scholarly journals Association of Intracranial Artery Calcification with Cognitive Impairment in Hemodialysis Patients

2019 ◽  
Vol 25 ◽  
pp. 5036-5043 ◽  
Author(s):  
Nam-Jun Cho ◽  
Samel Park ◽  
Eun-young Lee ◽  
Se Won Oh ◽  
Hyung Geun Oh ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Hemodialysis Patients ◽  
Intracranial Artery ◽  
Intracranial Artery Calcification

Prevalence of intracranial artery calcification in hemodialysis patients—a case–control study

2011 ◽  
Vol 44 (4) ◽  
pp. 1223-1228 ◽  
Author(s):  
Yuko Iwasa ◽  
Shigeru Otsubo ◽  
Kazuomi Nomoto ◽  
Naobumi Yashiro ◽  
Aiji Yajima ◽  
...  
Keyword(s):  
Case Control Study ◽  
Hemodialysis Patients ◽  
Case Control ◽  
Intracranial Artery ◽  
Intracranial Artery Calcification ◽  
Control Study

Intracranial artery calcification in hemodialysis patients

2009 ◽  
Vol 43 (2) ◽  
pp. 585-588 ◽  
Author(s):  
Yuko Iwasa ◽  
Shigeru Otsubo ◽  
Aiji Yajima ◽  
Naoki Kimata ◽  
Takashi Akiba ◽  
...  
Keyword(s):  
Hemodialysis Patients ◽  
Intracranial Artery ◽  
Intracranial Artery Calcification

Depression and Cognitive Impairment in Patients on Hemodialysis: A cross-sectional study

2020 ◽  
Vol 5 (15) ◽  
pp. 185-192
Author(s):  
Nor Jannah Nasution Raduan ◽  
Mohd Razali Salleh ◽  
Ghazali Ahmad ◽  
Zaleha Ismail
Keyword(s):  
Cognitive Impairment ◽  
Publishing House ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Education Level ◽  
Sectional Study ◽  
Contributing Factors ◽  
Cross Sectional ◽  
Factors Associated ◽  
Low Education

Depression and cognitive impairment are the most common complications of patients on hemodialysis. The objective of this study is to identify contributing factors to depression and cognitive impairment in hemodialysis patients. This is a cross-sectional study involving 110 hemodialysis patients in Hospital Kuala Lumpur. The samples were recruited through universal sampling. Patients were assessed with the Beck Depression Inventory and Montreal Cognitive Assessment. This study found that 18.2% of patients had depression, and 48.2% had cognitive impairment. Factors associated with depression were unmarried status, low education level, and cognitive impairment. Factors associated with cognitive impairment were low education level, depression, and unemployment. Keywords: hemodialysis, depression, cognitive, ESRD eISSN: 2398-4287© 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v5i15.2468.

scholarly journals Intradialytic Cerebral Hypoperfusion as Mechanism for Cognitive Impairment in Patients on Hemodialysis

2019 ◽  
Vol 30 (11) ◽  
pp. 2052-2058 ◽  
Author(s):  
Dawn F. Wolfgram
Keyword(s):  
Cognitive Impairment ◽  
Cerebral Perfusion ◽  
Ischemic Injury ◽  
Hemodialysis Patients ◽  
Cognitive Outcomes ◽  
Cerebral Injury ◽  
Cerebral Hypoperfusion ◽  
Increased Risk ◽  
Cerebral Ischemic Injury ◽  
Cerebral Ischemic

The high frequency of cognitive impairment in individuals on hemodialysis is well characterized. In-center hemodialysis patients are disproportionately affected by cognitive impairment compared with other dialysis populations, identifying hemodialysis itself as a possible factor. The pathophysiology of cognitive impairment has multiple components, but vascular-mediated cerebral injury appears to contribute based on studies demonstrating increased cerebral ischemic lesions and atrophy in brain imaging of patients on hemodialysis. Patients on hemodialysis may be at increased risk for cerebral ischemic injury disease due to vasculopathy associated with ESKD and from their comorbid diseases, such as hypertension and diabetes. This review focuses on the intradialytic cerebral hypoperfusion that can occur during routine hemodialysis due to the circulatory stress of hemodialysis. This includes a review of current methods used to monitor intradialytic cerebral perfusion and the structural and functional cognitive outcomes that have been associated with changes in intradialytic cerebral perfusion. Monitoring of intradialytic cerebral perfusion may become clinically relevant as nephrologists try to avoid the cognitive complications seen with hemodialysis. Identifying the appropriate methods to assess risk for cerebral ischemic injury and the relationship of intradialytic cerebral hypoperfusion to cognitive outcomes will help inform the decision to use intradialytic cerebral perfusion monitoring in the clinical setting as part of a strategy to prevent cognitive decline.

scholarly journals Postmortem Study Exploring Distribution and Patterns of Intracranial Artery Calcification

Stroke ◽  
2018 ◽  
Vol 49 (11) ◽  
pp. 2767-2769 ◽  
Author(s):  
Wen-Jie Yang ◽  
Lu Zheng ◽  
Xiao-Hong Wu ◽  
Zhong-Qing Huang ◽  
Chun-Bo Niu ◽  
...  
Keyword(s):  
Intracranial Artery ◽  
Postmortem Study ◽  
Intracranial Artery Calcification

scholarly journals Prevalence and patterns of cognitive impairment in adult hemodialysis patients: the COGNITIVE-HD study

2017 ◽  
Vol 33 (7) ◽  
pp. 1197-1206 ◽  
Author(s):  
Anita van Zwieten ◽  
Germaine Wong ◽  
Marinella Ruospo ◽  
Suetonia C Palmer ◽  
Maria Rosaria Barulli ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Hemodialysis Patients

scholarly journals Harnessing Digital Health to Objectively Assess Cognitive Impairment in People undergoing Hemodialysis Process: The Impact of Cognitive Impairment on Mobility Performance Measured by Wearables

2019 ◽  
Author(s):  
He Zhou ◽  
Fadwa Al-Ali ◽  
Changhong Wang ◽  
Abdullah Hamad ◽  
Rania Ibrahim ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Performance Metrics ◽  
Digital Health ◽  
Hemodialysis Patients ◽  
Intact Group ◽  
Mobility Performance ◽  
Walking Performance ◽  
Task Conditions ◽  
Additional Value ◽  
The Impact

AbstractBackgroundCognitive impairment is prevalent but still poorly diagnosed in hemodialysis adults, mainly because of the impracticality of current tools. This study examined whether remotely monitoring mobility performance can help identifying digital measures of cognitive impairment in hemodialysis patients.MethodsSixty-nine hemodialysis patients (age=64.1±8.1years, body mass index=31.7±7.6kg/m2) were recruited. According to the Mini-Mental State Exam, 44 (64%) were determined as cognitive-intact, and 25 (36%) as cognitive-impaired. Mobility performance, including cumulated posture duration (sitting, lying, standing, and walking), daily walking performance (step and unbroken walking bout), as well as postural-transition (daily number and average duration), were measured using a validated pendant-sensor for a continuous period of 24-hour during a non-dialysis day. Motor capacity was quantified by assessing standing balance and gait performance under single-task and dual-task conditions.ResultsNo between-group difference was observed for the motor capacity. However, the mobility performance was different between groups. The cognitive-impaired group spent significantly higher percentage of time in sitting and lying (Cohens effect size d=0.78, p=0.005) but took significantly less daily steps (d=0.69, p=0.015) than the cognitive-intact group. The largest effect of reduction in number of postural-transition was observed in walk-to-sit transition (d=0.65, p=0.020). Regression models based on demographics, addition of daily walking performance, and addition of other mobility performance metrics, led to area-under-curves of 0.76, 0.78, and 0.93, respectively, for discriminating cognitive-impaired cases.ConclusionsThis study suggests that mobility performance metrics could be served as potential digital biomarkers of cognitive impairment among HD patients. It also highlights the additional value of measuring cumulated posture duration and postural-transition to improve the detection of cognitive impairment. Future studies need to examine potential benefits of mobility performance metrics for early diagnosis of cognitive impairment/dementia and timely intervention.

scholarly journals THE RELATIONSHIP BETWEEN FRAILTY AND COGNITIVE IMPAIRMENT IN YOUNG ADULT HEMODIALYSIS PATIENTS

2019 ◽  
Vol 82 (2) ◽  
Author(s):  
Ertuğrul Erken ◽  
Gülsüm Akkuş ◽  
Fatma Betül Güzel ◽  
Neziha Ulusoylar ◽  
Orçun Altınören ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Young Adult ◽  
Hemodialysis Patients ◽  
The Relationship

scholarly journals P1501KIDNEY FAILURE AND BRAIN FUNCTION DECLINE

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Clara Pardinhas ◽  
Carolina Figueiredo ◽  
Alice Lança ◽  
Helena Pinto ◽  
Helena Sá ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Clinical Characteristics ◽  
Hemodialysis Patients ◽  
Cerebral Hypoperfusion ◽  
Recent Analysis ◽  
Major Health ◽  
Significance Level ◽  
History Of ◽  
Prognostic Implications ◽  
State Examination

Abstract Background and Aims: Chronic kidney disease (CKD) and cognitive impairment (CI) are two major health problems in an aging population, and both carry out negative prognostic implications. Prevalence in general population appears to be around 22.2% and recent analysis indicates that CI and frailty can be more prevalent in individuals undergoing hemodialysis (HD). Many causes can contribute to this higher prevalence, from vascular calcification to cerebral hypoperfusion, oxidative damage and uremic toxins. Both frailty and CI can lead to an increase morbimortality. Montreal Cognitive Assessment (MoCA) and Mini Mental State Examination (MMSE) are two screening instruments with a good application profile for cognitive evaluation, as well as the Frailty Clinical Scale (FCS). However, there are few studies using these scales on HD patients and demonstrating association between frailty, cognitive impairment and their clinical characteristics. The aim of this study is to investigate the prevalence of coexisting cognitive impairment and frailty in our center hemodialysis patients and its association with clinical characteristics and outcomes. Method: Thirty-two patients undergoing hospital hemodialysis program were assessed. The MoCA scale, MMSE and FCS were applied. Data were analyzed using appropriate statistical methods, using SPSS ® version 22.0. The significance level considered was 5%. Results: Thirty-two patients aged between 30 and 90 years were evaluated, with a mean of 61.63 years (SD ± 18.26), without gender predominance. The prevalence of deficits was 78.1% and 37,5% in MoCA and MMSE, respectively, without differences between gender. The prevalence of frailty (≥3) was 43.8%. Patients with deficit assessed by MoCA and MMSE were on average 15 years and 20 years older, respectively, than patients without deficit (p = 0.002). We found a statistically significant association between deficit measured by MMSE and frailty (p <.001), with higher prevalence of frailty (83.3%) in individuals with deficit compared to individuals without deficit, where the prevalence of frailty was 20.0%. The deficit assessed by MMSE was also associated with time on dialysis (p = .029). No statistically significant associations were detected between MoCA and frailty over time on dialysis or between deficit measured by MoCA and frailty. Regarding patients’ comorbidities, there were no statistically significant differences between deficit assessed by MoCA and MMSE and presence of diabetes mellitus, hypertension and dyslipidemia. Deficits assessed by MoCA, MMSE, and Frailty were not associated with phosphoremia and also there was no association between presence of significative hypotension episodes during HD and these scales. Dialysis efficacy (kt/v) was not statistically associated with MoCA and MMSE deficits. Similarly, no association was found between Kt / v and frailty. Conclusion: In our study, prevalence of CI and frailty in hemodialysis patients was high. Time on dialysis program was related in a statistically significant way with CI and there was higher prevalence of frailty in individuals with deficit measured by MMSE. However, we did not find a correlation between dialysis efficacy, comorbidities and vascular risk factors and cognitive deficit or frailty score. The epidemiology and natural history of cognitive impairment and its association with frailty are important to understand among patients on HD for early intervention and management.

Sign in / Sign up

Export Citation Format

Share Document