scholarly journals Coexpression Analysis of the EZH2 Gene Using The Cancer Genome Atlas and Oncomine Databases Identifies Coexpressed Genes Involved in Biological Networks in Breast Cancer, Glioblastoma, and Prostate Cancer

2020 ◽  
Vol 26 ◽  
Author(s):  
Jin Zhu ◽  
Lu Jin ◽  
Aili Zhang ◽  
Peng Gao ◽  
Guangcheng Dai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prostate Cancer ◽  
Biological Networks ◽  
Cancer Genome ◽  
The Cancer Genome Atlas ◽  
Coexpression Analysis ◽  
Cancer Genome Atlas ◽  
Coexpressed Genes ◽  
Genome Atlas

scholarly journals The construction and analysis of ceRNA networks in invasive breast cancer: a study based on The Cancer Genome Atlas

2018 ◽  
Vol Volume 11 ◽  
pp. 1-11 ◽  
Author(s):  
Chundi Gao ◽  
Huayao Li ◽  
Jing Zhuang ◽  
HongXiu Zhang ◽  
Kejia Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Invasive Breast Cancer ◽  
Cancer Genome ◽  
The Cancer Genome Atlas ◽  
Cancer Genome Atlas ◽  
Genome Atlas

Using machine learning method to identify MYLK as a novel marker to predict biochemical recurrence in prostate cancer

2021 ◽  
Vol 15 (1) ◽  
pp. 29-41
Author(s):  
Peng Qiao ◽  
Di Zhang ◽  
Song Zeng ◽  
Yicun Wang ◽  
Biao Wang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Prostate Cancer ◽  
Biochemical Recurrence ◽  
Surgical Margin ◽  
Gene Expression Omnibus ◽  
Cancer Genome ◽  
The Cancer Genome Atlas ◽  
Support Vector ◽  
Cancer Genome Atlas ◽  
Genome Atlas

Aim: This study aims to identify novel marker to predict biochemical recurrence (BCR) in prostate cancer patients after radical prostatectomy with negative surgical margin. Materials & methods: The Cancer Genome Atlas database, Gene Expression Omnibus database and Cancer Cell Line Encyclopedia database were employed. The ensemble support vector machine-recursive feature elimination method was performed to select crucial gene for BCR. Results: We identified MYLK as a novel and independent biomarker for BCR in The Cancer Genome Atlas training cohort and confirmed in four independent Gene Expression Omnibus validation cohorts. Multi-omic analysis suggested that MYLK was a DNA methylation-driven gene. Additionally, MYLK had significant positive correlations with immune infiltrations. Conclusion: MYLK was identified and validated as a novel, robust and independent biomarker for BCR in prostate cancer.

scholarly journals Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

JAMA Oncology ◽  
2017 ◽  
Vol 3 (12) ◽  
pp. 1654 ◽  
Author(s):  
Dezheng Huo ◽  
Hai Hu ◽  
Suhn K. Rhie ◽  
Eric R. Gamazon ◽  
Andrew D. Cherniack ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Genome ◽  
The Cancer Genome Atlas ◽  
European Ancestry ◽  
Molecular Features ◽  
Cancer Genome Atlas ◽  
Genome Atlas

scholarly journals MP04-16 CLINICAL ASSOCIATIONS WITH PROSTATE CANCER MOLECULAR FEATURES IN THE CANCER GENOME ATLAS (TCGA) DATA.

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Daniel Lee ◽  
David Golombos ◽  
Padraic O'Malley ◽  
Deli Liu ◽  
Andrea Sboner ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Genome ◽  
The Cancer Genome Atlas ◽  
Molecular Features ◽  
Cancer Genome Atlas ◽  
Clinical Associations ◽  
Genome Atlas
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