in the glioma group; the expressions of SphK2 and gp130 in the two groups were compared by immunohistochemical method, and the correlation between the two factors was analyzed. Results: Both SphK2 and gp130 were upregulated in the glioma group, and the two factors were significantly correlated. Conclusion: The high expression of SphK2 may play an important role in the occurrence, development, and diagnosis of glioma.

scholarly journals Research Progress and Challenges in the Treatment of Central Nervous System Metastasis of Non-Small Cell Lung Cancer

Cells ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2620
Author(s):  
Bin Wang ◽  
Hanfei Guo ◽  
Haiyang Xu ◽  
Hongquan Yu ◽  
Yong Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Research Progress ◽  
High Morbidity ◽  
Small Cell Lung ◽  
Cns Metastasis

Non-small cell lung cancer (NSCLC) is one of the most common malignant tumors and has high morbidity and mortality rates. Central nervous system (CNS) metastasis is one of the most frequent complications in patients with NSCLC and seriously affects the quality of life (QOL) and overall survival (OS) of patients, with a median OS of untreated patients of only 1–3 months. There are various treatment methods for NSCLC CNS metastasis, including surgery, chemotherapy, radiotherapy, targeted therapy, and immunotherapy, which do not meet the requirements of patients in terms of improving OS and QOL. There are still many problems in the treatment of NSCLC CNS metastasis that need to be solved urgently. This review summarizes the research progress in the treatment of NSCLC CNS metastasis to provide a reference for clinical practice.

scholarly journals NLRC5: A Potential Target for Central Nervous System Disorders

2021 ◽  
Vol 12 ◽  
Author(s):  
Lu Zhang ◽  
Cui Jiao ◽  
Lingjuan Liu ◽  
Aiping Wang ◽  
Li Tang ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neuronal Development ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Nuclear Factor Κb ◽  
Research Progress ◽  
Cns Infection ◽  
Type I ◽  
Nucleotide Oligomerization

Nucleotide oligomerization domain-like receptors (NLRs), a class of pattern recognition receptors, participate in the host’s first line of defense against invading pathogenic microorganisms. NLR family caspase recruitment domain containing 5 (NLRC5) is the largest member of the NLR family and has been shown to play an important role in inflammatory processes, angiogenesis, immunity, and apoptosis by regulating the nuclear factor-κB, type I interferon, and inflammasome signaling pathways, as well as the expression of major histocompatibility complex I genes. Recent studies have found that NLRC5 is also associated with neuronal development and central nervous system (CNS) diseases, such as CNS infection, cerebral ischemia/reperfusion injury, glioma, multiple sclerosis, and epilepsy. This review summarizes the research progress in the structure, expression, and biological characteristics of NLRC5 and its relationship with the CNS.

scholarly journals PHYTOCHEMISTRY AND PHARMACOLOGICAL PROFILE OF TRADITIONALLY USED MEDICINAL PLANT ARGYREIA SPECIOSA (LINN. F.)

2018 ◽  
Vol 8 (5-s) ◽  
pp. 41-46
Author(s):  
Bhagat Singh Jaiswal ◽  
Mukul Tailang
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Medicinal Plant ◽  
Pharmacological Activity ◽  
Local Health ◽  
Pharmacological Profile ◽  
Pharmacological Activities ◽  
Central Nervous System Depressant ◽  
Argyreia Nervosa ◽  
Anti Inflammatory

Argyreia speciosa (Linn.f.) (Family: Convolvulaceae, Synonyms: Argyreia nervosa) is used in the traditional Ayurvedic systems of medicine as well as in local health folklore. It is commonly known as Vidhaara in Hindi and Hawaiian Baby Woodrose and Elephant creeper in English. It is the large climber and seen throughout India up to an altitude of 500 m. A. speciosa possess various pharmacological activity such as anti-aging, gastroprotective, analgesic & anti-inflammatory, aphrodisiac, antiviral, antidiabetic,  anticonvulsion, antioxidant, antidiarrheal, antiulcer, central nervous system depressant, nematocides, nootropic, anticancer and many more. Apart from this numerous phytoconstituents have been isolated from A. speciosa. Its seeds principally contain lysergamides, eragine and isoeragine which responsible for its hallucinogenic properties. The present paper efforts bring to light the available literature on A. speciosa with respect to traditional, ethnobotanical, phytoconstituents and review of different pharmacological activities. Keywords: Argyreia speciosa, Vidhaara, Anti-aging, Hallucinogen, Ethnobotanical

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