scholarly journals Phase Difference-Enhanced Magnetic Resonance (MR) Imaging (PADRE) Technique for the Detection of Age-Related Microstructural Changes in Optic Radiation: Comparison with Diffusion Tensor Imaging (DTI)

2017 ◽  
Vol 23 ◽  
pp. 5495-5503 ◽  
Author(s):  
Yasuko Tatewaki ◽  
Tatsushi Mutoh ◽  
Benjamin Thyreau ◽  
Kazuko Omodaka ◽  
Takaki Murata ◽  
...  
2014 ◽  
Vol 45 (6) ◽  
pp. 896-901 ◽  
Author(s):  
Laura Merlini ◽  
Mehrak Anooshiravani ◽  
Aikaterini Kanavaki ◽  
Sylviane Hanquinet

Author(s):  
Piotr Podwalski ◽  
Krzysztof Szczygieł ◽  
Ernest Tyburski ◽  
Leszek Sagan ◽  
Błażej Misiak ◽  
...  

Abstract Diffusion tensor imaging (DTI) is an imaging technique that uses magnetic resonance. It measures the diffusion of water molecules in tissues, which can occur either without restriction (i.e., in an isotropic manner) or limited by some obstacles, such as cell membranes (i.e., in an anisotropic manner). Diffusion is most often measured in terms of, inter alia, fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD), and axial diffusivity (AD). DTI allows us to reconstruct, visualize, and evaluate certain qualities of white matter. To date, many studies have sought to associate various changes in the distribution of diffusion within the brain with mental diseases and disorders. A better understanding of white matter integrity disorders can help us recognize the causes of diseases, as well as help create objective methods of psychiatric diagnosis, identify biomarkers of mental illness, and improve pharmacotherapy. The aim of this work is to present the characteristics of DTI as well as current research on its use in schizophrenia, affective disorders, and other mental disorders.


2020 ◽  
Vol 26 ◽  
Author(s):  
Agnieszka Surowiecka ◽  
Michał Frączek ◽  
Bartosz Mruk ◽  
Marta Matejak-Górska ◽  
Jerzy Walecki ◽  
...  

2008 ◽  
Author(s):  
Don Bigler ◽  
Mark Meadowcroft ◽  
Xiaoyan Sun ◽  
Jeffrey Vesek ◽  
Alex Dresner ◽  
...  

This document describes a suite of new multi-threaded classes for calculating magnetic resonance (MR) T2 and T1 parameter maps implemented using the Insight Toolkit ITK (www.itk.org). Similar to MR diffusion tensor imaging (DTI), MR T2 and T1 parameter maps provide a non-invasive means for quantitatively measuring disease or pathology in-vivo. Included in the suite are classes for reading proprietary Bruker 2dseq and Philips PAR/REC images and example programs and data for validating the new classes.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Xiaoyun Xu ◽  
Matthew Cowan ◽  
Flavio Beraldo ◽  
Amy Schranz ◽  
Patrick McCunn ◽  
...  

AbstractWe have previously reported long-term changes in the brains of non-concussed varsity rugby players using magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) and functional magnetic imaging (fMRI). Others have reported cognitive deficits in contact sport athletes that have not met the diagnostic criteria for concussion. These results suggest that repetitive mild traumatic brain injuries (rmTBIs) that are not severe enough to meet the diagnostic threshold for concussion, produce long-term consequences. We sought to characterize the neuroimaging, cognitive, pathological and metabolomic changes in a mouse model of rmTBI. Using a closed-skull model of mTBI that when scaled to human leads to rotational and linear accelerations far below what has been reported for sports concussion athletes, we found that 5 daily mTBIs triggered two temporally distinct types of pathological changes. First, during the first days and weeks after injury, the rmTBI produced diffuse axonal injury, a transient inflammatory response and changes in diffusion tensor imaging (DTI) that resolved with time. Second, the rmTBI led to pathological changes that were evident months after the injury including: changes in magnetic resonance spectroscopy (MRS), altered levels of synaptic proteins, behavioural deficits in attention and spatial memory, accumulations of pathologically phosphorylated tau, altered blood metabolomic profiles and white matter ultrastructural abnormalities. These results indicate that exceedingly mild rmTBI, in mice, triggers processes with pathological consequences observable months after the initial injury.


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