scholarly journals Skin Prick Testing to Identify Food Allergens in 8393 Children and Adolescents with Asthma in Chongqing, Southwest China

2019 ◽  
Vol 25 ◽  
pp. 8221-8229 ◽  
Author(s):  
Rong Guo ◽  
Ling Wang ◽  
Xiao-Ping Yuan ◽  
Ping Sun
2021 ◽  
Author(s):  
fanyan du ◽  
lin mo

Abstract Background: Osteogenesis imperfecta(OI)is a chronic, non-infectious disease that accompanies the patient for life. OI will result in reduced bone mass, fractures, thereby leading to bone deformities and reduced patient the health-related quality of life (HRQoL). With the endocrine therapy and surgical orthopedic had been recommended, the disease was effectively controlled. The disease status is discrepancy in different regions. This study aims to assess the diagnosis and treatment status, evaluate the HRQoL of children and adolescents with OI in southwest China, and analyze the influencing factors, so as to provide reference for health care consideration for OI population in southwest China.Methods: This cross-sectional study was performed using the Pediatric Quality of Life InventoryTM (PedsQL TM) to assess the HRQoL of children and adolescents with OI. The demographic and clinical data were collected. This study was conducted in Children’s Hospital of Chongqing Medical University, the National Children's Regional Medical Centre (SOUTH-WEST) and the National Clinical Research for child health. Healthy children and adolescents aged 2 to 18 years lived in southwest China as a reference.Results: A total of 27 children and adolescents with OI were included in this study. The current status of diagnosis and treatment such as the treatment, education, family, BMI, pain, steep walking and friends and so on had been investigated. The PedsQLTM of OI population was lower in all dimensions, and they were significantly different in physiological and social functioning and the total score, compared with 54 healthy children and adolescents. Factors associated with HRQoL of OI patients were the steep walking and fixing a playmate at less.Conclusions: The HRQoL of children and adolescents with OI had been improved with the endocrine therapy and surgical orthopedic. But there was an imbalance around the world for the less effective management. Health care education should be more professional, effectively and continuously. Training patients to gain steep walking ability and peer companionship could be a way to improve the HRQoL of children and adolescents with OI in southwest China. The medical staff also should pay attention to their life and growth after discharge.


2021 ◽  
Vol 49 (5) ◽  
pp. 42-48
Author(s):  
Ana Carolina Rozalem-Reali ◽  
Felipe Faria Pierotti ◽  
Aranda Carolina ◽  
Renata Rodrigues Cocco ◽  
Emanuel Cavalcanti Sarinho ◽  
...  

The Phadiatop Infant® (PhInf) is a panel developed to assess allergic sensitization (immunoglobulin E [IgE]) in children aged <5 years and combines inhalant and food allergens. The test has not been evaluated outside Europe. This is a cross-sectional study conducted at 11 pediatric allergy centers to evaluate PhInf as an allergic disease screening method in Brazilian children. Children as controls and patients (aged 6 months–18 years) were grouped according to their primary disease and age group. PhInf and specific serum IgE (sIgE) screening was performed for Dermatophagoides pteronyssinus (DP), cat and dog epithelia, a mix of grasses and pollens, eggs, cow’s milk, peanuts, and shrimp. Values ≥ 0.35 kUA/L (or PAU/L) were considered positive. A total of 470 children and adolescents, which included 385 patients and 85 controls, participated in the study (47.7% boys, average age: 6.3 years). In all, 72.6% of the participants had positive PhInf test (n = 341), with a higher proportion of those having food allergy (92.6%), atopic dermatitis (91.9%), and those aged >13 years having allergy (95%). The PhInf and sIgE agreement between patients (Kappa = 0.94, P < 0.001) and controls (Kappa = 0.84, P < 0.001) was high. PhInf and DP agreement in patients aged >13 years was excellent (Kappa = 0.936, P < 0.001). Compared with sIgE dosage, PhInf had high sensitivity (97%) and specificity (93%). Positivity of PhInf test in this population was high and had an excellent correlation with the allergens comprising the panel. It is a useful method for screening children suspected of having allergic diseases in a non-European country.


2011 ◽  
Vol 157 (4) ◽  
pp. 391-398 ◽  
Author(s):  
Umit Murat Şahiner ◽  
Ersoy Civelek ◽  
Süleyman Tolga Yavuz ◽  
Ayşe Betül Büyüktiryaki ◽  
Ayfer Tuncer ◽  
...  

2021 ◽  
Vol 10 (4) ◽  
pp. 65-69
Author(s):  
Rebecca Yingxue Qin ◽  
Suganya Vignakaran ◽  
Taren Bettler ◽  
Sarah Mulqueeny ◽  
David Espinoza ◽  
...  

2021 ◽  
Vol 100 (2) ◽  
pp. 72-77
Author(s):  
N.V. Shakhova ◽  
◽  
E.M. Kamaltynova ◽  
T.S. Kashinskaya ◽  
◽  
...  

The aim of the trial was to study the prevalence and clinical and allergic characteristics of allergic rhinitis (AR) and bronchial asthma (BA) in urban preschool children. Materials and methods of research: a one-minute study was carried out on an urban sample of 3–6 year olds (n=3205), consisting of 2 stages – screening and clinical. The study of the prevalence of AR and BA symptoms at the screening stage was carried out by questioning parents using the ISAAC questionnaire. At the clinical stage, the diagnosis of AR and BA was verified based on the diagnostic criteria of the ARIA (2008 revision) and GINA (updated 2017) documents. At the clinical stage, skin prick testing with extracts of inhalation and food allergens from Allergopharma Joachim Ganzer KG (Germany) was carried out. Results: the prevalence of AR and BA among urban children 3–6 years of age was 10,6 and 5,7%, respectively. 80 (52,0%) children with AR and 42 (32,8%) children with BA have not previously been diagnosed in practical healthcare institutions. 107 (69,5%) children with AR and 76 (59,4%) children with BA had a mild severity of the disease, 4 (2,6%) children with AR and 2 (1,6%) children with BA had major severity. 80 (62,5%) of children with BA are diagnosed with a controlled course of the disease and 48 (37,5%) have a partially controlled/uncontrolled course of the disease. Most often, in children with AR and BA, sensitization to the D. pteronyssinus mite was recorded – 95 (61,%) and 68 (53,1%), birch pollen – 63 (40,9%) and 42 (32,8%) and cat allergens – 30 (19,5%) and 20 (15,6%), respectively. Conclusion: the prevalence of AR and BA among preschool children was 10,6 and 5,7%, respectively. More than half of children with AR and 1/3 of children with BA do not have a diagnosis established in practical health care institutions. Most often, in 3–6 years old children with AR and BA, sensitization to the D. pteronyssinus mite, birch pollen and cat allergens is recorded.


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