scholarly journals Cytochemical localization of alkaline phosphatase in the spinal cord ependyma of newborn and adult rats.

1983 ◽  
Vol 16 (2) ◽  
pp. 77-83 ◽  
Author(s):  
TAKAFUMI YOSHIOKA ◽  
KENICHIROU INOMATA
Keyword(s):  
Spinal Cord ◽  
Alkaline Phosphatase ◽  
Adult Rats ◽  
Cytochemical Localization

scholarly journals Cytochemical localization of alkaline phosphatase and Na+-pump sites in adult rat colon.

1979 ◽  
Vol 27 (9) ◽  
pp. 1231-1235 ◽  
Author(s):  
P B Vengesa ◽  
U Hopfer
Keyword(s):  
Alkaline Phosphatase ◽  
Enzyme Activity ◽  
Electron Microscope ◽  
Colonic Mucosa ◽  
Brush Border Membrane ◽  
Rat Colon ◽  
Adult Rats ◽  
Cytochemical Localization ◽  
Chief Cells ◽  
Adult Rat

The cellular and subcellular locialization of alkaline and K+-dependent phosphatase activities in the colonic mucosa of adult rats and rabbits was studied with the electron microscope. The 1-cysteine-sensitive alkaline phosphatase activity was observed in the brush border membrane of the chief cells. The contraluminal plasma membrane of chief cells was devoid of this enzyme activity. In contrast, the cardiac glycoside-sensitive K+-dependent phosphatase was predominantly localized in this region of the cheif cells.

Support of axonal regrowth by endogenous mechanisms following spinal cord injury in adult rats

2001 ◽  
Vol 21 (3) ◽  
pp. 188-202 ◽  
Author(s):  
Norman R West ◽  
Victoria LeBlanc ◽  
George H Collins
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Adult Rats ◽  
Axonal Regrowth ◽  
Cord Injury

Serotonin2 receptors mediate respiratory recovery after cervical spinal cord hemisection in adult rats

2001 ◽  
Vol 91 (6) ◽  
pp. 2665-2673 ◽  
Author(s):  
Shi-Yi Zhou ◽  
Gregory J. Basura ◽  
Harry G. Goshgarian
Keyword(s):  
Spinal Cord ◽  
Receptor Antagonist ◽  
Phrenic Nerve ◽  
Cervical Spinal Cord ◽  
Sprague Dawley ◽  
Related Activity ◽  
Adult Rats ◽  
Cord Injury ◽  
Respiratory Recovery ◽  
Spinal Cord Hemisection

The aim of the present study was to specifically investigate the involvement of serotonin [5-hydroxytryptamine (5-HT2)] receptors in 5-HT-mediated respiratory recovery after cervical hemisection. Experiments were conducted on C2 spinal cord-hemisected, anesthetized (chloral hydrate, 400 mg/kg ip), vagotomized, pancuronium- paralyzed, and artificially ventilated female Sprague-Dawley rats in which CO2 levels were monitored and maintained. Twenty-four hours after spinal hemisection, the ipsilateral phrenic nerve displayed no respiratory-related activity indicative of a functionally complete hemisection. Intravenous administration of the 5-HT2A/2C-receptor agonist (±)-2,5-dimethoxy-4-iodoamphetamine hydrochloride (DOI) induced respiratory-related activity in the phrenic nerve ipsilateral to hemisection under conditions in which CO2 was maintained at constant levels and augmented the activity induced under conditions of hypercapnia. The effects of DOI were found to be dose dependent, and the recovery of activity could be maintained for up to 2 h after a single injection. DOI-induced recovery was attenuated by the 5-HT2-receptor antagonist ketanserin but not with the 5-HT2C-receptor antagonist RS-102221, suggesting that 5-HT2A and not necessarily 5-HT2C receptors may be involved in the induction of respiratory recovery after cervical spinal cord injury.

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