scholarly journals miR-155-5p Promotes Progression of Acute Respiratory Distress Syndrome by Inhibiting Differentiation of Bone Marrow Mesenchymal Stem Cells to Alveolar Type II Epithelial Cells

2018 ◽  
Vol 24 ◽  
pp. 4330-4338 ◽  
Author(s):  
Jing Jiang ◽  
Zhifang Song ◽  
Lanyue Zhang
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Alveolar Type ◽  
Type Ii ◽  
Marrow Mesenchymal Stem Cells

scholarly journals The effect of acute respiratory distress syndrome on bone marrow-derived mesenchymal stem cells

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Ben Antebi ◽  
Kerfoot P. Walker ◽  
Arezoo Mohammadipoor ◽  
Luis A. Rodriguez ◽  
Robbie K. Montgomery ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome

scholarly journals Airway Delivery of Bone Marrow–Derived Mesenchymal Stem Cells Reverses Bronchopulmonary Dysplasia Superimposed with Acute Respiratory Distress Syndrome in an Infant

Cell Medicine ◽  
2018 ◽  
Vol 10 ◽  
pp. 215517901875943 ◽  
Author(s):  
Hsin-Chia Lin ◽  
Ching-Chia Wang ◽  
Heng-Wen Chou ◽  
En-Ting Wu ◽  
Frank Leigh Lu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Bronchopulmonary Dysplasia ◽  
Distress Syndrome ◽  
Bronchial Wash ◽  
Adenovirus Pneumonia

Bronchopulmonary dysplasia (BPD), a disease affecting extremely premature infants, results from the disruption of normal pulmonary vascular and alveolar growth. Currently, there is no specific effective treatment. We report a case of a 10-mo-old female infant with BPD, who was admitted because of adenovirus pneumonia and acute respiratory distress syndrome (ARDS) with prolonged venovenous and arteriovenous extracorporeal membrane oxygenation (ECMO) support (total 125 d). The respiratory condition dramatically improved, and ECMO was removed 25 d after intratracheal delivery of maternal bone marrow-derived mesenchymal stem cells (BM-MSCs). Short tandem repeat examinations revealed that there was no maternal cells in the bronchial wash fluid. To our knowledge, this is the first human report of BM-MSC therapy reversal of the course of BPD superimposed with ARDS. We also suggest that BM-MSC therapy may not only be effective in the newborn stage but also works in infants and children with BPD.

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