scholarly journals Comparison of Real-Time Two-Dimensional and Three-Dimensional Contrast-Enhanced Ultrasound to Quantify Flow in an In Vitro Model: A Feasibility Study

2019 ◽  
Vol 25 ◽  
pp. 10029-10035
Author(s):  
Si-Min Ruan ◽  
Qiao Zheng ◽  
Zhu Wang ◽  
Hang-Tong Hu ◽  
Li-Da Chen ◽  
...  
Keyword(s):  
Real Time ◽  
Feasibility Study ◽  
In Vitro Model ◽  
Three Dimensional ◽  
Two Dimensional ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Vitro Model

Biotransformations and cytotoxicity of graphene and inorganic two-dimensional nanomaterials using simulated digestions coupled with a triculture in vitro model of the human gastrointestinal epithelium

2021 ◽  
Author(s):  
Lila Bazina ◽  
Dimitrios Bitounis ◽  
Xiaoqiong Cao ◽  
Glen M. DeLoid ◽  
Dorsa Parviz ◽  
...  
Keyword(s):  
In Vitro Model ◽  
Engineered Nanomaterials ◽  
Two Dimensional ◽  
Gastrointestinal Epithelium ◽  
Vitro Model ◽  
Human Gastrointestinal Epithelium

Background: engineered nanomaterials (ENMs) have already made their way into myriad applications and products across multiple industries.

scholarly journals Skeletal muscle-on-a-chip: an in vitro model to evaluate tissue formation and injury

Lab on a Chip ◽  
2017 ◽  
Vol 17 (20) ◽  
pp. 3447-3461 ◽  
Author(s):  
Gaurav Agrawal ◽  
Aereas Aung ◽  
Shyni Varghese
Keyword(s):  
Skeletal Muscle ◽  
Muscle Injury ◽  
In Vitro Model ◽  
Three Dimensional ◽  
Tissue Formation ◽  
Microfluidic Platform ◽  
Muscle Tissues ◽  
Vitro Model

We introduce a microfluidic platform in which we culture three-dimensional skeletal muscle tissues, while evaluating tissue formation and toxin-induced muscle injury.

scholarly journals A New 3D Cultured Liver Chip and Real-Time Monitoring System Based on Microfluidic Technology

Micromachines ◽  
2020 ◽  
Vol 11 (12) ◽  
pp. 1118
Author(s):  
Yao Zhang ◽  
Ning Yang ◽  
Liangliang Xie ◽  
Fangyu Shu ◽  
Qian Shi ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Real Time ◽  
Monitoring System ◽  
Near Infrared Spectroscopy ◽  
In Vitro Model ◽  
Near Infrared ◽  
Real Time Monitoring ◽  
Microfluidic Technology ◽  
Vitro Model

In vitro models of the liver have a good simulation of the micro-liquid environment inside the human liver and the communication between cell tissues, which provides an important research tool for drug research and liver disease treatment. In this paper, we designed a 3D liver chip and real-time monitoring system based on microfluidic technology. The in vitro model of the liver on the chip was established by the three-dimensional microfluidic chip pipeline and the corresponding microwell array. Meanwhile, the culture medium is continuously injected on the chip, and the electrochemical impedance spectroscopy and near-infrared spectroscopy of the liver chip are recorded and analyzed from day one to day five. When the 3D cultured liver chip in vitro model reached a certain period and stabilized, paracetamol with varying gradients of concentration was applied to the cultured cells for drug resistance testing. The experimental results show that the liver chip and its monitoring system designed in this paper can maintain 100% cell viability of hepatocytes in vitro for a long time. Furthermore, it can meet the requirements of measurement technologies such as electrical impedance measurement and near-infrared spectroscopy in real-time, providing a stable culture platform for the further study of organ chips.

scholarly journals A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes

Leukemia ◽  
2019 ◽  
Vol 34 (1) ◽  
pp. 271-282 ◽  
Author(s):  
Edda María Elvarsdóttir ◽  
Teresa Mortera-Blanco ◽  
Marios Dimitriou ◽  
Thibault Bouderlique ◽  
Monika Jansson ◽  
...  
Keyword(s):  
Myelodysplastic Syndromes ◽  
In Vitro Model ◽  
Three Dimensional ◽  
Vitro Model
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