scholarly journals Comparison of T Helper Cell Patterns in Primary Open-Angle Glaucoma and Normal-Pressure Glaucoma

2018 ◽  
Vol 24 ◽  
pp. 1988-1996 ◽  
Author(s):  
Chunyu Guo ◽  
Ningbo Wu ◽  
Xiaoyin Niu ◽  
Yue Wu ◽  
Dongfeng Chen ◽  
...  
2014 ◽  
Vol 133 (10) ◽  
pp. 1319-1330 ◽  
Author(s):  
Jessica N. Cooke Bailey ◽  
Brian L. Yaspan ◽  
Louis R. Pasquale ◽  
Michael A. Hauser ◽  
Jae H. Kang ◽  
...  

2021 ◽  
Vol 6 (6-1) ◽  
pp. 82-95
Author(s):  
E. V. Kozina ◽  
I. A. Kokh ◽  
A. V. Toropov ◽  
E. M. Kadomtseva ◽  
E. Yu. Mozheyko

The review assesses physical exercises as an additional non-pharmacological mean of combating the progression of primary open-angle glaucoma. The ophthalmic hypotensive effect is determined by the type of exercise, its duration and intensity. Moderate aerobic activity is preferred. Among dynamic exercises, jogging has the greatest hypotensive effect. Upper body isometric resistance training provides a more lasting decrease in ophthalmotonus. The decrease in intraocular pressure (IOP) in patients with glaucoma is several times more pronounced in comparison with healthy people and occurs regardless of the nature of the local drug antihypertensive therapy. After the termination of classes IOP returns to the previous level on average within a month. An increase in ocular perfusion pressure associated with physical activity dictates the appropriateness of physical exercise for patients with pseudo-normal pressure glaucoma. The combination of hypotensive, vascular, neuroprotective effects of physical activity with a high level of physical fi tness does not exclude a decrease in the risk of development and progression of primary open-angle glaucoma. The development of indications for the use of physical activity by patients with advanced glaucoma, including those who have undergone hypotensive surgery, remains relevant. The type, intensity, dosage and mode of performing the recommended physical exercises require an individual choice.


Author(s):  
Deepa Rastogi ◽  
Andrea Andrade ◽  
Stephen M. Canfield ◽  
Charles B. Hall ◽  
Carmen R. Isasi ◽  
...  

2002 ◽  
Vol 102 (6) ◽  
pp. 623-630 ◽  
Author(s):  
Clive M. BROWN ◽  
Matthias DÜTSCH ◽  
Georg MICHELSON ◽  
Bernhard NEUNDÖRFER ◽  
Max J. HILZ

Autonomic neuropathy may contribute to the pathophysiology of both open-angle and normal-pressure glaucoma. However, autonomic function has not been studied extensively in these diseases. We evaluated baroreflex control of the heart and blood vessels in open-angle and normal-pressure glaucoma. We studied 14 patients with open-angle glaucoma, 15 with normal-pressure glaucoma and 17 controls. Sinusoidal neck suction (0 to -30mmHg) was applied at 0.1Hz to assess the sympathetic modulation of the heart and blood vessels, and at 0.2Hz to assess the effect of parasympathetic stimulation on the heart. Baseline recordings showed no significant differences between the groups. The RR-interval response of the controls to neck suction at 0.1Hz (3.88±0.32 to 6.65±0.44lnms2) was significantly greater than that of the open-angle glaucoma patients (4.22±0.28 to 5.56±0.26lnms2) and the normal-pressure glaucoma patients (4.53±0.27 to 5.53±0.37lnms2) (P<0.05). The low-frequency power of diastolic blood pressure increased significantly in the controls (0.48±0.08 to 2.76±0.72mmHg2; P<0.01) during 0.1Hz neck suction, but did not change significantly in patients with either open-angle glaucoma or normal-pressure glaucoma. The RR-interval response in the control group (3.45±0.52lnms2) to neck suction at 0.2Hz was significantly greater than that of the normal-pressure glaucoma patients (1.84±0.32lnms2) and the open-angle glaucoma patients (1.58±0.35lnms2) (P<0.05). The decreased sympathetic and parasympathetic modulation during baroreceptor stimulation in patients with open-angle glaucoma and normal-pressure glaucoma suggests that autonomic dysfunction may contribute to the pathogenesis of both diseases.


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