scholarly journals Overexpression of SET and MYND Domain-Containing Protein 2 (SMYD2) Is Associated with Tumor Progression and Poor Prognosis in Patients with Papillary Thyroid Carcinoma

2018 ◽  
Vol 24 ◽  
pp. 7357-7365 ◽  
Author(s):  
Wenchao Xu ◽  
Fulian Chen ◽  
Xiao Fei ◽  
Xiaoqing Yang ◽  
Xiaofei Lu
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Tumor Progression ◽  
Poor Prognosis ◽  
Papillary Thyroid

Overexpression of serum lncRNA-ABHD11-AS1 as poor prognosis of patients with papillary thyroid carcinoma

2021 ◽  
pp. 104658
Author(s):  
Sen Hou ◽  
Yu-Ying Zhuang ◽  
Qiu-Yu Lin ◽  
Zhen Chen ◽  
Hong-Guang Zhao ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Poor Prognosis ◽  
Papillary Thyroid

scholarly journals Should a family history of papillary thyroid carcinoma indicate more aggressive therapy in patients with this tumor?

2014 ◽  
Vol 58 (8) ◽  
pp. 812-816 ◽  
Author(s):  
Pedro Weslley Rosario ◽  
Maria Regina Calsolari
Keyword(s):  
Lymph Node ◽  
Family History ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Lymph Node Dissection ◽  
Poor Prognosis ◽  
Tumor Resection ◽  
Papillary Thyroid ◽  
Node Dissection ◽  
History Of

Objective To determine whether the currently recommended therapy for papillary thyroid carcinoma (PTC) that show no classical factors indicating a poor prognosis is also effective in cases with a family history of this tumor. Subjects and methods: Forty-two patients were studied; 10 were submitted to lobectomy and 32 to total thyroidectomy, including 23 without lymph node dissection and 9 with lymph node dissection. None of the patients received radioiodine or was maintained under TSH suppression. Results No case of recurrence was detected by imaging methods and there was no increase in thyroglobulin or antithyroglobulin antibodies during follow-up (24 to 72 months). Conclusion The treatment usually recommended for patients with PTC does not need to be modified in the presence of a family history of this tumor if no factors indicating a poor prognosis are present (tumor ≤2 cm, non-aggressive histology, no extensive extrathyroid invasion or important lymph node involvement, complete tumor resection, no evidence of persistent disease after surgery).

Abstract 3117: Pleiotrophin is a marker of poor prognosis in Middle Eastern papillary thyroid carcinoma

2016 ◽  
Author(s):  
Shaham Beg ◽  
Maqbool Ahmed ◽  
Azhar Hussein ◽  
Rong Bu ◽  
Zeeshan Qadri ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Poor Prognosis ◽  
Middle Eastern ◽  
Papillary Thyroid

CHI3L1 overexpression is associated with metastasis and is an indicator of poor prognosis in papillary thyroid carcinoma

2017 ◽  
Vol 18 (3) ◽  
pp. 273-284 ◽  
Author(s):  
Dingyuan Luo ◽  
Haibo Chen ◽  
Penghui Lu ◽  
Xiaojuan Li ◽  
Miaoyun Long ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Poor Prognosis ◽  
Papillary Thyroid

scholarly journals Ultrasound-Guided Radiofrequency Ablation Versus Surgical Resection for the Treatment of T1bN0M0 Papillary Thyroid Carcinoma in Different Age Groups

2021 ◽  
Vol 12 ◽  
Author(s):  
Hongying He ◽  
Rilige Wu ◽  
Jiahang Zhao ◽  
Qing Song ◽  
Yan Zhang ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Tumor Progression ◽  
Surgical Resection ◽  
Age Groups ◽  
Papillary Thyroid ◽  
Voice Change ◽  
Aged Patients ◽  
Treatment Groups

PurposeWe aimed to compare the efficacy and safety of radiofrequency ablation (RFA) to that of surgical resection (SR) in patients with T1bN0M0 papillary thyroid carcinoma (PTC) in different age groups.MethodsTotally, 204 patients with an isolated, solitary, intrathyroidal T1bN0M0 PTC, who underwent either RFA (n=94) or SR (n=110) between April 2014 and December 2019, were retrospectively enrolled and were divided into two subgroups according to age (<45 years, ≧45 years). Patients with pathologically aggressive or advanced lesions were excluded from the study. Tumor progression and procedural complications were the primary and secondary endpoints, respectively. Tumor recurrence in situ, newly discovered tumors, lymph node involvement, or distant metastases indicated tumor progression. Complications included pain, fever, voice change, choking, numbness in the limbs, and cardiac events. Incidence rates of all endpoint events were compared between different age subgroups.ResultsThere were no significant differences in age, sex, and tumor size between the treatment groups. While the RFA group incurred less cost and experienced significantly shorter operative duration than the SR group, no significant differences were observed in incidences of both tumor progression and complications. Further, subgroup analysis of patients <45 years versus those ≧45 years showed no significant differences in the incidence of tumor progression and complications within or between different treatment groups. Older patients in the SR group incurred higher hospital costs than younger counterparts, but this difference was not observed in the RFA group.ConclusionsOur results indicated that RFA had a similar prognosis as that of SR but was associated with lower overall cost in both young (<45 years) and middle-aged patients (≧45 years) with T1bN0M0 PTC. Therefore, RFA may be an effective and safe alternative to surgery for the treatment of patients with T1bN0M0 PTC.

scholarly journals Upregulation of RSPO2-GPR48/LGR4 signaling in papillary thyroid carcinoma contributes to tumor progression

Oncotarget ◽  
2017 ◽  
Vol 8 (70) ◽  
pp. 114980-114994 ◽  
Author(s):  
Yea Eun Kang ◽  
Jin-Man Kim ◽  
Koon Soon Kim ◽  
Joon Young Chang ◽  
Mingyu Jung ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Tumor Progression ◽  
Papillary Thyroid

scholarly journals Activation of the ROCK1/MMP-9 pathway is associated with the invasion and poor prognosis in papillary thyroid carcinoma

2017 ◽  
Vol 51 (4) ◽  
pp. 1209-1218 ◽  
Author(s):  
Dingyuan Luo ◽  
Haibo Chen ◽  
Xiaojuan Li ◽  
Penghui Lu ◽  
Miaoyun Long ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Poor Prognosis ◽  
Papillary Thyroid
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