scholarly journals Expression and Localization of TRK-Fused Gene Products in the Rat Brain and Retina

2012 ◽  
Vol 45 (4) ◽  
pp. 239 ◽  
Author(s):  
Hisae Maebayashi ◽  
Shigako Takeuchi ◽  
Chiaki Masuda ◽  
Satoshi Makino ◽  
Kenji Fukui ◽  
...  
Keyword(s):  
Rat Brain ◽  
Gene Products ◽  
Fused Gene

scholarly journals Expression and Localization of TRK-Fused Gene Products in the Rat Brain and Retina

2012 ◽  
Vol 45 (1) ◽  
pp. 15-23 ◽  
Author(s):  
Hisae Maebayashi ◽  
Shigako Takeuchi ◽  
Chiaki Masuda ◽  
Satoshi Makino ◽  
Kenji Fukui ◽  
...  
Keyword(s):  
Rat Brain ◽  
Gene Products ◽  
Fused Gene

scholarly journals A monoclonal antibody distinguishes two types of phosphatidylinositol 4-kinase

1991 ◽  
Vol 273 (1) ◽  
pp. 63-66 ◽  
Author(s):  
G C Endemann ◽  
A Graziani ◽  
L C Cantley
Keyword(s):  
Monoclonal Antibody ◽  
Rat Brain ◽  
Rat Liver ◽  
Bovine Brain ◽  
Human Erythrocytes ◽  
Gene Products ◽  
Type Ii ◽  
Type Iii ◽  
Distinct Gene ◽  
Phosphatidylinositol 4

A monoclonal antibody has been developed against the type II PtdIns 4-kinase from bovine brain. This antibody, 4C5G, causes greater than 90% inhibition of the type II PtdIns 4-kinase from bovine brain, rat brain and human erythrocytes. However, it fails to inhibit type III PtdIns 4-kinase from bovine brain or PtdIns 3-kinase from rat liver. These results suggest that type II and type III PtdIns 4-kinases are distinct gene products, and that 4C5G will be useful in studying the function of the type II PtdIns 4-kinase.

scholarly journals Differentiation and Death of Premyelinating Oligodendrocytes in Developing Rodent Brain

1997 ◽  
Vol 137 (2) ◽  
pp. 459-468 ◽  
Author(s):  
Bruce D. Trapp ◽  
Akiko Nishiyama ◽  
David Cheng ◽  
Wendy Macklin
Keyword(s):  
Cerebral Cortex ◽  
Corpus Callosum ◽  
Rat Brain ◽  
Protein Gene ◽  
Proteolipid Protein ◽  
Gene Products ◽  
Rodent Brain ◽  
Developing Rat

Previous studies have indicated that newly formed oligodendrocytes are dynamic cells whose production, survival, and differentiation depend upon axonal influences. This study has characterized the appearance and fate of newly formed oligodendrocytes in developing rat brain. Oligodendrocytes appear in predictable locations and radially extend DM-20–positive processes that cover 80-μm domains in the cortex and 40-μm domains in the corpus callosum. These premyelinating oligodendrocytes have one of two fates: they myelinate axons or degenerate. Between 7 and 21 d after birth, ∼20% of premyelinating oligodendrocytes identified in the cerebral cortex were degenerating. Oligodendrocytes that ensheathed axons expressed and selectively targeted proteolipid protein to compact myelin and did not degenerate. These observations support the hypothesis that axonal influences affect oligodendrocyte survival, differentiation, and expression of proteolipid protein gene products.

scholarly journals Immunohistochemical Mapping of TRK-Fused Gene Products in the Rat Brainstem

2012 ◽  
Vol 45 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Shigeko Takeuchi ◽  
Chiaki Masuda ◽  
Hisae Maebayashi ◽  
Ikuo Tooyama
Keyword(s):  
Gene Products ◽  
Rat Brainstem ◽  
Fused Gene

Mechanisms of Acute Uremic Encephalopathy: Early Activation of Fos and Fra-2 Gene Products in Different Nuclei/Areas of the Rat Brain

2010 ◽  
Vol 20 (5) ◽  
pp. S44-S50 ◽  
Author(s):  
August Heidland ◽  
Katarina Sebekova ◽  
André Klassen ◽  
Miklós Palkovits
Keyword(s):  
Rat Brain ◽  
Gene Products ◽  
Uremic Encephalopathy ◽  
Early Activation

Localization and subcellular distribution of cellular ras gene products in rat brain

1989 ◽  
Vol 5 (1) ◽  
pp. 31-44 ◽  
Author(s):  
Akira Mizoguchi ◽  
Takashi Ueda ◽  
Kazuto Ikeda ◽  
Hiroshi Shiku ◽  
Humio Mizoguti ◽  
...  
Keyword(s):  
Rat Brain ◽  
Subcellular Distribution ◽  
Gene Products ◽  
Ras Gene

scholarly journals Immunohistochemical Mapping of TRK-Fused Gene Products in the Rat Brainstem

2012 ◽  
Vol 45 (4) ◽  
pp. 240
Author(s):  
Shigeko Takeuchi ◽  
Chiaki Masuda ◽  
Hisae Maebayashi ◽  
Ikuo Tooyama
Keyword(s):  
Gene Products ◽  
Rat Brainstem ◽  
Fused Gene

Identification of a baculovirus polyhedron formation mutant with a novel phenotype

1996 ◽  
Vol 54 ◽  
pp. 796-797
Author(s):  
James M. Slavicek ◽  
Melissa J. Mercer ◽  
Mary Ellen Kelly
Keyword(s):  
Viral Gene ◽  
Gene Products ◽  
Type Number ◽  
Infection Cycle ◽  
Wild Type ◽  
Protein Matrix ◽  
Insect Midgut ◽  
Viral Particles ◽  
Budded Virus ◽  
Viral Form

Nucleopolyhedroviruses (NPV, family Baculoviridae) produce two morphological forms, a budded virus form and a viral form that is occluded into a paracrystalline protein matrix. This structure is termed a polyhedron and is composed primarily of the protein polyhedrin. Insects are infected by NPVs after ingestion of the polyhedron and release of the occluded virions through dissolution of the polyhedron in the alkaline environment of the insect midgut. Early after infection the budded virus form is produced. It buds through the plasma membrane and then infects other cells. Later in the infection cycle the occluded form of the virus is generated (reviewed by Blissard and Rohrmann, 1990).The processes of polyhedron formation and virion occlusion are likely to involve a number of viral gene products. However, only two genes, the polyhedrin gene and 25K FP gene, have been identified to date that are necessary for the wild type number of polyhedra to be formed and viral particles occluded.

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