scholarly journals Upregulation of Neural Cell Adhesion Molecule 1 (NCAM1) by hsa-miR-141-3p Suppresses Ameloblastoma Cell Migration

2020 ◽  
Vol 26 ◽  
Author(s):  
Gengyao Guan ◽  
Xing Niu ◽  
Xue Qiao ◽  
Xiaobin Wang ◽  
Jinwen Liu ◽  
...  
Keyword(s):  
Cell Migration ◽  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Neural Cell Adhesion Molecule ◽  
Neural Cell ◽  
Neural Cell Adhesion ◽  
Cell Adhesion Molecule 1

scholarly journals Evolutionary conserved role of neural cell adhesion molecule-1 in memory

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Vanja Vukojevic ◽  
Pavlina Mastrandreas ◽  
Andreas Arnold ◽  
Fabian Peter ◽  
Iris-T. Kolassa ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Neural Cell Adhesion Molecule ◽  
Neural Cell ◽  
Neural Cell Adhesion ◽  
Cell Adhesion Molecule 1

scholarly journals Functional N-methyl-D-aspartate receptors in O-2A glial precursor cells: a critical role in regulating polysialic acid-neural cell adhesion molecule expression and cell migration.

1996 ◽  
Vol 135 (6) ◽  
pp. 1565-1581 ◽  
Author(s):  
C Wang ◽  
W F Pralong ◽  
M F Schulz ◽  
G Rougon ◽  
J M Aubry ◽  
...  
Keyword(s):  
Cell Migration ◽  
Cell Adhesion ◽  
Nmda Receptor ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Neural Cell Adhesion Molecule ◽  
Polysialic Acid ◽  
Neural Cell ◽  
Adhesion Molecule Expression ◽  
Neural Cell Adhesion

The capacity for long-distance migration of the oligodendrocyte precursor cell, oligodendrocyte-type 2 astrocyte (O-2A), is essential for myelin formation. To study the molecular mechanisms that control this process, we used an in vitro migration assay that uses neurohypophysial explants. We provide evidence that O-2A cells in these preparations express functional N-methyl-D-aspartate (NMDA) receptors, most likely as homomeric complexes of the NR1 subunit. We show that NMDA evokes an increase in cytosolic Ca2+ that can be blocked by the NMDA receptor antagonist AP-5 and by Mg2+. Blocking the activity of these receptors dramatically diminished O-2A cell migration from explants. We also show that NMDA receptor activity is necessary for the expression by O-2A cells of the highly sialylated polysialic acid-neural cell adhesion molecule (PSA-NCAM) that is required for their migration. Thus, glutamate or glutamate receptor ligands may regulate O-2A cell migration by modulating expression of PSA-NCAM. These studies demonstrate how interactions between ionotropic receptors, intracellular signaling, and cell adhesion molecule expression influence cell surface properties, which in turn are critical determinants of cell migration.

scholarly journals The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis

PLoS ONE ◽  
2015 ◽  
Vol 10 (8) ◽  
pp. e0133741 ◽  
Author(s):  
Mohadeseh Mehrabian ◽  
Dylan Brethour ◽  
Hansen Wang ◽  
Zhengrui Xi ◽  
Ekaterina Rogaeva ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Prion Protein ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Neural Cell Adhesion Molecule ◽  
Neural Cell ◽  
Cellular Morphogenesis ◽  
Neural Cell Adhesion ◽  
Cell Adhesion Molecule 1

NEURAL CELL ADHESION MOLECULE 1 (NCAM-1) IS ASSOCIATED TO LONG-TERM AVERSIVE MEMORY IN NEMATODES AND HUMANS

2019 ◽  
Vol 29 ◽  
pp. S852
Author(s):  
Vanja Vukojevic ◽  
Pavlina Mastrandreas ◽  
Virginie Freytag ◽  
Thomas Elbert ◽  
Iris Kolassa ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Neural Cell Adhesion Molecule ◽  
Neural Cell ◽  
Neural Cell Adhesion ◽  
Cell Adhesion Molecule 1

scholarly journals SNPs in the neural cell adhesion molecule 1 gene (NCAM1) may be associated with human neural tube defects

2005 ◽  
Vol 117 (2-3) ◽  
pp. 133-142 ◽  
Author(s):  
Kristen L. Deak ◽  
Abee L. Boyles ◽  
Heather C. Etchevers ◽  
Elizabeth C. Melvin ◽  
Deborah G. Siegel ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
Cell Adhesion Molecule ◽  
Neural Cell Adhesion Molecule ◽  
Neural Cell ◽  
Neural Cell Adhesion ◽  
Cell Adhesion Molecule 1
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