scholarly journals Effect of Dome-Shaped Titanium Mesh Cages on Cervical Endplate Under Cyclic Loading: An In Vitro Biomechanics Study

2019 ◽  
Vol 25 ◽  
pp. 142-149
Author(s):  
Yibin Wang ◽  
Teng Lu ◽  
Xijing He ◽  
Zhijing Wen ◽  
Zhengchao Gao ◽  
...  
Keyword(s):  
Cyclic Loading ◽  
Titanium Mesh ◽  
In Vitro Biomechanics

scholarly journals Impact of Different Screw Designs on Durability of Fracture Fixation: In Vitro Study with Cyclic Loading of Scaphoid Bones

PLoS ONE ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. e0145949 ◽  
Author(s):  
Dominik Gruszka ◽  
Robert Herr ◽  
Hans Hely ◽  
Peer Hofmann ◽  
Daniela Klitscher ◽  
...  
Keyword(s):  
Cyclic Loading ◽  
Fracture Fixation ◽  
In Vitro Study ◽  
Vitro Study

In Vitro Stain Transport in Canaliculi of Rat Femora Under Cyclic Loading

2000 ◽  
Author(s):  
Bixia Li ◽  
Timothy L. Norman
Keyword(s):  
Fluid Flow ◽  
Cyclic Loading ◽  
Confocal Microscopy ◽  
Mechanical Loading ◽  
Cyclic Load ◽  
Flow Behavior ◽  
Load Level ◽  
Static Conditions ◽  
Rat Bone

Abstract In this study, rat femurs were used to test the diffusion and mechanical transport properties of a fluroscein stain tracer in microvessels of bone. Fluroscein was used as a tracer to visualize the fluid flow behavior using confocal microscopy. It was found that stain transport occurs due to diffusion under static conditions and due to mechanical loading. The transport increased with cyclic load level and frequency. Our results also show that stain transport at the canaliculi level occurs rapidly in rat bone.

Influence of Cyclic Loading on Mechanical Loosening of Hinged Knee Prostheses

1978 ◽  
Vol 7 (4) ◽  
pp. 235-239 ◽  
Author(s):  
D. H. van Campen ◽  
H. W. Croon ◽  
J. Lindwer
Keyword(s):  
Experimental Investigation ◽  
Cyclic Loading ◽  
Mechanical Loading ◽  
Knee Prosthesis ◽  
In Vitro Experiments ◽  
Knee Prostheses ◽  
Normal Walking ◽  
Fresh Cadaver ◽  
Unfavourable Effect

A combined theoretical and experimental investigation is reported with respect to the influence of mechanical loading on loosening at the cement bone interface of knee prostheses with intermedullary stems. The in vitro experiments have been performed under cyclic loading conditions with the tibial part of a Shiers knee prosthesis implanted in fresh cadaver tibiae. The experimental results indicate an unfavourable effect of peak loading (as occurring in walking up stairs) on loosening as compared with loading due to normal walking conditions.

Mechanical loading regulates NOS expression and activity in developing and adult skeletal muscle

1998 ◽  
Vol 275 (1) ◽  
pp. C260-C266 ◽  
Author(s):  
James G. Tidball ◽  
Eliane Lavergne ◽  
Kim S. Lau ◽  
Melissa J. Spencer ◽  
James T. Stull ◽  
...  
Keyword(s):  
Cyclic Loading ◽  
Muscle Activation ◽  
Weight Bearing ◽  
No Production ◽  
Adult Skeletal Muscle ◽  
No Release ◽  
Cultured Myotubes ◽  
Passive Stretch ◽  
Expression And Activity

The hypothesis that changes in muscle activation and loading regulate the expression and activity of neuronal nitric oxide (NO) synthase (nNOS) was tested using in vitro and in vivo approaches. Removal of weight bearing from rat hindlimb muscles for 10 days resulted in a significant decrease in nNOS protein and mRNA concentration in soleus muscles, which returned to control concentrations after return to weight bearing. Similarly, the concentration of nNOS in cultured myotubes increased by application of cyclic loading for 2 days. NO release from excised soleus muscles was increased significantly by a single passive stretch of 20% or by submaximal activation at 2 Hz, although the increases were not additive when both stimuli were applied simultaneously. Increased NO release resulting from passive stretch or activation was dependent on the presence of extracellular calcium. Cyclic loading of cultured myotubes also resulted in a significant increase in NO release. Together, these findings show that activity of muscle influences NO production in the short term, by regulating NOS activity, and in the long term, by regulating nNOS expression.

scholarly journals In vitro evaluation of the tension band suture method for proximal humerus fracture treatment

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Hideaki Ishii ◽  
Takanori Shintaku ◽  
Shu Yoshizawa ◽  
Misato Sakamoto ◽  
Takao Kaneko ◽  
...  
Keyword(s):  
Cyclic Loading ◽  
Proximal Humerus Fracture ◽  
Tension Band ◽  
Proximal Humeral Fractures ◽  
Humeral Fractures ◽  
Suture Materials ◽  
Loading Test ◽  
Cyclic Loading Test ◽  
Mechanical Durability

Abstract Background Proximal humeral fractures are common, and more than half occur in patients over 65 years of age. Operative treatment may be recommended for displaced, complicated fractures; however, surgery may lead to displacement of the greater tuberosity or humeral head. Supplemental tension band sutures have been recommended to prevent such a complication. In this study, we investigate the best combination of suture, washer, and threading angle for proximal humeral fractures from a mechanical view. Methods The mechanical durability of 18 combinations of suture materials (Fiberwire, Ethibond, and Surgilon), threading washers (ring washer, disc washer), and threading angles (15 or 45°) were examined via a cyclic loading test. Results The most durable combination in the cyclic loading test consisted of threading the Fiber Wire to the washer ring using only one hole (ring washer-1) at 45°. In contrast, the most vulnerable combination was threading Ethibond to the washer disc at 15°. Breakage of all suture materials occurred at the suture-washer interface, and no failure or loosening of the knots was observed. FiberWire gradually eroded until the loss of equilibrium; whereas the rupture of Ethibond and Surgilon occurred suddenly. Conclusions From a mechanical viewpoint, we demonstrated that applying a supplemental tension band suture using FiberWire with a single-hole ring washer threaded at a wider angle is recommended.

In vitro biomechanics of the craniocervical junction—a sequential sectioning of its stabilizing structures

2015 ◽  
Vol 15 (7) ◽  
pp. 1618-1628 ◽  
Author(s):  
Kris E. Radcliff ◽  
Mir M. Hussain ◽  
Mark Moldavsky ◽  
Noelle Klocke ◽  
Alexander R. Vaccaro ◽  
...  
Keyword(s):  
Craniocervical Junction ◽  
In Vitro Biomechanics

Crown retention and cyclic loading (in vitro)

1993 ◽  
Vol 101 (4) ◽  
pp. 252-256 ◽  
Author(s):  
Agneta Gundler ◽  
Paul Lockowandt ◽  
Svante Erhardson
Keyword(s):  
Cyclic Loading
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