scholarly journals Immunohistochemical characterization of vascular endothelial cells in cutaneous T-cell malignancies with special references to heterogenous expression of surface antigens associated with monocytes and macrophages.

1991 ◽  
Vol 24 (4) ◽  
pp. 377-387
Author(s):  
SHIGEAKI MORI ◽  
HATSUMI FUJII ◽  
TAKASHI YASUE ◽  
MASARU OHASHI ◽  
HARUO OHTANI ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
T Cell ◽  
Vascular Endothelial Cells ◽  
Surface Antigens ◽  
Vascular Endothelial ◽  
Monocytes And Macrophages ◽  
T Cell Malignancies

372: IL-10 inhibits endothelium-dependent T-cell costimulation by upregulation of ILT3/4 in human vascular endothelial cells

2007 ◽  
Vol 26 (2) ◽  
pp. S193
Author(s):  
C.A. Gleissner ◽  
M.H. Konstandin ◽  
S. Celik ◽  
R. Klingenberg ◽  
T. Giese ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
T Cell ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial

Molecular cloning and characterization of antigens expressed on rat tumor vascular endothelial cells

2000 ◽  
Vol 86 (6) ◽  
pp. 799-805 ◽  
Author(s):  
Kenji Taniguchi ◽  
Naoki Harada ◽  
Iwao Ohizumi ◽  
Michiko Kinoshita ◽  
Yasuo Tsutsumi ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Molecular Cloning ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Rat Tumor

scholarly journals The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells.

1996 ◽  
Vol 183 (5) ◽  
pp. 2185-2195 ◽  
Author(s):  
A Imura ◽  
T Hori ◽  
K Imada ◽  
T Ishikawa ◽  
Y Tanaka ◽  
...  
Keyword(s):  
T Cells ◽  
Endothelial Cells ◽  
T Cell ◽  
Cell Line ◽  
Cell Lines ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Cell Leukemia ◽  
Activated T Cells ◽  
T Cell Lines

Fresh leukemic cells from patients with adult T cell leukemia (ATL) and some ATL-derived T cell lines show adhesion to human umbilical vein endothelial cells (HUVECs) mainly through E-selectin, but a proportion of this binding remains unaffected by the addition of combinations of antibodies against known adhesion molecules. By immunizing mice with one of such cell lines, we established monoclonal antibodies (mAbs), termed 131 and 315, that recognize a single cell surface antigen (Ag) and inhibit the remaining pathway of the adhesion. These mAbs did not react with normal resting peripheral blood mononuclear cells (PBMC) or most of the cell lines tested except for two other human T cell leukemia virus type I (HTLV-I)-infected T cell lines. After stimulation with phytohemagglutinin (PHA), PBMC expressed Ag 131/315 transiently, indicating that these mAbs define a T cell activation Ag. Western blotting and immunoprecipitation revealed that Ag 131/315 has an apparent molecular mass of 50 kD. Expression cloning was done by transient expression in COS-7 cells and immunological selection to isolate a cDNA clone encoding Ag 131/315. Sequence analysis of the cDNA indicated that it is identical to human OX40, a member of the tumor necrosis factor/nerve growth factor receptor family. We then found that gp34, the ligand of OX40, was expressed on HUVECs and other types of vascular endothelial cells. Furthermore, it was shown that the adhesion of CD4+ cells of PHA-stimulated PBMC to unstimulated HUVECs was considerably inhibited by either 131 or 315. Finally, OX40 transfectants of Kit 225, a human interleukin 2-dependent T cell line, were bound specifically to gp34 transfectants of MMCE, a mouse epithelial cell line, and this binding was blocked by either 315 or 5A8, an anti-gp34 mAb. These results indicate that the OX40/gp34 system directly mediates adhesion of activated T cells or OX40+-transformed T cells to vascular endothelial cells.

Vascular endothelial cells enhance T cell responses by markedly augmenting IL-2 concentrations

1989 ◽  
Vol 118 (1) ◽  
pp. 166-177 ◽  
Author(s):  
Eva C. Guinan ◽  
Brian R. Smith ◽  
John T. Doukas ◽  
Richard A. Miller ◽  
Jordan S. Pober
Keyword(s):  
Endothelial Cells ◽  
T Cell ◽  
Vascular Endothelial Cells ◽  
T Cell Responses ◽  
Vascular Endothelial ◽  
Cell Responses

Isolation and characterization of vascular endothelial cells derived from fetal tooth buds of miniature swine

2013 ◽  
Vol 49 (3) ◽  
pp. 189-195 ◽  
Author(s):  
Masanori Nasu ◽  
Taka Nakahara ◽  
Noriko Tominaga ◽  
Yuichi Tamaki ◽  
Yoshiaki Ide ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Miniature Swine ◽  
Isolation And Characterization ◽  
Tooth Buds
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