scholarly journals Diffusion-Weighted Magnetic Resonance Imaging of 103 Patients with Rectal Adenocarcinoma Identifies the Apparent Diffusion Coefficient as an Imaging Marker for Tumor Invasion and Regional Lymph Node Involvement

2021 ◽  
Vol 27 ◽  
Author(s):  
Jaromir Kargol ◽  
Wojciech Rudnicki ◽  
Jakub Kenig ◽  
Justyna Filipowska ◽  
Ewa Kaznowska ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Tumor Invasion ◽  
Regional Lymph Node ◽  
Rectal Adenocarcinoma ◽  
Lymph Node Involvement ◽  
Resonance Imaging ◽  
Regional Lymph Node Involvement ◽  
Apparent Diffusion ◽  
Node Involvement ◽  
Weighted Magnetic Resonance Imaging

scholarly journals Diffusion-weighted magnetic resonance imaging: biomarker for treatment response in oncology

2013 ◽  
Vol 46 (3) ◽  
pp. 178-180 ◽  
Author(s):  
Maria Luiza Testa ◽  
Rubens Chojniak ◽  
Letícia Silva Sene ◽  
Aline Santos Damascena
Keyword(s):  
Magnetic Resonance Imaging ◽  
Diffusion Coefficient ◽  
Quantitative Assessment ◽  
Therapeutic Response ◽  
Imaging Biomarker ◽  
Resonance Imaging ◽  
Adc Value ◽  
Early Increase ◽  
Apparent Diffusion ◽  
Weighted Magnetic Resonance Imaging

The authors report a case where a quantitative assessment of the apparent diffusion coefficient (ADC) of liver metastasis in a patient undergoing chemotherapy has shown to be an effective early marker for predicting therapeutic response, anticipating changes in tumor size. A lesion with lower initial ADC value and early increase in such value in the course of the treatment tends to present a better therapeutic response.

scholarly journals Transitional cell carcinoma of the urinary bladder with regional lymph node involvement treated by cystectomy

Cancer ◽  
2003 ◽  
Vol 97 (10) ◽  
pp. 2425-2431 ◽  
Author(s):  
Igor Frank ◽  
John C. Cheville ◽  
Michael L. Blute ◽  
Christine M. Lohse ◽  
Ajay Nehra ◽  
...  
Keyword(s):  
Lymph Node ◽  
Urinary Bladder ◽  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Regional Lymph Node ◽  
Transitional Cell ◽  
Lymph Node Involvement ◽  
Regional Lymph Node Involvement ◽  
Node Involvement

Evaluation of Extramural Venous Invasion by Diffusion-Weighted Magnetic Resonance Imaging and Computed Tomography in Rectal Adenocarcinoma

2019 ◽  
Vol 70 (4) ◽  
pp. 457-465 ◽  
Author(s):  
Aysegul Gursoy Coruh ◽  
Elif Peker ◽  
Atilla Elhan ◽  
Ilhan Erden ◽  
Ayse Erden
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Roc Analysis ◽  
Rectal Adenocarcinoma ◽  
Venous Invasion ◽  
Distant Metastases ◽  
Resonance Imaging ◽  
Adc Values ◽  
Weighted Magnetic Resonance Imaging

Purpose The aim of this study is to evaluate the diagnostic contribution of diffusion-weighted magnetic resonance imaging (MRI) and computed tomography (CT) to distinguish extramural venous invasion (EMVI) in rectal adenocarcinoma. Materials and Methods Fifty-eight patients who had been diagnosed with rectal adenocarcinoma (30 patients with EMVI and 28 patients without EMVI) were enrolled in the study. Apparent diffusion coefficient (ADC) values of the tumour and the EMVI (+) vein, the lengths of the tumours were measured on MRI. The diameters of the superior rectal vein (SRV)-inferior mesenteric vein (IMV) and distant metastatic spread were evaluated on CT. The ability of these findings to detect EMVI was assessed using receiver operating characteristic (ROC) analysis. Pathology was accepted as the reference test for EMVI. Results Mean diameters of the SRV (4.9 ± 0.9 mm vs 3.7 ± 0.8 mm) and IMV (6.9 ± 0.8 mm vs 5.4 ± 0.9 mm) were significantly larger ( P < .001) and tumour ADC values were significantly lower (0.926 ± 0.281 × 10−3 mm2/s vs 1.026 ± 0.246 × 10−3 mm2/s; P = .032) in EMVI (+) patients. Diameters of 3.95 mm for the SRV (area under the curve [AUC] ± standard error [SE]: 0.851 ± 0.051, P < .001, sensitivity: 93.3%, specificity: 67.9%) and 5.95 mm for the IMV (AUC ± SE: 0.893 ± 0.040, P < .001, sensitivity: 93.3%, specificity: 71.4%) and an ADC value of 0.929 × 10−3 mm2/s (AUC ± SE: 0.664 ± 0.072, P = .032 sensitivity: 76.7%, specificity: 57.1%) were found to be cutoff values, determined by ROC analysis, for detection of EMVI. Distant metastases were significantly more prevalent in EMVI (+) patients ( P < .001). Conclusion The measurement of ADC values and SRV-IMV diameters seems to have contribution for diagnosis of EMVI in rectal adenocarcinoma. EMVI (+) patients appear to have higher risks of distant metastases at diagnosis.

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